CD97 抗体
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北京 101111
Quick Overview for CD97 抗体 (ABIN119250)
抗原
See all CD97 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure (by SDS-PAGE)
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免疫原
- PHA-activated blood cells
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亚型
- IgG1
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应用备注
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Flow cytometry: 1/200 - 1/400, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD97
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别名
- CD97
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背景
- CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.Synonyms: Leukocyte antigen CD97
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基因ID
- 976
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NCBI登录号
- NP_001020331
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UniProt
- P48960
抗原
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