IL2RG 抗体
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北京 101111
Quick Overview for IL2RG 抗体 (ABIN2664201)
抗原
See all IL2RG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 犬
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
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别名
- CD132
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背景
- CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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