CD1a 抗体
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北京 101111
Quick Overview for CD1a 抗体 (ABIN120678)
抗原
See all CD1a 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacts with CD1a (T6), a 49 KDa polypeptide associated with b2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.
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纯化方法
- Protein G-affinity chromatography
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human thymocytes
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亚型
- IgG1
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anti-CD1a (CD1a) antibody
CD1a 适用: 人 IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-CD1a (CD1a) (AA 151-250) antibodyCD1a 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rC1A-711 unconjugated Recombinant Antibody
anti-CD1a (CD1a) antibody (FITC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 FITC
anti-CD1a (CD1a) antibody (PE)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 PE
anti-CD1a (CD1a) antibody (APC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 APC
anti-CD1a (CD1a) (full length) antibodyCD1a 适用: 人 IHC 宿主: 小鼠 Monoclonal 001M unconjugated Recombinant Antibody
anti-CD1a (CD1a) (AA 1-311) antibodyCD1a 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal M1-2-1B5 unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人, 猕猴 FACS, IHC, IF, WB, StM 宿主: 小鼠 Monoclonal O10 unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 兔 Monoclonal C1A-1506R unconjugated Recombinant Antibody
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应用备注
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Flow cytometry. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- CD1a
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别名
- CD1a
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背景
- CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen
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UniProt
- P06126
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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