anti-EGFR (EGFR) 抗体产品概述

Full name:
anti-Epidermal Growth Factor Receptor 抗体 (EGFR)
在www.antibodies-online.cn可供2360 Epidermal Growth Factor Receptor (EGFR) 抗体的43不同的供货商。 再加上,我们可以发EGFR 试剂盒 (145)EGFR 蛋白 (136)和数多这个蛋白质的别的产品。 总共2714 EGFR产品已列进来了。
别名:
9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, dEgfr, dEGFR1, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, Egf-r, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, top, top/DER, top/flb, Torpedo/DER, torpedo/egfr, wa-2, wa2, Wa5

所有可销售的anti-EGFR 抗体

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引用最多的anti-EGFR 抗体

  1. Human Polyclonal EGFR Primary Antibody for EIA - ABIN358328 : Aifa, Aydin, Nordvall, Lundström, Svensson, Hermanson: A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. in Experimental cell research 2004 (PubMed)
    Show all 5 references for 358328

  2. Human Polyclonal EGFR Primary Antibody for WB - ABIN391933 : Kuribayashi, Kataoka, Kurabayashi, Miura: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. in Endocrinology 2004 (PubMed)
    Show all 3 references for 391933

  3. Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN389891 : Kapoor, Zhan, Johnson, ORourke: Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for 389891

  4. Human Polyclonal EGFR Primary Antibody for ELISA, WB - ABIN1532008 : Ullrich, Coussens, Hayflick, Dull, Gray, Tam, Lee, Yarden, Libermann, Schlessinger: Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. in Nature 1984 (PubMed)

  5. Dog (Canine) Monoclonal EGFR Primary Antibody for EIA, IF - ABIN126767 : Kondo, Higa-Nakamine, Maeda, Toku, Kakinohana, Sugahara, Kukita, Yamamoto: Stimulation of Cell Migration by Flagellin Through the p38 MAP Kinase Pathway in Cultured Intestinal Epithelial Cells. in Journal of cellular biochemistry 2015 (PubMed)

  6. Human Polyclonal EGFR Primary Antibody for FACS, IHC (p) - ABIN651628 : Lowenstein, Daly, Batzer, Li, Margolis, Lammers, Ullrich, Skolnik, Bar-Sagi, Schlessinger: The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. in Cell 1992 (PubMed)

  7. Human Monoclonal EGFR Primary Antibody for FACS, IF - ABIN452102 : Wikstrand, Hale, Batra, Hill, Humphrey, Kurpad, McLendon, Moscatello, Pegram, Reist: Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. in Cancer research 1995 (PubMed)

  8. Human Monoclonal EGFR Primary Antibody for IHC (p) - ABIN1687358 : Krager, Sarkar, Twait, Lill, Koland: A novel biotinylated lipid raft reporter for electron microscopic imaging of plasma membrane microdomains. in Journal of lipid research 2012 (PubMed)

更多抗EGFR的相互作用对抗体

Horse (Equine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Results indicated that most periocular squamous cell carcinomas of horses expressed epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2 (显示 ERBB2 抗体)).

Fruit Fly (Drosophila melanogaster) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. The activity of Gro (显示 CXCL1 抗体) is antagonized by EGFR signaling, which inhibits Gro (显示 CXCL1 抗体)-dependent repression via p-ERK (显示 MAPK1 抗体) mediated phosphorylation.

  2. These results reveal that ESCRT-0 (ESCRT-0 components stam (显示 STAM 抗体) and hrs)mutants inhibit EGFR signaling by disrupting Rhomboid endosomal trafficking in the ligand-producing cells.

  3. we find that EGFR regulates the apical determinant Crb and the extracellular matrix regulator Serp, two factors previously known to control tube length. EGFR regulates the organisation of endosomes in which Crb and Serp proteins are loaded

  4. Here we uncover a cell non-autonomous requirement for the Epidermal growth factor receptor (Egfr) pathway in the lateral epidermis for sustained dpp (显示 TGFb 抗体) expression in the LE. Specifically, we demonstrate that Egfr pathway activity in the lateral epidermis prevents expression of the gene scarface (scaf), encoding a secreted antagonist of JNK (显示 MAPK8 抗体) signaling

  5. Loss of Usp5 (显示 USP5 抗体) results in upregulation of Notch (显示 NOTCH1 抗体) signaling and downregulation of RTK signaling by EGF receptor (EGFR) and Sevenless (Sev), leading to impaired photoreceptor development.

  6. These data demonstrate a strong genetic link between dG9a and the EGFR signaling pathway.

  7. Avermectin directly interacts with EGFR and leads to the activation of the EGFR/AKT (显示 AKT1 抗体)/ERK (显示 MAPK1 抗体) pathway.

  8. The dorsoventral patterning and EGFR signaling genes play essential roles in correct identity determination and differentiation of lateral glia in the Drosophila nervous system.

  9. Data suggest that OSCP1 (organic solute carrier partner 1 (显示 OSCP1 抗体)) plays multiple roles during eye development in D. melanogaster; OSCP1 (显示 OSCP1 抗体) regulates developmental gene expression and epidermal growth factor receptor signaling pathway in imaginal discs of eye.

  10. The vector of cell movement is regulated by localised epidermal growth factor (EGF (显示 EGF 抗体)) signalling from the distally placed tip cell lineage and the acquisition of planar polarity leads to asymmetric pulsatile Myosin II accumulation.

Zebrafish Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Study demonstrated that IGF-I (显示 IGF1 抗体) can stimulate egfr expression in both follicles cell culture and intact follicles promoting oocyte maturation.

  2. These results indicate that maintenance of Pgrmc1 (显示 PGRMC1 抗体) signaling is required for Egfr expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr in maintaining meiotic arrest through estrogen activation of Gper (显示 GPER 抗体).

  3. EGFR signaling in vertebrate oocytes can prevent meiotic progression.

  4. the expression of EGFR was mainly restricted to the follicle cells with little expression in the oocytes

Human Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. EGFR and C/EBP-beta (显示 CEBPB 抗体) oncogenic signaling is bidirectional in human glioma and varies with the C/EBP-beta (显示 CEBPB 抗体) isoform

  2. Studies indicate that positive PD-L1 (显示 CD274 抗体) expression was significantly correlated with KRAS mutation and EGFR mutation.

  3. Piccolo (显示 PCLO 抗体) contributes to tumor aggressiveness in esophageal squamous cell carcinoma, likely by stabilizing EGFR and promoting EGFR-dependent signaling.

  4. Finally, the authors show that EGFR-ERK1/2 (显示 MAPK1/3 抗体) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 (显示 EGR1 抗体) upregulation.

  5. Two new signals were observed at genome-wide significance (P < 5 x 10-8), namely, rs7216064 (17q24.3, BPTF (显示 BPTF 抗体)), for overall lung adenocarcinoma risk, and rs3817963 (6p21.3, BTNL2 (显示 BTNL2 抗体)) which is specific to cases with EGFR mutations. In further sub-analyses by EGFR status, rs9387478 (ROS1 (显示 ROS1 抗体)/DCBLD1) and rs2179920 (HLA-DPB1 (显示 HLA-DPB1 抗体)) showed stronger estimated associations in EGFR-positive compared to EGFR-negative cases

  6. Study shows that EGFR negatively regulates POPDC1 (显示 BVES 抗体) expression in breast cancer cell lines and that overexpression of POPDC1 (显示 BVES 抗体) can reduce EGFR-mediated cell migration and proliferation in breast cancer cells.

  7. The present findings indicate that genetic variation in EGFR may contribute to the attainment of extreme old age in Japanese.

  8. developed a simulator to accurately calculate the dynamic sensitivity of extracellular-signal-regulated kinase (ERK (显示 EPHB2 抗体)) activity (ERK (显示 EPHB2 抗体)*) and Akt (显示 AKT1 抗体) activity (Akt (显示 AKT1 抗体)*), downstream of the ErbB receptors stimulated with epidermal growth factor (EGF (显示 EGF 抗体)) and heregulin (HRG (显示 NRG1 抗体))

  9. EGFR amplification/EGFRvIII mutation can repress the expression of Pri-miR (显示 MLXIP 抗体)-524 by histone modification. MiR (显示 MLXIP 抗体)-524-3p and miR (显示 MLXIP 抗体)-524-5p inhibited TGF/beta (显示 TGFB1 抗体), Notch (显示 NOTCH1 抗体) and the Hippo pathway by targeting Smad2 (显示 SMAD2 抗体), Hes1 and Tead1 (显示 TEAD1 抗体), respectively; these pathways repressed their common downstream transcription factor, C-myc (显示 MYC 抗体).

  10. The searched for functional interactions between EGFR and D2-like receptors, focusing on the molecular mechanisms involved in the EGFR-mediated regulation of dopamine receptor signaling.

Mouse (Murine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. EGFR signaling in macrophages, but not in colonic epithelial cells, has a significant role in colitis-associated carcinogenesis.

  2. KrasG12D-driven proliferation of pancreatic ductal epithelial cells (PDECs) depends on an EGFR signaling loop engaging the oncogenic transcription factor c-MYC (显示 MYC 抗体).

  3. Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

  4. High expression of EGFR is associated with lung carcinogenesis.

  5. our results suggest that NeuGcGM3 and EGFR may coordinately contribute to the tumor cell biology and that therapeutic combinations against these two targets might be a valid strategy to explore.

  6. In FGF9-overexpressing colorectal cancer cell lines, FGF9 overexpression induced strong resistance to anti-EGFR therapies via the enforced FGFR (显示 FGFR2 抗体) signal, and this resistance was cancelled by the application of an FGFR (显示 FGFR2 抗体) inhibitor.

  7. Although EGFR activation promotes wound healing, released exosomes may antagonize EGFR activation and wound healing.

  8. opposing signals generated by different ErbB dimer combinations function in the same cardiac cushion mesenchymal cells for proper cardiac valve formation.

  9. Combined targeting of TGF-beta (显示 TGFB1 抗体), EGFR and HER2 (显示 ERBB2 抗体) signaling suppresses lymphangiogenesis and metastasis in a pancreatic ductal adenocarcinoma model.

  10. The conjugation of benzylguanine-modified auristatin F to EGFR-specific 425(scFv)-SNAP and HER2 (显示 ERBB2 抗体)-specific alphaHER2(scFv)-SNAP resulted in two potent recombinant antibody-drug conjugates that specifically killed breast cancer cell lines by inducing apoptosis when applied at nanomolar concentrations.

Pig (Porcine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. this study shows that anemonin may ameliorate LPS (显示 IRF6 抗体)-induced intestinal injury and improve restoration by regulating the TGF-b1 and EGFR signaling pathways

  2. Syndecan-4 (显示 SDC4 抗体) mediates porcine respiratory and reproductive syndrome virus entry by interacting with EGFR.

  3. These results indicate that cAMP and oocyte-secreted factors cooperate to promote EGF receptor functionality in developing cumulus oocyte complexes, representing a key component of the acquisition of oocyte developmental competence.

  4. patients experiencing gefitinib dose reduction or short-term treatment interruption due to toxicities did not show inferior survival, compared to those receiving full dose of gefitinib in non-small cell lung cancer patients with EGFR mutation

  5. Report EGFR expression in the normal pancreas.

  6. Injury and activation of purinergic receptors and direct activation of EGFR via EGF (显示 EGF 抗体) induce distinct downstream pathways.

  7. Data suggest that the mechanism of hypoxia-induced increased activation of EGFR kinase is mediated by nNOS (显示 NOS1 抗体)-derived nitric oxide.

  8. EGFR, VEGFR (显示 KDR 抗体) and FGFR (显示 FGFR2 抗体) are expressed in porcine oviduct and endometrium during the time of implantation [review]

  9. the restricted presence of the functional full-size receptor to the epithelial layer indicates a specific role during early embryonic development, whereas truncated EGF-R forms may potentially regulate contractions and blood flow in the oviduct

  10. The phase-related expression of EGF (显示 EGF 抗体) and EGFR in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF (显示 EGF 抗体) and its receptor on the uterine artery and the region supplying these vessels.

Cow (Bovine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Stimulation of bovine oviduct epithelial cell EGFR with EGF (显示 EGF 抗体) (human recombinant EGF (显示 EGF 抗体)) alone or with EGF (显示 EGF 抗体) in postovulatory/follicular phases (not luteal phase) up-regulates phosphorylation of MAPKs; heat blocks effects of EGF (显示 EGF 抗体) on phosphorylation of MAPKs.

  2. Expression of the erbB/HER receptor family in the bovine uterus during the sexual cycle and the relation of this family to serum sex steroids.

  3. Regulation of the sperm EGFR by ouabain leads to initiation of the acrosome reaction.

  4. EGFR may simultaneously activate c-Src (显示 SRC 抗体) and PI3K to amplify the oxytocin signaling to increase the output of PGF (显示 PGF 抗体)(2 alpha) in endometrial epithelial cells.

  5. results indicate that arginase induction depends in part on epidermal growth factor (EGF (显示 EGF 抗体)) receptor activity, and that EGFR inhibitors may attenuate vascular remodeling without affecting nitric oxide release

  6. Data suggest that epidermal growth factor (EGF (显示 EGF 抗体)) and EGF (显示 EGF 抗体) receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.

  7. MT1-MMP (显示 MMP14 抗体) has a role in signaling events mediating EGFR transactivation

  8. possible cooperative role of the EGF (显示 EGF 抗体) and HGF (显示 HGF 抗体) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

  9. EGFR is stimulated during capacitation via PKA activation. More activation induces the acrosome reaction, which is induced by GPCR via EGFR transactivation by a signaling pathway involving PKA, SRC & metalloproteinase & effectors PI3K, PLC & PKC.

EGFR 抗原简介

Antigen Summary

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with EGFR

  • epidermal growth factor receptor (EGFR) 抗体
  • Epidermal growth factor receptor (Egfr) 抗体
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) 抗体
  • epidermal growth factor receptor (egfr1) 抗体
  • epidermal growth factor receptor (AaeL_AAEL004319) 抗体
  • epidermal growth factor receptor (Egfr) 抗体
  • epidermal growth factor receptor (LOC100008806) 抗体
  • 9030024J15Rik 抗体
  • AI552599 抗体
  • C-erb 抗体
  • c-erbB 抗体
  • CG10079 抗体
  • D-Egf 抗体
  • d-egf-r 抗体
  • D-EGFR 抗体
  • dEgfr 抗体
  • dEGFR1 抗体
  • der 抗体
  • DER/EGFR 抗体
  • DER/faint little ball 抗体
  • DER/top 抗体
  • DER/torpedo 抗体
  • DER1 抗体
  • DER flb 抗体
  • Dmel\\CG10079 抗体
  • DmHD-33 抗体
  • EFG-R 抗体
  • Egf 抗体
  • Egf-r 抗体
  • egfr 抗体
  • egfr1 抗体
  • EGFR12 抗体
  • EGFR15 抗体
  • EK2-6 抗体
  • El 抗体
  • Elp 抗体
  • Elp-1 抗体
  • Elp-B1 抗体
  • Elp-B1RB1 抗体
  • Erbb 抗体
  • ErbB-1 抗体
  • ERBB1 抗体
  • Erbb2 抗体
  • Errb1 抗体
  • Errp 抗体
  • flb 抗体
  • HD-33 抗体
  • HER1 抗体
  • l(2)05351 抗体
  • l(2)09261 抗体
  • l(2)57DEFa 抗体
  • l(2)57Ea 抗体
  • l(2)57EFa 抗体
  • mENA 抗体
  • mor1 抗体
  • PIG61 抗体
  • top 抗体
  • top/DER 抗体
  • top/flb 抗体
  • Torpedo/DER 抗体
  • torpedo/egfr 抗体
  • wa-2 抗体
  • wa2 抗体
  • Wa5 抗体

Protein level used designations for EGFR

CG10079-PA , CG10079-PB , DER-Ellipse , EGF-receptor , EGFR , Egf receptor , Egfr-PA , Egfr-PB , drosophila epidermal growth factor receptor homologue , ellipse , ellipse torpedo , epidermal growth factor receptor , faint little ball , morphological defects 1 , torpedo , torpedo/DER , erbb1a , avian erythroblastic leukemia viral (v-erb-b) oncogene homolog , cell growth inhibiting protein 40 , cell proliferation-inducing protein 61 , proto-oncogene c-ErbB-1 , receptor tyrosine-protein kinase erbB-1 , EGFR-related peptide , Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) , avian erythroblastic leukemia viral (v-erbB) oncogene homolog , epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) , waved 2 , CER , epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) , egf receptor , receptor tyrosine kinase ErbB1

GENE ID SPECIES
100067755 Equus caballus
37455 Drosophila melanogaster
378478 Danio rerio
778955 Ciona intestinalis
5564544 Aedes aegypti
1956 Homo sapiens
24329 Rattus norvegicus
13649 Mus musculus
396494 Gallus gallus
397070 Sus scrofa
404306 Canis lupus familiaris
407217 Bos taurus
100008806 Oryctolagus cuniculus
100725363 Cavia porcellus
780479 Ovis aries
613027 Macaca mulatta
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