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beta-2 Microglobulin 抗体

This 小鼠 单克隆 anti-beta-2 Microglobulin antibody (Clone B1G6) specifically detects beta-2 Microglobulin in FACS, IF 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN111076
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for beta-2 Microglobulin 抗体 (ABIN111076)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

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小鼠

克隆类型

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单克隆

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

B1G6
  • 特异性

    Human beta 2-Microglobulin (MW 12 kDa). Recognizes the HLA-beta 2-Microglobulin complex, free or associated with the membrane. Does not react with other species. The exact epitope for the antibody has not been mapped.

    纯化方法

    Protein A Chromatography

    免疫原

    Purified human Beta 2-Microglobulin

    亚型

    IgG2a
  • 应用备注

    Purification of the HLA antigens associated with beta 2-Microglobulin. Fluorescence Microscopy or Flow Cytometry: 2 μg/5x10e5 cells/test. Immunohistochemistry (Frozen Sections or Cell Smears): 1/25-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.0 mL distilled water

    浓度

    0.2 mg/mL (prior to lyophilization)

    缓冲液

    PBS, None, 1 mg/mL BSA

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Following reconstitution store the antibody at -20 °C.
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    beta-2-Microglobulin

    背景

    Beta-2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

    基因ID

    567

    NCBI登录号

    NP_004039

    UniProt

    P61769

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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