anti-SHC3 (SHC3) 抗体产品概述

Full name:
anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 抗体 (SHC3)
在www.antibodies-online.cn可供57 SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) 抗体的16不同的供货商。 再加上,我们可以发SHC3 蛋白 (6)和数多这个蛋白质的别的产品。 总共70 SHC3产品已列进来了。
别名:
N-Shc, NSHC, Rai, ShcC

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引用最多的anti-SHC3 抗体

  1. Human Polyclonal SHC3 Primary Antibody for WB - ABIN2801960 : Liu, Meakin: ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 references for 2801960

  2. Human Monoclonal SHC3 Primary Antibody for IF, IP - ABIN968082 : Conti, Sipione, Magrassi, Bonfanti, Rigamonti, Pettirossi, Peschanski, Haddad, Pelicci, Milanesi, Pelicci, Cattaneo: Shc signaling in differentiating neural progenitor cells. in Nature neuroscience 2001 (PubMed)
    Show all 3 references for 968082

  3. Human Polyclonal SHC3 Primary Antibody for IHC, ELISA - ABIN1535370 : Nakamura, Sanokawa, Sasaki, Ayusawa, Oishi, Mori: N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway. in Oncogene 1996 (PubMed)
    Show all 2 references for 1535370

  4. Cow (Bovine) Polyclonal SHC3 Primary Antibody for WB - ABIN2786992 : Villanacci, Bassotti, Ortensi, Fisogni, Cathomas, Maurer, Galletti, Salerni, Pelicci: Expression of the Rai (Shc C) adaptor protein in the human enteric nervous system. in Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2008 (PubMed)

更多抗SHC3的相互作用对抗体

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

  1. High SHC3 expression is associated with glioblastoma.

  2. Rai (ShcC/N-Shc), a member of the family of Shc (显示 SHC1 抗体)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.

  3. Polymorphism in RAI (显示 RNH1 抗体) and CD3EAP (显示 CD3EAP 抗体) are associated with outcome of myeloma patients treated with high dose treatment.

  4. amplification of SHC3 and EDG3 (显示 S1PR3 抗体) genes suggests that the two proteins co-operate and are important for ependymomas in vivo.

  5. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (显示 SHC1 抗体).

  6. ALK (显示 ALK 抗体)-ShcC signal activation, possibly caused by co-amplification with the N-myc (显示 MYCN 抗体) gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK (显示 ALK 抗体) kinase.

  7. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret (显示 RET 抗体) to the phosphatidylinositol 3-kinase/Akt (显示 AKT1 抗体) signaling pathway.

  8. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (显示 ARHGEF16 抗体) cells

  9. The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells.

  10. data suggest that RAI (ShcC/H-Shc (显示 SHC1 抗体))is a critical substrate for RET (显示 RET 抗体) oncoproteins in thyroid carcinomas

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

  1. The results provide evidence that Rai/ShcC plays opposite roles in Th17 cell differentiation and astrocyte activation

  2. Rai (ShcC/N-Shc), a member of the family of Shc (显示 SHC1 抗体)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.

  3. Rai interferes with the TCR signaling cascade one of the earliest steps--recruitment of the initiating kinase ZAP-70 (显示 ZAP70 抗体) to the phosphorylated subunit of the TCR/CD3 (显示 CD3E 抗体) complex.

  4. TrkB (显示 NTRK2 抗体)-mediated ERK1/2 (显示 MAPK1/3 抗体) activation is impaired in huntingtin (显示 HTT 抗体) knock-in striatal cells involves reduced p52 (显示 GTF2H4 抗体)/p46 (显示 POLDIP3 抗体) Shc (显示 SHC1 抗体) expression

  5. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (显示 SHC1 抗体).

  6. binds the Trk (显示 NTRK1 抗体) receptors in a phosphotyrosine-dependent manner via their N-terminal phosphotyrosine binding domain

  7. Rai has a functional neuroprotective role in brain injury, with possible implications in the treatment of stroke

  8. ShcC mediates TrkB (显示 NTRK2 抗体)-Ras/MAPK (显示 MAPK1 抗体) signaling & regulates NMDA receptor function in the hippocampus via interaction with phosphotyrosines on the receptor subunits. It serves as a modulator of hippocampal synaptic plasticity underlying learning & memory.

  9. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (显示 ARHGEF16 抗体) cells

  10. Expressed in T and B cells; loss of Rai results in breaking of immunological tolerance and development of systemic autoimmunity.

SHC3 抗原简介

Antigen Summary

may be involved in brain-derived neurotrophic factor signalling during retinal development

Alternative names and synonyms associated with SHC3

  • SHC (Src homology 2 domain containing) transforming protein 3 (SHC3) 抗体
  • SHC (Src homology 2 domain containing) transforming protein 3 (Shc3) 抗体
  • src homology 2 domain-containing transforming protein C3 (Shc3) 抗体
  • N-Shc 抗体
  • NSHC 抗体
  • Rai 抗体
  • ShcC 抗体

Protein level used designations for SHC3

SH2 domain protein C3 , SHC-transforming protein 3 , SHC-transforming protein C , neuronal Shc , protein Rai , src homology 2 domain-containing transforming protein C3 , src homology 2 domain-containing-transforming protein C3 , N-Shc

GENE ID SPECIES
100061926 Equus caballus
53358 Homo sapiens
114858 Rattus norvegicus
476352 Canis lupus familiaris
20418 Mus musculus
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