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CD3 抗体

This anti-CD3 antibody is a 小鼠 单克隆 antibody detecting CD3 in FACS. Suitable for 猕猴, Cynomolgus 和 Baboon. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1177371
发货至: 中国

Quick Overview for CD3 抗体 (ABIN1177371)

抗原

See all CD3 抗体
CD3

适用

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猕猴, Cynomolgus, Baboon

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

SP34
  • 品牌

    BD Pharmingen™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    亚型

    IgG3 lambda
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Sancho, Ledbetter, Choi, Kanner, Deans, Terhorst: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." in: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).

  • 抗原

    CD3

    别名

    CD3

    背景

    Clone SP34 reacts with human form of the 20 kDa epsilon subunit of the CD3 antigen/T-cell receptor (TCR) complex. This clone also cross-reacts with a major subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of rhesus or cynomolgus and pigtail macaque monkeys. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, with the majority of CD3-positive cells being negative when dual stained with antibodies to B or NK cell markers.

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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