GTPase NRas (NRAS) ELISA试剂盒产品概述

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GTPase NRas ELISA试剂盒 (NRAS)
在www.antibodies-online.cn可供6 GTPase NRas (NRAS) ELISA试剂盒的2不同的供货商。 再加上,我们可以发GTPase NRas 抗体 (102)GTPase NRas 蛋白 (17)和数多这个蛋白质的别的产品。 总共130 GTPase NRas产品已列进来了。
别名:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

适于 GTPase NRas 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. loss of one allele of Hras (显示 HRAS ELISA试剂盒) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (显示 HRAS ELISA试剂盒) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (显示 HRAS ELISA试剂盒), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (显示 EZH2 ELISA试剂盒) or Eed (显示 EED ELISA试剂盒) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (显示 WNT2 ELISA试剂盒) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 and PTEN

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (显示 RUNX1 ELISA试剂盒) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (显示 RUNX1 ELISA试剂盒) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (显示 CBFB ELISA试剂盒)-SMMHC (显示 MYH11 ELISA试剂盒) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (显示 MDK ELISA试剂盒)/ERK (显示 EPHB2 ELISA试剂盒)/Bim (显示 BCL2L11 ELISA试剂盒) axis, and define Nras(LSL-G12D); Cbfb (显示 CBFB ELISA试剂盒)(56M) mice as a valuable genetic model for the study of AML (显示 RUNX1 ELISA试剂盒) therapies.

Human GTPase NRas (NRAS) interaction partners

  1. NRAS mutations were present in 1.2% of primary papillary thyroid carcinomas, 1.3% of lymph node metastasis, and 14.3% of distant metastasis.

  2. Data suggest that isoform-specific sequences in the allosteric lobes of HRAS (显示 HRAS ELISA试剂盒), KRAS, and NRAS have an impact on biocatalysis (kinetics of GTP (显示 AK3 ELISA试剂盒) hydrolysis) and interaction with c-Raf (显示 RAF1 ELISA试剂盒) kinase, which must be due to allosteric effects on dynamics and conformational states, given the identical active sites of these isoenzymes.

  3. NRAS(Q61R) immunohistochemistry is a highly sensitive and specific tool that is useful for differentiating follicular-patterned thyroid tumors.

  4. NRAS variants were identified in 2 cases with a lethal presentation of Noonan syndrome.

  5. Mutation in NRAS gene is associated with chronic myelomonocytic leukemia.

  6. Compared with newly diagnosed multiple myeloma, an increased prevalence of mutations in the Ras pathway genes KRAS, NRAS, and/or BRAF (显示 BRAF ELISA试剂盒) (72%), as well as TP53 (显示 TP53 ELISA试剂盒) (26%), CRBN (显示 CRBN ELISA试剂盒) (12%), and CRBN (显示 CRBN ELISA试剂盒) pathway genes (10%) was observed.

  7. Our data suggest that testing for any RAS mutation is unlikely to change the clinical management of thyroid nodules that have indeterminate cytology

  8. Examination of clinical parameters of these tumors found those with APA (显示 ENPEP ELISA试剂盒) of NRAS and c-JUN (显示 JUN ELISA试剂盒) to be smaller and less proliferative

  9. Equilibrium dissociation constants were determined for the binding of HRAS, KRAS, NRAS and RRAS2 to the RAS binding (RB) domain of binding proteins.

  10. Studies indicate that RAS proteins were among the first oncogenes identified and are mutationally activated in 30% of all cancer types.

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (显示 TP53 ELISA试剂盒) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) 抗原简介

Antigen Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) Elisa Kit
  • African clawed frog N-ras (n-ras) Elisa Kit
  • neuroblastoma ras oncogene (Nras) Elisa Kit
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) Elisa Kit
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) Elisa Kit
  • ALPS4 Elisa Kit
  • AV095280 Elisa Kit
  • fj99a10 Elisa Kit
  • H-RAS Elisa Kit
  • HRAS Elisa Kit
  • N-RAS Elisa Kit
  • NRAS Elisa Kit
  • NRAS1 Elisa Kit
  • NS6 Elisa Kit
  • wu:fj99a10 Elisa Kit
  • zgc:100761 Elisa Kit
  • zras-b1 Elisa Kit

Protein level used designations for GTPase NRas (NRAS) ELISA试剂盒

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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