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UNC13A/Munc13-1 抗体 (AA 3-317)

This anti-UNC13A/Munc13-1 antibody is a 小鼠 单克隆 antibody detecting UNC13A/Munc13-1 in WB, ELISA 和 IP. Suitable for 小鼠, 大鼠 和 斑马鱼. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN1742276
发货至: 中国

Quick Overview for UNC13A/Munc13-1 抗体 (AA 3-317) (ABIN1742276)

抗原

See all UNC13A/Munc13-1 (UNC13A) 抗体
UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

适用

  • 6
  • 4
  • 3
  • 2
  • 1
小鼠, 大鼠, 斑马鱼

宿主

  • 5
  • 2
  • 1
小鼠

克隆类型

  • 8
单克隆

标记

  • 8
This UNC13A/Munc13-1 antibody is un-conjugated

应用范围

  • 7
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunoprecipitation (IP)

克隆位点

266B1
  • 抗原表位

    • 2
    • 1
    • 1
    AA 3-317

    特异性

    Specific for munc 13-1.

    免疫原

    Recombinant rat munc 13-1 (aa 3-317).

    亚型

    IgG2b
  • 应用备注

    WB: 1:500 up to 1:5000,

    说明

    IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected. ICC: limited to methanol fixation. ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100µl H2O to get a 1mg/ml solution in PBS.

    缓冲液

    PBS. Albumin and azide were added for stabilization.

    储存液

    Sodium azide

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C

    储存方法

    Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Kaeser-Woo, Younts, Yang, Zhou, Wu, Castillo, Südhof: "Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 23, pp. 9769-80, (2013) (PubMed).

    Dudenhöffer-Pfeifer, Schirra, Pattu, Halimani, Maier-Peuschel, Marshall, Matti, Becherer, Dirks, Jung, Lipp, Hoth, Sester, Krause, Rettig: "Different Munc13 isoforms function as priming factors in lytic granule release from murine cytotoxic T lymphocytes." in: Traffic (Copenhagen, Denmark), Vol. 14, Issue 7, pp. 798-809, (2013) (PubMed).

    Maas, Torres, Altrock, Leal-Ortiz, Wagh, Terry-Lorenzo, Fejtova, Gundelfinger, Ziv, Garner: "Formation of Golgi-derived active zone precursor vesicles." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 32, pp. 11095-108, (2012) (PubMed).

    Martín, Bartolomé-Martín, Torres, Sánchez-Prieto: "Non-additive potentiation of glutamate release by phorbol esters and metabotropic mGlu7 receptor in cerebrocortical nerve terminals." in: Journal of neurochemistry, Vol. 116, Issue 4, pp. 476-85, (2011) (PubMed).

    Martín, Durroux, Ciruela, Torres, Pin, Sánchez-Prieto: "The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17907-17, (2010) (PubMed).

    Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

  • 抗原

    UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

    别名

    Munc 13-1

    途径

    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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