ITGA2 抗体
-
- 抗原 See all ITGA2 抗体
- ITGA2 (Integrin alpha 2 (ITGA2))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This ITGA2 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- 特异性
- 31H4 has been identified as being capable of immunoprecipitating the integrin a2 subunit from cell lines surface labelled with 125I. It has been confirmed specific to a2 by relative expression of antigen on various cell lines by flow cytometry, and recognition of affinity purified a2b1 in dot blots.
- 无交叉反应
- 大鼠
- 纯化方法
- Affinity chromatography on Protein G
- 免疫原
- Purified human beta1 integrin preparation from HT1080 fibrosarcoma cell extract. Spleen cells from immunised BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line.
- 克隆位点
- 31H4
- 亚型
- IgG1
- Top Product
- Discover our top product ITGA2 Primary Antibody
-
-
- 应用备注
-
Flow cytometry: 1/25 - 1/50, Immunoprecipitation: 25 - 50 μg/mL. ELISA: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- ITGA2 (Integrin alpha 2 (ITGA2))
- 别名
- CD49b / ITGA2 (ITGA2 产品)
- 背景
- Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
- 基因ID
- 3673
- NCBI登录号
- NP_002194
- UniProt
- P17301
- 途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
-