ATG2B 抗体 (N-Term)
Quick Overview for ATG2B 抗体 (N-Term) (ABIN1449993)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B
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亚型
- IgG
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anti-Autophagy Related 2B (ATG2B) (AA 1357-1536) antibody
ATG2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (N-Term) antibodyATG2B 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (AA 1360-1600) antibodyATG2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (AA 118-146), (N-Term) antibodyATG2B 适用: 人 WB 宿主: 兔 Polyclonal RB33277 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ATG2B (Autophagy Related 2B (ATG2B))
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别名
- ATG2B
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.Synonyms: Autophagy related 2 homolog B
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分子量
- 229 kDa
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基因ID
- 55102
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NCBI登录号
- NP_060506
抗原
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