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抗Human ROBO1 抗体:
抗Mouse (Murine) ROBO1 抗体:
抗Rat (Rattus) ROBO1 抗体:
Human Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN251549
Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. in PLoS genetics 2005
Mouse (Murine) Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN251688
Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. in Development (Cambridge, England) 2006
Human Polyclonal ROBO1 Primary Antibody for IP, IHC - ABIN1043879
Li, Wang, Chen, Liang: [Auditory neuropathy in children(analysis of 14 cases)]. in Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2005
Differential expression levels and methylation status of ROBO1 in mantle cell lymphoma and chronic lymphocytic leukaemia.
The alteration of Slit2 (显示 SLIT3 抗体) and Robo1 expression in the retinas of diabetic rats and patients with proliferative diabetic retinopathy suggests a role for the Slit-Robo signal in the various stages diabetic retinopathy.
Results demonstrate that human ROBO1 may be involved in the regulation of the structure and connectivity of posterior part of corpus callosum.
ROBO1 gene mutation is responsible for the development of pituitary stalk interruption syndrome.
human placental multipotent mesenchymal stromal cell express Slit2 (显示 SLIT3 抗体) and both Robo1 and Robo4 (显示 ROBO4 抗体) are present in human umbilical vein endothelial cells.
Slit2 (显示 SLIT3 抗体)-Robo1 signaling promoted the adhesion, invasion and migration of tongue carcinoma cells by upregulating the expression levels of MMP2 (显示 MMP2 抗体) and MMP9 (显示 MMP9 抗体) and, downregulating the expression of E-cadherin (显示 CDH1 抗体).
High Slit2 expression is associated with glioma.
ROBO1 mediated the inhibitory effect of miR (显示 MLXIP 抗体)-218 on angiogenesis in gastric cancer.
Results indicate the importance of SLIT2 (显示 SLIT3 抗体)-ROBO1-CDC42 (显示 CDC42 抗体) signaling pathway in predicting tumor progression.
We postulate that Robo1 promotes tumor invasion partly by the upregulation of MMP2 (显示 MMP2 抗体) after activation of PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) signaling pathway. Notably, Slit2 (显示 SLIT3 抗体) knockdown caused the upregulation of Robo1 expression both at the mRNA and protein levels. Thus, the stimulatory effects of Slit2 (显示 SLIT3 抗体) knockdown on tumor progression can be ascribed, at least in part, to the upregulation of Robo1 and its positive role in tumor progression.
Low Robo1 expression is associated with developmental defects of cranial frontal and parietal bones.
While Slit1 (显示 SLIT1 抗体) and Robo2 (显示 ROBO2 抗体) are only expressed in peripheral axons and their cell bodies, Slit2 (显示 SLIT2 抗体), Slit3 (显示 SLIT3 抗体) and Robo1 are also expressed in satellite cells of the dorsal root ganglion, Schwann cells and fibroblasts of peripheral nerves.
restoration of miR (显示 MLXIP 抗体)-218 inhibited retinal angiogenesis via targeting Robo1. MiR (显示 MLXIP 抗体)-218 contributed to the inhibition of retinal angiogenesis and miR (显示 MLXIP 抗体)-218 might be a new therapeutic target for preventing retinal neovascularization..
Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.
FLRT3 (显示 FLRT3 抗体) is a Robo1 coreceptor in developing axons.
Slit2 (显示 SLIT2 抗体)/Robo1 signaling promotes intestinal tumorigenesis through Src (显示 SRC 抗体)-mediated activation of the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway.
Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice
Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.
Slit2 (显示 SLIT2 抗体) signaling through Robo1 and Robo2 (显示 ROBO2 抗体) has a role in retinal neovascularization
Data indicate the roles of Slit1 (显示 SLIT1 抗体)/Robo1 and Netrin1/DCC (显示 DCC 抗体) signals in positioning motor neuron cell bodies.
Sox7 (显示 SOX7 抗体) and Sox18 (显示 SOX18 抗体)-mediated transcriptional regulation of Robo4 (显示 ROBO4 抗体) is important in the developing embryonic vasculature
robo4 (显示 ROBO4 抗体) is essential for coordinated symmetric and directed sprouting of intersomitic vessels.
Robo4 (显示 ROBO4 抗体) mediates attraction-signaling mechanisms through Rho GTPases in vertebrate vascular guidance
These results demonstrate a key role for Robo-Slit signaling in vertebrate longitudinal axon guidance; Robo1 and Robo3 (显示 ROBO3 抗体) restricted the extent of defasciculation of the tract of the postoptic commissure.
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
deleted in U twenty twenty
, roundabout homolog 1
, roundabout (axon guidance receptor, Drosophila) homolog 1
, roundabout, axon guidance receptor, homolog 1 (Drosophila)
, Roundabout1 protein
, roundabout 1
, roundabout, axon guidance receptor, homolog 1
, roundabout homolog 1-like
, magic roundabout
, divalent metal transporter-1
, protein RoBo-1
, rodent bone protein