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SH3BP2 抗体

This anti-SH3BP2 antibody is a 绵羊 多克隆 antibody detecting SH3BP2 in WB. Suitable for 小鼠.
产品编号 ABIN264981
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SH3BP2 抗体 (ABIN264981)

抗原

See all SH3BP2 抗体
SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

适用

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小鼠

宿主

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绵羊

克隆类型

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多克隆

标记

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This SH3BP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody reacts to 3BP2.

    纯化方法

    Purified

    免疫原

    Antibody developed using SH2 domain of the 3BP2 protein fused to GST.

    亚型

    IgG
  • 应用备注

    Western Blot: Detects a 85 kDa band in murine fibroblasts transfected with 3BP2.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline and 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原

    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

    别名

    SH3BP2

    背景

    3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.Synonyms: 3BP-2, 3BP2, SH3 domain-binding protein 2, SH3BP-2

    基因ID

    6452

    NCBI登录号

    NP_001116153

    UniProt

    P78314

    途径

    TCR Signaling
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