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抗Rat (Rattus) 抗体:
抗Mouse (Murine) 抗体:
Human Monoclonal RUVBL1 Primary Antibody for IF, PLA - ABIN563710
Kaji, Fertig, Medsger, Satoh, Hoshino, Hamaguchi, Hasegawa, Lucas, Schnure, Ogawa, Sato, Takehara, Fujimoto, Kuwana: Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement. in Arthritis care & research 2014
Human Polyclonal RUVBL1 Primary Antibody for ICC, IF - ABIN4351482
Tyleckova, Hrabakova, Mairychova, Halada, Radova, Dzubak, Hajduch, Gadher, Kovarova: Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs. in International journal of molecular sciences 2013
xPontin and xReptin (显示 RUVBL2 抗体) are essential genes regulating cell proliferation in early Xenopus embryogenesis through interaction with c-Myc (显示 MYC 抗体)
Pontin has a mitosis-specific function in regulating microtubule assembly
Zebrafish pontin mutants display phenotypes tightly associated with cilia defects, and cilia motility is (显示 DNAI1 抗体)lost in a n (显示 DNAI2 抗体)umber of ciliated tissues along with a reduction in the number of outer and inner dynein arms.
the reptin (显示 RUVBL2 抗体)/pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin (显示 CTNNB1 抗体) pathway
The interaction between RUVBL1 and ITFG1 (显示 ITFG1 抗体) is required for breast cancer cell collective invasion and progression.
Methylation of RUVBL1 by the arginine methyltransferase PRMT5 (显示 PRMT5 抗体) is required for homologous recombination-mediated double-strand break repair by promoting TIP60 (显示 KAT5 抗体)-mediated histone H4K16 acetylation.
association of c-FLIPL (显示 CFLAR 抗体) and TIP49 provided an additional mechanism involved in c-FLIPL (显示 CFLAR 抗体)-mediated functions, including Wnt (显示 WNT2 抗体) activation
Adenovirus E1A (显示 BCKDHA 抗体) was found to bind to RuvBL1 via the C terminus of E1A (显示 BCKDHA 抗体), and this interaction was important for suppression of interferon (显示 IFNA 抗体)-stimulated gene transcriptional activation and recruitment of E1A (显示 BCKDHA 抗体) to interferon (显示 IFNA 抗体)-regulated promoters.
The interaction of ECD with RUVBL1, and its CK2-mediated phosphorylation, independent of its interaction with PIH1D1, are important for its cell cycle regulatory function.
Results highlight an important role and mechanism for Pontin, a new mutp53 partner, in promoting mutp53 GOF in tumorigenesis.
data thus demonstrate that RUVBL1 is essential for efficient mitosis and proliferation.
by means of molecular docking approaches we first modeled the structures of hetero-hexameric TIP49 ( TIP49a and TIP49b (显示 RUVBL2 抗体) )complexes with short ds-DNA fragments (20 base pairs with different GC content) within the central channel of hexameric ring
Study showed that pontin is up-regulated in renal cell carcinoma (显示 MOK 抗体) (RCC (显示 XRCC1 抗体)) and high cytoplasmic pontin expression was associated with poor survival of RCC (显示 XRCC1 抗体) patients.
RuvbL1 and RuvbL2 (显示 RUVBL2 抗体) enhance aggresome formation and disaggregate amyloid fibrils.
In mouse testis, Pontin is essential for the stabilization of axonemal dynein intermediate chain 1 (DNAI1 (显示 DNAI1 抗体)) and DNAI2 (显示 DNAI2 抗体), the first appreciated step in axonemal dynein arm assembly.
accumulating E2f1 (显示 E2F1 抗体) progressively recruits a Pontin/Reptin (显示 RUVBL2 抗体) complex to open the chromatin conformation at E2f (显示 E2F1 抗体) target genes and amplifies the E2f (显示 E2F1 抗体) transcriptional response.
Pontin functions as an essential coactivator for Oct4 (显示 POU5F1 抗体)-dependent large intergenic noncoding RNA expression in mouse embryonic stem cells.
Loss of Ruvbl1 gene is associated with bone marrow failure.
nuclear DNA helicase that binds TBP; involved in recombination and transcription
, RuvB-like 1 (E. coli)
, RuvB-like 1-like
, ruvB-like 1-like
, RuvB-like 1
, 49 kDa TATA box-binding protein-interacting protein
, 49 kDa TBP-interacting protein
, 54 kDa erythrocyte cytosolic protein
, INO80 complex subunit H
, NMP 238
, RuvB (E coli homolog)-like 1
, TATA binding protein interacting protein 49 kDa
, TIP60-associated protein 54-alpha
, nuclear matrix protein 238
, pontin 52
, DNA helicase p50
, RuvB-like protein 1
, Pontin 52