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- 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ICAM-3/CD50 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with human CD50 antigen.
- 纯化方法
- Protein A agarose
- 免疫原
- Human myeloma cell line (RPMI8226)
- 克隆位点
- YUK2
- 亚型
- IgG1
- Top Product
- Discover our top product ICAM3 Primary Antibody
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anti-Intercellular Adhesion Molecule 3 (ICAM3) antibody
ICAM3 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-171 unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) antibodyICAM3 适用: 人 FACS, IHC (p), Func 宿主: 小鼠 Monoclonal MEM-04 unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 30-203) antibodyICAM3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2D11D1 unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 200-547) antibodyICAM3 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 30-547) antibodyICAM3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) antibody (Biotin)ICAM3 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-171 Biotin
anti-Intercellular Adhesion Molecule 3 (ICAM3) antibody (PE)ICAM3 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-171 PE
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 46-197) antibodyICAM3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 30-130) antibodyICAM3 适用: 人 ELISA, IHC (p), ICC, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 259-491) antibodyICAM3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 1 % BSA and 0.09 % NaN3
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8 °C.
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- 抗原
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
- 别名
- CD50 / ICAM3 (ICAM3 产品)
- 背景
- Intercellular adhesion molecules (ICAMs) are type I transmem brane glycoproteins, which contain 2-9 immunoglobulin-like C2-type domains, and bind to lymphocyte function- associated antigen-1 (LFA-1, also known as a L/ ß 2 or CD11a/CD18). ICAM-3 (CD50) is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. ICAM-3 is the most important ligand for LFA-1 in the initiation of the immune response because the expression of ICAM-1 (CD54) and ICAM-2 (CD102) on resting leukocytes is very low or not at all. Previous studies suggest that ICAM-3 acts as a biologically significant molecule playing a role in HIV-1 transcription and replication, particularly in resting CD4 + T cells. It has been suggested that dendritic cell-specific ICAM grabbing nonintegrin (DC-SIGN, CD209), a C-type lectin of macrophages and DCs, is an additional ligand of ICAM-3. The interaction of DC-SIGN with ICAM-3 establishes initial contact between dendritic cells and resting T-cells during antigen presentation.Synonyms: CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3
- 基因ID
- 3385
- NCBI登录号
- NP_002153
- UniProt
- P32942
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