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Human CXCL12 ELISA Kit for Sandwich ELISA - ABIN414920
Patschan, Patschan, Temme, Korsten, Wessels, Koziolek, Henze, Müller: Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD). in Critical care 2011
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Mouse (Murine) CXCL12 ELISA Kit for Sandwich ELISA - ABIN625176
Shirozu, Nakano, Inazawa, Tashiro, Tada, Shinohara, Honjo: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. in Genomics 1996
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Human CXCL12 ELISA Kit for Sandwich ELISA - ABIN625084
Gravina, Mancini, Ranieri, Di Pasquale, Marampon, Di Clemente, Ricevuto, Festuccia: Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples. in International journal of oncology 2013
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Rat (Rattus) CXCL12 ELISA Kit for Sandwich ELISA - ABIN416336
Tong, Xu, Han, Chen, Yang, Qiao, Hong, Wu, Zhou et al.: Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia ... in Phytomedicine : international journal of phytotherapy and phytopharmacology 2011
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Mouse (Murine) CXCL12 ELISA Kit for Sandwich ELISA - ABIN415535
Shi, Wang, Zhang, Cai, Zhou, Hou, van Rooijen: Monocyte/macrophages promote vasculogenesis in choroidal neovascularization in mice by stimulating SDF-1 expression in RPE cells. in Graefe's archive for clinical and experimental ophthalmology 2011
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Together, these data indicate that different mechanisms govern the flow response across GSCs, but that within a single patient, there are subpopulations of GSCs that respond to flow via either CD44 (显示 CD44 ELISA试剂盒)- or CXCR4 (显示 CXCR4 ELISA试剂盒)-CXCL12 mechanisms.
Data indicate that a constitutively monomeric CXCL12 variant reproduced the G protein-dependent and beta-arrestin-dependent responses that are associated with normal CXCR4 (显示 CXCR4 ELISA试剂盒) signaling and lead to cell migration.
HS had no effects on the binding of CXCL12alpha to CXCR4 (显示 CXCR4 ELISA试剂盒) or its biological activity, suggesting that this polysaccharide controls CXCL12 in an isoform-specific manner.
The level of CXCR4 (显示 CXCR4 ELISA试剂盒) protein expression was significantly higher in all cellular compartments of the endometriotic lesions compared to control endometrium. CXCL12 protein expression was also higher in endometriotic lesions and was greatest in the epithelial compartment. CXCL12 was increased more in the condition media of cultured endometriosis than in controls as measured by ELISA.
CCR1 activation potently induces multiple myeloma PC migration toward CCL3 (显示 CCL3 ELISA试剂盒) while abrogating the multiple myeloma PC migratory response to CXCL12.
High CXCL12 expression is associated with gemcitabine resistance in pancreatic cancer.
CXCL12 expression may be a useful marker for predicting the outcome in patients with esophageal squamous cell carcinoma and is a potentially new therapeutic target
our findings indicate the functional role of HBx in regulating the stem-like properties of OV6(+) CSCs in HCC (显示 FAM126A ELISA试剂盒) through the MDM2 (显示 MDM2 ELISA试剂盒)/CXCL12/CXCR4 (显示 CXCR4 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) signaling axis, and identify HBx, MDM2 (显示 MDM2 ELISA试剂盒), CXCR4 (显示 CXCR4 ELISA试剂盒) and OV6 as a novel prognostic pathway and potential therapeutic targets for patients with HBV-related HCC (显示 FAM126A ELISA试剂盒) patients
study revealed that the CXCL12-CXCR4 (显示 CXCR4 ELISA试剂盒) interaction is crucial for stromal cell contact-mediated early B lymphoid and pDC (显示 PNKD ELISA试剂盒) differentiation from immature hematopoietic and early T lymphoid precursors with a multilineage differentiation potential but not for stromal cell contact-independent generation of early T lymphoid precursors.
SDF-1, CXCR4 (显示 CXCR4 ELISA试剂盒) ligand, was highly expressed in mesenchymal stem cells when co-cultured with degenerated nucleus pulposus cells. Inhibition of SDF-1 using CXCR4 (显示 CXCR4 ELISA试剂盒) antagonist AMD3100 abolished the MSCs-induced decrease in the mechanical moduli and increased biological activity of degenerated NPCs, suggesting a crucial role for SDF-1/CXCR4 (显示 CXCR4 ELISA试剂盒) signaling.
these results demonstrate that a cross-talk exists between the TGF-beta1 (显示 TGFB1 ELISA试剂盒) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (显示 CXCR4 ELISA试剂盒) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (显示 CXCR7 ELISA试剂盒)/CXCR4 (显示 CXCR4 ELISA试剂盒)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
endothelial CXCR7 (显示 CXCR7 ELISA试剂盒)+ cells regulate CXCL12 gradient direction by controlling concentrations near but not far from the vasculature.
This study showed that release of BMP-2 (显示 BMP2 ELISA试剂盒) and SDF-1alpha from heparinized MCM scaffolds allows for the reduction of the applied BMP-2 (显示 BMP2 ELISA试剂盒) concentration since SDF-1alpha seems to enhance the osteoinductive potential of BMP-2 (显示 BMP2 ELISA试剂盒).
The results of this study suggested that enhanced interaction between STAT3 (显示 STAT3 ELISA试剂盒) and p300 (显示 NOTCH1 ELISA试剂盒) mediated the epigenetic upregulation of CXCL12 in dorsal horn neurons, which contributed to the antitubulin chemotherapeutics-induced persistent pain
Dipeptidyl peptidase-4 (显示 DPP4 ELISA试剂盒) inhibition, independent of glucagon-like peptide-1 receptor (显示 GLP1R ELISA试剂盒) signaling, contributes to protection of the diabetic kidney through SDF-1-dependent antioxidative and antifibrotic effects and amelioration of adverse renal hemodynamics.
High Cxcl12 expression is associated with Prostate Cancer.
Authors demonstrate that targeting the SDF-1/CXCR4 pathway in the context of KLF10 deletion substantially suppresses PDAC progression
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (显示 CXCR4 ELISA试剂盒) signalling pathway.
these findings demonstrate that expression of Hmga2 cooperates with Jak2 (显示 JAK2 ELISA试剂盒)(V617F) in the pathogenesis of Mmyelofibrosis.
Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (显示 CXCR7 ELISA试剂盒), while, in the presence of TGFbeta (显示 TGFB1 ELISA试剂盒), this CXCL12 effect of MSCs on tumour cells is relieved.
CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (显示 CCL1 ELISA试剂盒) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (显示 CXCR4 ELISA试剂盒) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (显示 CXCR4 ELISA试剂盒) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (显示 MYLIP ELISA试剂盒)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (显示 CCL1 ELISA试剂盒) signaling and Vegfc (显示 VEGFC ELISA试剂盒)-Flt4 (显示 FLT4 ELISA试剂盒) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (显示 CCL1 ELISA试剂盒) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (显示 CXCR7 ELISA试剂盒).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (显示 CXCR7 ELISA试剂盒)-mediated chemokine (显示 CCL1 ELISA试剂盒) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (显示 GATA4 ELISA试剂盒) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (显示 MYLIP ELISA试剂盒)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (显示 CXCR4 ELISA试剂盒) pair in brain development and functioning.
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, chemokine ligand 12
, unm t30516