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Mechanistic Target of Rapamycin (serine/threonine Kinase) ELISA试剂盒 (FRAP1)
在www.antibodies-online.cn可供45 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) ELISA试剂盒的14不同的供货商。 再加上,我们可以发MTOR 抗体 (368)MTOR 蛋白 (4)和数多这个蛋白质的别的产品。 总共432 MTOR产品已列进来了。
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08

适于 MTOR 相互作用对的更多 ELISA 试剂盒

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. High mTOR expression is associated with melanoma.

  2. Studies indicate that understanding mTOR network circuitry will provide insight into its deregulation in diabetes, cancer, and cardiovascular disease, but modeling in silico to elucidate how insulin (显示 INS ELISA试剂盒) activates mTORC2 (显示 CRTC2 ELISA试剂盒) remains poorly defined.

  3. Mutated MTOR identified in central nervous system germ cell tumors upregulated phosphorylation of the AKT (显示 AKT1 ELISA试剂盒) pathway proteins

  4. Findings demonstrate that the Akt (显示 AKT1 ELISA试剂盒)/mTOR pathway is upregulated in verrucous carcinoma of the oral cavity , indicating a role for this pathway in the development and progression of this malignancy.

  5. IL-37 regulates autophagy in SMMC-7721 and Huh-7 cells via inhibition of the PI3K (显示 PIK3CA ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒)/mTOR signaling pathway.

  6. A nutrient-sensitive mTOR/ChREBP (显示 MLXIPL ELISA试剂盒) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Interleukin-37 induces apoptosis and autophagy of SMMC-7721 cells by inhibiting phosphorylation of mTOR.

  8. Abnormal mTOR activity may contribute to chemotherapy resistance, while it may also be effectively targeted via molecular means and/or development of specific pharmacological inhibitors.

  9. CXCR2 (显示 CXCR2 ELISA试剂盒) preferentially supports the maintenance of human pluripotent stem cell characteristics as well as facilitates ectodermal differentiation after the commitment to differentiation, and the mechanism might be associated with mTOR, beta-catenin (显示 CTNNB1 ELISA试剂盒), and hTERT activities.

  10. Data show that mTOR protein forms a complex with Raptor (显示 RPTOR ELISA试剂盒) and estrogen receptor-alpha (ERalpha (显示 ESR1 ELISA试剂盒)).

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. results establish a novel mechanism by which mTORC1 regulates Th1 differentiation, through control of T-bet phosphorylation

  2. Tsc2 (显示 TSC2 ELISA试剂盒)-mTOR signaling in mesenchyme is essential for the maintenance of renal structure and for lung alveolarization.

  3. This study suggests that mTOR activity in hepatocytes decreases hepatic vulnerability to injury through a mechanism dependent on NF-kappaB (显示 NFKB1 ELISA试剂盒) proinflammatory cytokine signaling pathway in both normal and steatotic liver.

  4. TSC1 (显示 TSC1 ELISA试剂盒)/TSC2 (显示 TSC2 ELISA试剂盒) complex upregulation of OPN (显示 SPP1 ELISA试剂盒) expression is mediated by transcription factor SOX9 (显示 SOX9 ELISA试剂盒) in an mTOR-independent manner. Moreover, ablation of OPN (显示 SPP1 ELISA试剂盒) by deficient TSC1 (显示 TSC1 ELISA试剂盒)/TSC2 (显示 TSC2 ELISA试剂盒) complex contributed to inactivation of AKT (显示 AKT1 ELISA试剂盒) in TSC (显示 SLC12A3 ELISA试剂盒) cells

  5. Suppressing mTOR signaling in in vitro-expanded Vgamma4 gammadelta T cells via the mechanistic inhibitor rapamycin enhanced their cytotoxicity against multiple tumor cell lines, and these cells performed better tumor-suppressing effects upon adoptive therapy. mTOR signaling plays an important role in the cytotoxic effector function of gammadelta T cells.

  6. A nutrient-sensitive mTOR/ChREBP (显示 MLXIPL ELISA试剂盒) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Mycobacterium ulcerans mycolactone acts as an inhibitor of the mechanistic Target of Rapamycin (mTOR) signaling pathway by interfering with the assembly of the two distinct mTOR protein complexes mTORC1 and mTORC2 (显示 CRTC2 ELISA试剂盒)

  8. High mTOR expression is associated with pituitary tumor development.

  9. mTOR protein signaling promotes stable epidermal adhesion in the skin and accelerates wound healing.

  10. mTOR-sensitive perturbation of smooth muscle cell mechanosensing contributes to elastin (显示 ELN ELISA试剂盒) aortopathy.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (显示 ESCO2 ELISA试剂盒) cells and supports that normal gene expression and translation requires ESCO2 (显示 ESCO2 ELISA试剂盒) function.

  2. By inhibiting mTOR signaling via Fbxw7 (显示 FBXW7 ELISA试剂盒), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (显示 TP53 ELISA试剂盒).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR and PPARg (显示 PPARG ELISA试剂盒). In summary, PPARg (显示 PPARG ELISA试剂盒) plays an important role in the regulation of IGF-1 (显示 IGF1 ELISA试剂盒) secretion and gene expression in response to dietary protein.

  2. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 ELISA试剂盒)-mTOR-FOXO1 (显示 FOXO1 ELISA试剂盒) signaling and suppressing the activation of TLR4 (显示 TLR4 ELISA试剂盒) and/or NOD2 (显示 NOD2 ELISA试剂盒) signaling pathways.

  3. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  4. AMPK (显示 PRKAA1 ELISA试剂盒)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  5. Uroguanylin (显示 GUCA2B ELISA试剂盒) modulates (Na++K+)ATPase (显示 ATP1A1 ELISA试剂盒) in a proximal tubule cells via cGMP/protein kinase (显示 CDK7 ELISA试剂盒) G, cAMP/protein kinase A, and mTOR pathways.

  6. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (显示 CCND1 ELISA试剂盒), and CCNE1 (显示 CCNE1 ELISA试剂盒).

  7. L-Glutamine enhances enterocyte growth via activation of the mTOR.

  8. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr cells through activation of the MTOR-RPS6K-RPS6 (显示 RPS6 ELISA试剂盒)-EIF4EBP1 (显示 EIF4EBP1 ELISA试剂盒) signal transduction pathway.

  9. Data indicate that the expression of MAP1LC3A (显示 MAP1LC3A ELISA试剂盒), B and autophagy-associated genes (ATG5 (显示 ATG5 ELISA试剂盒), mTOR, Beclin-1 (显示 BECN1 ELISA试剂盒)) was increased in normal pigs, while decreased in miniature pigs.

  10. Biochemical, cellular, and molecular data suggest that L-arginine (显示 GATM ELISA试剂盒) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These findings suggest that mTOR is involved in the control of the expression of multiple genes in cattle, which may be triggered by the luteinizing hormone surge.

  2. 14-3-3gamma (显示 YWHAG ELISA试剂盒) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (显示 JAK2 ELISA试剂盒)-STAT5 (显示 STAT5A ELISA试剂盒) and mTOR signaling pathways.

  4. Insulin (显示 INS ELISA试剂盒)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  5. IGF-I (显示 IGF1 ELISA试剂盒) down-regulated functional IGF-I receptor (显示 IGF1R ELISA试剂盒) via GSK-3beta (显示 GSK3b ELISA试剂盒) inhibition and mTOR activation; constitutive activity of GSK-3beta (显示 GSK3b ELISA试剂盒) maintained IGF-I receptor (显示 IGF1R ELISA试剂盒) level in nonstimulated cells.

  6. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (显示 INS ELISA试剂盒), and prolactin (显示 PRL ELISA试剂盒) were associated with increased phosphorylation of the mTOR substrates

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (显示 AKT1 ELISA试剂盒), mTOR, p70S6K (显示 RPS6KB1 ELISA试剂盒), and ERK1/2 (显示 MAPK1/3 ELISA试剂盒).

  8. prostaglandin F2alpha phosphorylates TSC2 (显示 TSC2 ELISA试剂盒) and activates mTOR and ribosomal protein S6 (显示 RPS6 ELISA试剂盒) kinase (显示 RPS6KB1 ELISA试剂盒) signaling in an AKT (显示 AKT1 ELISA试剂盒)-independent manner

  9. mTOR links IGF-I (显示 IGF1 ELISA试剂盒) and EGF (显示 EGF ELISA试剂盒) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) Elisa Kit
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) Elisa Kit
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) Elisa Kit
  • 2610315D21Rik Elisa Kit
  • AI327068 Elisa Kit
  • flat Elisa Kit
  • FRAP Elisa Kit
  • frap1 Elisa Kit
  • FRAP2 Elisa Kit
  • RAFT1 Elisa Kit
  • RAPT1 Elisa Kit
  • tor Elisa Kit
  • wu:fc22h08 Elisa Kit

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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