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CD53 抗体 (FITC)

This anti-CD53 antibody is a 小鼠 单克隆 antibody detecting CD53 in FACS. Suitable for 人.
产品编号 ABIN118728
发货至: 中国

Quick Overview for CD53 抗体 (FITC) (ABIN118728)

抗原

See all CD53 抗体
CD53

适用

  • 66
  • 4
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宿主

  • 40
  • 28
小鼠

克隆类型

  • 42
  • 23
  • 3
单克隆

标记

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  • 2
  • 1
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This CD53 antibody is conjugated to FITC

应用范围

  • 44
  • 32
  • 25
  • 18
  • 13
  • 13
  • 12
  • 12
  • 9
  • 8
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Flow Cytometry (FACS)

克隆位点

MEM-53
  • 纯化方法

    Ion exchange chromatography

    亚型

    IgG1
  • 应用备注

    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. Shelf life one year from despatch.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD53

    别名

    CD53

    背景

    CD53 is a member of the tetraspan family of molecules, and is expressed by all leucocytes, but is absent from red cells and platelets. Most of the tetraspan family of molecules are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2 generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 is a glycoprotein of 32-40 kDa belonging to the tetraspans family (TM4SF). CD53 antigen is exclusivelly expressed on leucocytes (not present on platelets, red blood cells and non-hematopoietic cells). CD53 is important for signal transduction. CD53 cross-linking promotes activation of human B cells and rat macrophages.Synonyms: Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25

    基因ID

    963

    NCBI登录号

    NP_000551

    UniProt

    P19397
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