anti-TCF3 (TCF3) 抗体产品概述

Full name:
anti-Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) 抗体 (TCF3)
在www.antibodies-online.cn可供145 Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) 抗体的24不同的供货商。 再加上,我们可以发TCF3 蛋白 (7)TCF3 试剂盒 (6)和数多这个蛋白质的别的产品。 总共170 TCF3产品已列进来了。
A1, AA408400, ALF2, AW209082, bhlhb21, e2a, E12, E12/E47, E47, G12, itf1, ME2, Pan1, Pan2, TCF-3, Tcf3, tcf3a, TCF7L1, tcfe2a, vdir, xtcf-3, xtcf3, zgc:113045

最受欢迎的抗anti-TCF3 (TCF3) 抗体


抗Human TCF3 抗体:

抗Mouse (Murine) TCF3 抗体:

抗Rat (Rattus) TCF3 抗体:

所有可销售的anti-TCF3 抗体


引用最多的anti-TCF3 抗体

  1. Human Polyclonal TCF3 Primary Antibody for FACS, IHC (p) - ABIN657912 : Hirose, Inukai, Kikuchi, Furukawa, Ikawa, Kawamoto, Oram, Göttgens, Kiyokawa, Miyagawa, Okita, Akahane, Zhang, Kuroda, Honna, Kagami, Goi, Kurosawa, Look, Matsui, Inaba, Sugita: Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19). in Blood 2010 (PubMed)
    Show all 5 references for 657912

  2. Human Monoclonal TCF3 Primary Antibody for ELISA, FACS - ABIN2869482 : Firulli, Hadzic, McDaid, Firulli: The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for 2869482

  3. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1533168 : Kamps, Murre, Sun, Baltimore: A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. in Cell 1990 (PubMed)
    Show all 3 references for 1533168

  4. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1533624 : Nourse, Mellentin, Galili, Wilkinson, Stanbridge, Smith, Cleary: Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. in Cell 1990 (PubMed)
    Show all 3 references for 1533624

  5. Human Polyclonal TCF3 Primary Antibody for IHC, ELISA - ABIN1532141 : Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: The DNA sequence and biology of human chromosome 19. ... in Nature 2004 (PubMed)
    Show all 3 references for 1532141

  6. Cow (Bovine) Polyclonal TCF3 Primary Antibody for WB - ABIN2780485 : Amemiya-Kudo, Oka, Ide, Matsuzaka, Sone, Yoshikawa, Yahagi, Ishibashi, Osuga, Yamada, Murase, Shimano: Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47. in The Journal of biological chemistry 2005 (PubMed)


Human Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. Poly (ADP-ribose) polymerase (显示 PARP1 抗体) inhibitors selectively induce cytotoxicity in TCF3-HLF (显示 EPAS1 抗体)-positive leukemic cells.

  2. MiR (显示 MLXIP 抗体)-138 may be a tumor suppressor and potential prognostic biomarker in cervical cancer. Its downstream target, TCF3, may also regulate cancer development in a reverse manner as miR (显示 MLXIP 抗体)-138.

  3. High levels of TCF3 in gliomas promote glioma development through the Akt (显示 AKT1 抗体) and Erk (显示 EPHB2 抗体) pathways.

  4. TWIST1 (显示 TWIST1 抗体)-E12 (显示 ELSPBP1 抗体) protein heterodimeric complexes may thus constitute the main active forms of TWIST1 (显示 TWIST1 抗体) with regard to senescence inhibition over the time course of breast tumorigenesis.

  5. Review of the role of the E2A-PBX1 (显示 PBX1 抗体) gene rearrangement in the prognosis of childhood acute lymphoblastic leukemia and its central nervous system relapse.

  6. Our data suggest that E2A antagonism of PU.1 activity contributes to its ability to commit multipotential hematopoietic progenitors to the lymphoid lineages.

  7. E47 is a novel substrate of PAK5 (显示 PAK6 抗体), and PAK5 (显示 PAK6 抗体)-mediated phosphorylation of E47 promotes epithelial-mesenchymal transition. High expression of phospho-E47 was associated with an aggressive phenotype of colon cancer and metastasis.

  8. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3-PBX1 (显示 PBX1 抗体) as well as an enrichment of genes involved in immunity and infection pathways in ETV6 (显示 ETV6 抗体)-RUNX1 (显示 RUNX1 抗体) subtype

  9. Over expression of E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.

  10. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3-HLF (显示 EPAS1 抗体) ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids.

Mouse (Murine) Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. If Gfi1 (显示 ZNF163 抗体) levels fall below a threshold, Id1 (显示 ID1 抗体) expression increases and renders E2A unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  2. these data identified E2A and E2-2 (显示 TCF4 抗体) as central regulators of B cell immunity.

  3. down-regulation of Id3 (显示 ID3 抗体) in B cells is essential for releasing E2A and E2-2 (显示 TCF4 抗体), which in a redundant manner are required for antigen-induced B cell differentiation.

  4. Data suggest a novel mechanism of drug resistance in which E2a and PRC2 drive changes in the B-cell epigenome; these alterations attenuate alkylating agent treatment-induced apoptosis.

  5. These findings suggest that miR (显示 MLXIP 抗体)-506-3p played an important role in regulating NSC proliferation and differentiation via targeting TCF3 (显示 TCF7L1 抗体), and provide a promising avenue for future in-depth research into the functions of miR (显示 MLXIP 抗体)-506-3p and TCF3 (显示 TCF7L1 抗体) in nervous system development.

  6. Conditional expression of E2A-HLF (显示 HLF 抗体) induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  7. Upregulation of E12/E47 by HBx ultimately and concomitant repression of E-cadherin (显示 CDH1 抗体) expression led to epithelial-mesenchymal transition in human hepatocytes.

  8. Mechanistically, E47 repressed the expression of several astrocyte-specific genes in adult NSPCs.

  9. Tcf3 (显示 TCF7L1 抗体) is upregulated in skin wounds and Tcf3 (显示 TCF7L1 抗体) overexpression accelerates keratinocyte migration and skin wound healing.

  10. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (显示 LOXL3 抗体) and E47 in tumor growth and their requirement for lung metastasis.

Xenopus laevis Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) interaction partners

  1. Data indicte that Tcf-1 (显示 HNF1A 抗体) and Lef-1 (显示 LEF1 抗体) exhibit a function in the axis induction assay, which is lacking in Tcf-3 and -4.

TCF3 抗原简介

Antigen Summary

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1\;19), with PBX1), childhood leukemia (t(19\;19), with TFPT) and acute leukemia (t(12\;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Alternative names and synonyms associated with TCF3

  • transcription factor 3b (tcf3b) 抗体
  • transcription factor 3 (TCF3) 抗体
  • transcription factor 3 (Tcf3) 抗体
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (tcf3) 抗体
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3) 抗体
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (Tcf7l1) 抗体
  • A1 抗体
  • AA408400 抗体
  • ALF2 抗体
  • AW209082 抗体
  • bhlhb21 抗体
  • e2a 抗体
  • E12 抗体
  • E12/E47 抗体
  • E47 抗体
  • G12 抗体
  • itf1 抗体
  • ME2 抗体
  • Pan1 抗体
  • Pan2 抗体
  • TCF-3 抗体
  • Tcf3 抗体
  • tcf3a 抗体
  • TCF7L1 抗体
  • tcfe2a 抗体
  • vdir 抗体
  • xtcf-3 抗体
  • xtcf3 抗体
  • zgc:113045 抗体

Protein level used designations for TCF3

transcription factor E2-alpha , transcription factor 3 , VDR interacting repressor , class B basic helix-loop-helix protein 21 , helix-loop-helix protein HE47 , immunoglobulin transcription factor 1 , kappa-E2-binding factor , negative vitamin D response element-binding protein , transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) , transcription factor ITF-1 , vitamin D receptor-interacting repressor , TCF-3 , immunoglobulin enhancer-binding factor E12/E47 , transcription factor A1 , transcription factor E2a , pancreas specific transcription factor 1c , transcription regulator Pan , transcription factor XE12/XE47 , class A basic helix-loop-helix transcription factor G12 , helix-loop-helix protein E12 , helix-loop-helix protein E47 , transcription factor 7-like 1 (T-cell specific, HMG-box) , transcription factor 7-like 1

664768 Danio rerio
6929 Homo sapiens
21423 Mus musculus
171046 Rattus norvegicus
379355 Xenopus laevis
395146 Gallus gallus
485079 Canis lupus familiaris
530616 Bos taurus
312451 Rattus norvegicus
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