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CD45RB 抗体 (PE-Cy7)

CD45RB 适用: 小鼠 FACS, IHC 宿主: 大鼠 Monoclonal C363-16A PE-Cy7
产品编号 ABIN2659281
发货至: 中国
  • 抗原 See all CD45RB 抗体
    CD45RB
    适用
    • 57
    • 18
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    小鼠
    宿主
    • 47
    • 18
    • 12
    大鼠
    克隆类型
    • 76
    • 1
    单克隆
    标记
    • 23
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    This CD45RB antibody is conjugated to PE-Cy7
    应用范围
    • 74
    • 41
    • 35
    • 26
    • 21
    • 17
    • 7
    • 4
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    克隆位点
    C363-16A
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD45RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD45RB
    别名
    CD45RB (CD45RB 产品)
    背景
    CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naive T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naive to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
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