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ADAM17 (ADAM17) ELISA试剂盒产品概述

Full name:
ADAM Metallopeptidase Domain 17 ELISA试剂盒 (ADAM17)
在www.antibodies-online.cn可供33 ADAM Metallopeptidase Domain 17 (ADAM17) ELISA试剂盒的13不同的供货商。 再加上,我们可以发ADAM17 抗体 (262)ADAM17 蛋白 (15)和数多这个蛋白质的别的产品。 总共319 ADAM17产品已列进来了。
别名:
adam17, ADAM18, CD156B, CSVP, NISBD, si:dkey-81b15.2, Tace

引用最多的ADAM17 ELISA试剂盒

  1. ABIN1882558 : Cardellini, Menghini, Martelli, Casagrande, Marino, Rizza, Porzio, Mauriello, Solini, Ippoliti, Lauro, Folli, Federici: TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. in Diabetes 2009 (PubMed)
    Show all 33 references for ABIN1882558

  2. Mouse (Murine) ADAM17 ELISA Kit for Sandwich ELISA - ABIN810367 : Lagrange, Li, Fassot, Bourhim, Louis, Nguyen Dinh Cat, Parlakian, Wahl, Lacolley, Jaisser, Regnault: Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 (PubMed)

  3. Human ADAM17 ELISA Kit for Sandwich ELISA - ABIN415265 : Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. in International wound journal 2016 (PubMed)

适于 ADAM17 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Suggest an atheroprotective role of ADAM17, which might be mediated by cleaving membrane-bound TNFalpha (显示 TNF ELISA试剂盒) and TNFR2 (显示 TNFRSF1B ELISA试剂盒), thereby preventing overactivation of endogenous TNFR2 (显示 TNFRSF1B ELISA试剂盒) signaling in cells of the vasculature.

  2. Aging and obesity cooperatively reduce caveolin-1 (显示 CAV1 ELISA试剂盒) expression and increase vascular endothelial ADAM17 activity and soluble TNF (显示 TNF ELISA试剂盒) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  3. Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10 (显示 ADAM10 ELISA试剂盒)/17 and intramembrane protease gamma-secretase.

  4. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (显示 AXL ELISA试剂盒)kinase (Axl) in lupus-prone leukocytes.

  5. These findings suggest that maintaining ADAM17-EGFR (显示 EGFR ELISA试剂盒) epithelial signaling is necessary for the recovery from UC and would be beneficial to therapeutic strategies targeting ADAM17-mediated TNF-a (显示 TNF ELISA试剂盒) shedding.

  6. Data show that caveolin 1 (CAV1 (显示 CAV1 ELISA试剂盒)) is required for transforming growth factor-beta (TGF-beta)-induced reactive oxygen species production, mediated by NADPH oxidase (显示 NOX1 ELISA试剂盒) NOX1 (显示 NOX1 ELISA试剂盒), that is necessary for a disintegrin and metalloproteinase 17 (ADAM17) activation.

  7. ADAM12 (显示 ADAM12 ELISA试剂盒) and ADAM17 are essential molecules for the impairment of barrier function of retinal vasculature under hypoxia.

  8. 4-Hydroxyisoleucine improved insulin (显示 INS ELISA试剂盒) resistant-like state in 3T3-L1 adipocytes by targeting TACE/TIMP3 (显示 TIMP3 ELISA试剂盒) and the insulin (显示 INS ELISA试剂盒) signaling pathway.

  9. Hypercapnic acidosis blocks stretch-mediated activation of ADAM17. ADAM17 is an important proximal mediator of ventilator-induced lung injury.

  10. Lrig2 has a role in negative regulation of ectodomain shedding of axon guidance receptors by ADAM17 protease

Human ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Cell stimulation can downregulate expression of mature ADAM17 from the cell surface and induce release of exosomal ADAM17, which can then distribute and contribute to substrate shedding on more distant cells.

  2. Aging and obesity cooperatively reduce caveolin-1 (显示 CAV1 ELISA试剂盒) expression and increase vascular endothelial ADAM17 activity and soluble TNF (显示 TNF ELISA试剂盒) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  3. Our data demonstrated that elevated serum Semaphorin5A (Sema5A (显示 SEMA5A ELISA试剂盒)) in SLE patients correlated with disease activity and are involved in kidney and blood system damage; ADAM17 might be involved in the release of secreted Sema5A (显示 SEMA5A ELISA试剂盒).

  4. ADAM17 and ADAM10 (显示 ADAM10 ELISA试剂盒) cleave Nectin-4 (显示 PVRL4 ELISA试剂盒) and release soluble Nectin-4 (显示 PVRL4 ELISA试剂盒) (sN4).

  5. ADAM17 promotes epithelial-mesenchymal transition via the TGF-beta (显示 TGFB1 ELISA试剂盒)/Smad (显示 SMAD1 ELISA试剂盒) pathway. the present study demonstrates that ADAM17 plays a critical role in the development of gastric cancer and provides a potential therapeutic target for gastric cancer.

  6. FHL2 (显示 FHL2 ELISA试剂盒) interacts with ADAM-17 in normal, dysplastic and malignant colon epithelial cells. Colocalisation of these proteins is more frequent in malignant than in normal and dysplastic cells, suggesting a role for ADAM-17/FHL2 (显示 FHL2 ELISA试剂盒) complex in the development of colorectal cancer.

  7. The present study suggests that ADAM17-siRNA inhibits MCF-7 breast cancer and is activated through the EGFR (显示 EGFR ELISA试剂盒)-PI3K (显示 PIK3CA ELISA试剂盒)-AKT (显示 AKT1 ELISA试剂盒) signaling pathway

  8. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (显示 AXL ELISA试剂盒)) is rescued by combined matrix metalloproteases ADAM10 (显示 ADAM10 ELISA试剂盒) and TACE (ADAM17) inhibition.

  9. the TLR4 (显示 TLR4 ELISA试剂盒)/Gal-1 (显示 LGALS1 ELISA试剂盒) signaling pathway regulates lactate-mediated EMT (显示 ITK ELISA试剂盒) processes through the activation of ADAM10 (显示 ADAM10 ELISA试剂盒) and ADAM17 in colon cancer cells.

  10. The HNE-TACE signalling pathway has an important role in the process of MUC5AC overexpression in chronic rhinosinusitis.

Pig (Porcine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. ADAM17 was involved in porcine CD16 (显示 CD16 ELISA试剂盒) shedding in porcine reproductive and respiratory syndrome virus-infected pigs.

  2. Overexpression of ADAM17 induced downregulation of CD163 (显示 CD163 ELISA试剂盒) expression and a reduction in reproductive and respiratory syndrome virus infection.

  3. activation of TACE/ADAM17 via a PKC (显示 FYN ELISA试剂盒)-induced c-Src (显示 SRC ELISA试剂盒)-dependent manner mediates proteolytic activation of the EGF (显示 EGF ELISA试剂盒)-like factors that are involved in the induction of granulosa cell differentiation, cumulus expansion, and meiotic maturation of porcine oocytes

  4. Data indicate that TNF-alpha (显示 TNF ELISA试剂盒) stimulates Rac (显示 AKT1 ELISA试剂盒), ADAM17/TACE, and RhoA (显示 RHOA ELISA试剂盒) through the guanine nucleotide exchange factor (显示 ARHGEF12 ELISA试剂盒) (GEF)-H1 (显示 ARHGEF2 ELISA试剂盒).

  5. progesterone-induced TACE/ADAM17 leads to production of soluble EGF (显示 EGF ELISA试剂盒) domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes

ADAM17 抗原简介

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway.

Alternative names and synonyms associated with ADAM17

  • ADAM metallopeptidase domain 17 (ADAM17) Elisa Kit
  • a disintegrin and metallopeptidase domain 17b (adam17b) Elisa Kit
  • ADAM metallopeptidase domain 17 (adam17) Elisa Kit
  • a disintegrin and metallopeptidase domain 17 (Adam17) Elisa Kit
  • ADAM metallopeptidase domain 17 (Adam17) Elisa Kit
  • adam17 Elisa Kit
  • ADAM18 Elisa Kit
  • CD156B Elisa Kit
  • CSVP Elisa Kit
  • NISBD Elisa Kit
  • si:dkey-81b15.2 Elisa Kit
  • Tace Elisa Kit

Protein level used designations for ADAM17

ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) , a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) , disintegrin and metalloproteinase domain-containing protein 17 , tumor necrosis factor alpha converting enzyme , a disintegrin and metallopeptidase domain 17 , ADAM metallopeptidase domain 17 , a disintegrin and metalloprotease domain 17 , disintegrin metalloproteinase , disintegrin and metalloproteinase domain-containing protein 17-like , ADAM 17 , TNF-alpha convertase , TNF-alpha converting enzyme , TNF-alpha-converting enzyme , a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme , a disintegrin and metalloproteinase domain 17 , ADAM metallopeptidase domain 18 , snake venom-like protease , tumor necrosis factor, alpha, converting enzyme

GENE ID SPECIES
421931 Gallus gallus
459018 Pan troglodytes
560657 Danio rerio
694429 Macaca mulatta
733430 Xenopus laevis
100072496 Equus caballus
100406520 Callithrix jacchus
100482770 Ailuropoda melanoleuca
11491 Mus musculus
6868 Homo sapiens
57027 Rattus norvegicus
475662 Canis lupus familiaris
397343 Sus scrofa
517541 Bos taurus
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