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ITGB1 抗体 (PE)

This anti-ITGB1 antibody is a 仓鼠 单克隆 antibody detecting ITGB1 in FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN181970
发货至: 中国

Quick Overview for ITGB1 抗体 (PE) (ABIN181970)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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小鼠, 大鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This ITGB1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

HM beta 1-1
  • 特异性

    This antibody recognizes the Integrin beta 1 subunit (CD29). Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. (Ref.1) We recommend the use of SM2210LE for this purpose.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Purified mouse VLA-4 antigen. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Neat-1/5): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.25 mL distilled water.

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29 / Integrin beta-1

    背景

    CD29 is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

    基因ID

    16412

    NCBI登录号

    NP_034708

    UniProt

    P09055

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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