CD45.2 抗体 (PE-Cy7)
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- 抗原 See all CD45.2 products
- CD45.2 (CD45 (CD45.2 Allogen))
- 适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD45.2 antibody is conjugated to PE-Cy7
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The 104 monoclonal antibody specifically reacts with the mouse CD45 Molecule, the Leukocyte Common Antigen (LCA) which occurs in the alloantigen CD45.2-expressing mouse strains (C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He).
- 纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- 克隆位点
- 104
- 亚型
- IgG2a kappa
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- 储存条件
- 4 °C
- 储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- 抗原
- CD45.2 (CD45 (CD45.2 Allogen))
- 别名
- CD45.2 (CD45.2 产品)
- 背景
- The 104 monoclonal antibody specifically reacts with the MouseCD45 Molecule, the Leukocyte Common Antigen (LCA) which occurs in the alloantigen CD45.2-expressing Mousestrains (C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He). The 104 monoclonal antibody does not react with the leukocytes of the CD45.1-expressing Mousestrains (DA, SJL/J, RIII, and STS/A). The CD45 Molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the Mousestrains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The 104 antibody inhibits some of the B lymphocytes responses, reduces the serum IgG levels, and influences the autoimmune renal pathology.
- 基因ID
- 19264
- UniProt
- P06800
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