SH3BP2 抗体
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北京 101111
Quick Overview for SH3BP2 抗体 (ABIN264981)
抗原
See all SH3BP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to 3BP2.
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纯化方法
- Purified
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免疫原
- Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
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亚型
- IgG
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应用备注
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Western Blot: Detects a 85 kDa band in murine fibroblasts transfected with 3BP2.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline and 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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别名
- SH3BP2
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背景
- 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.Synonyms: 3BP-2, 3BP2, SH3 domain-binding protein 2, SH3BP-2
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基因ID
- 6452
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NCBI登录号
- NP_001116153
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UniProt
- P78314
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途径
- TCR Signaling
抗原
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