beta-2 Microglobulin 抗体
Quick Overview for beta-2 Microglobulin 抗体 (ABIN111076)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human beta 2-Microglobulin (MW 12 kDa). Recognizes the HLA-beta 2-Microglobulin complex, free or associated with the membrane. Does not react with other species. The exact epitope for the antibody has not been mapped.
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纯化方法
- Protein A Chromatography
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免疫原
- Purified human Beta 2-Microglobulin
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亚型
- IgG2a
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应用备注
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Purification of the HLA antigens associated with beta 2-Microglobulin. Fluorescence Microscopy or Flow Cytometry: 2 μg/5x10e5 cells/test. Immunohistochemistry (Frozen Sections or Cell Smears): 1/25-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1.0 mL distilled water
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浓度
- 0.2 mg/mL (prior to lyophilization)
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缓冲液
- PBS, None, 1 mg/mL BSA
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Following reconstitution store the antibody at -20 °C.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- beta-2-Microglobulin
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背景
- Beta-2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin
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基因ID
- 567
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NCBI登录号
- NP_004039
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UniProt
- P61769
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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