CD3 抗体
Quick Overview for CD3 抗体 (ABIN1177371)
抗原
See all CD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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亚型
- IgG3 lambda
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." in: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).
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: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." in: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).
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- CD3
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别名
- CD3
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背景
- Clone SP34 reacts with human form of the 20 kDa epsilon subunit of the CD3 antigen/T-cell receptor (TCR) complex. This clone also cross-reacts with a major subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of rhesus or cynomolgus and pigtail macaque monkeys. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, with the majority of CD3-positive cells being negative when dual stained with antibodies to B or NK cell markers.
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途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
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