PDGFRB 抗体
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Quick Overview for PDGFRB 抗体 (ABIN111188)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for the extracellular domain of the PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. This antibody does not recognize PDGF receptor alpha. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Human skin fibroblast cell membrane extracts.
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亚型
- IgG1
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应用备注
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Flow Cytometry: 25 μg/mL. Immunoprecipitation. Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: 25 μg/mL. Recommended Positive Control: Human breast cancer tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- CD140b / PDGFRB
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背景
- PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3.Synonyms: Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, PDGF Receptor beta, PDGF-R-beta
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基因ID
- 5159
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NCBI登录号
- NP_002600
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UniProt
- P09619
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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