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ITGA2 抗体

ITGA2 适用: 人 FACS, IP, EIA 宿主: 小鼠 Monoclonal 31H4 unconjugated
产品编号 ABIN119427
发货至: 中国
  • 抗原 See all ITGA2 抗体
    ITGA2 (Integrin alpha 2 (ITGA2))
    适用
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    宿主
    • 68
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    小鼠
    克隆类型
    • 86
    • 61
    单克隆
    标记
    • 64
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    This ITGA2 antibody is un-conjugated
    应用范围
    • 70
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    31H4 has been identified as being capable of immunoprecipitating the integrin a2 subunit from cell lines surface labelled with 125I. It has been confirmed specific to a2 by relative expression of antigen on various cell lines by flow cytometry, and recognition of affinity purified a2b1 in dot blots.
    无交叉反应
    大鼠
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Purified human beta1 integrin preparation from HT1080 fibrosarcoma cell extract. Spleen cells from immunised BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line.
    克隆位点
    31H4
    亚型
    IgG1
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • 应用备注
    Flow cytometry: 1/25 - 1/50, Immunoprecipitation: 25 - 50 μg/mL. ELISA: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ITGA2 (Integrin alpha 2 (ITGA2))
    别名
    CD49b / ITGA2 (ITGA2 产品)
    背景
    Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
    基因ID
    3673
    NCBI登录号
    NP_002194
    UniProt
    P17301
    途径
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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