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anti-EGFR (EGFR) 抗体产品概述

Full name:
anti-Epidermal Growth Factor Receptor 抗体 (EGFR)
在www.antibodies-online.cn可供2266 Epidermal Growth Factor Receptor (EGFR) 抗体的42不同的供货商。 再加上,我们可以发EGFR 试剂盒 (127)EGFR 蛋白 (113)和数多这个蛋白质的别的产品。 总共2578 EGFR产品已列进来了。
别名:
9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, dEgfr, dEGFR1, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, Egf-r, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, top, top/DER, top/flb, Torpedo/DER, torpedo/egfr, wa-2, wa2, Wa5

所有可销售的anti-EGFR 抗体

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引用最多的anti-EGFR 抗体

  1. Human Polyclonal EGFR Primary Antibody for EIA - ABIN358328 : Aifa, Aydin, Nordvall, Lundström, Svensson, Hermanson: A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. in Experimental cell research 2004 (PubMed)
    Show all 5 references for ABIN358328

  2. Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN389891 : Kuribayashi, Kataoka, Kurabayashi, Miura: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. in Endocrinology 2004 (PubMed)
    Show all 3 references for ABIN389891

  3. Human Polyclonal EGFR Primary Antibody for WB - ABIN391933 : Kapoor, Zhan, Johnson, ORourke: Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for ABIN391933

  4. Human Polyclonal EGFR Primary Antibody for ELISA, WB - ABIN1532008 : Ullrich, Coussens, Hayflick, Dull, Gray, Tam, Lee, Yarden, Libermann, Schlessinger: Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. in Nature 1984 (PubMed)

  5. Dog (Canine) Monoclonal EGFR Primary Antibody for EIA, IF - ABIN126767 : Kondo, Higa-Nakamine, Maeda, Toku, Kakinohana, Sugahara, Kukita, Yamamoto: Stimulation of Cell Migration by Flagellin Through the p38 MAP Kinase Pathway in Cultured Intestinal Epithelial Cells. in Journal of cellular biochemistry 2015 (PubMed)

  6. Human Polyclonal EGFR Primary Antibody for FACS, IHC (p) - ABIN651628 : Lowenstein, Daly, Batzer, Li, Margolis, Lammers, Ullrich, Skolnik, Bar-Sagi, Schlessinger: The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. in Cell 1992 (PubMed)

  7. Human Monoclonal EGFR Primary Antibody for FACS, IF - ABIN452102 : Wikstrand, Hale, Batra, Hill, Humphrey, Kurpad, McLendon, Moscatello, Pegram, Reist: Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. in Cancer research 1995 (PubMed)

  8. Human Monoclonal EGFR Primary Antibody for IHC (p) - ABIN1687358 : Krager, Sarkar, Twait, Lill, Koland: A novel biotinylated lipid raft reporter for electron microscopic imaging of plasma membrane microdomains. in Journal of lipid research 2012 (PubMed)

更多抗EGFR的相互作用对抗体

Horse (Equine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Results indicated that most periocular squamous cell carcinomas of horses expressed epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2 (显示 ERBB2 抗体)).

Fruit Fly (Drosophila melanogaster) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Loss of Usp5 (显示 USP5 抗体) results in upregulation of Notch (显示 NOTCH1 抗体) signaling and downregulation of RTK signaling by EGF receptor (EGFR) and Sevenless (Sev), leading to impaired photoreceptor development.

  2. These data demonstrate a strong genetic link between dG9a and the EGFR signaling pathway.

  3. Avermectin directly interacts with EGFR and leads to the activation of the EGFR/AKT (显示 AKT1 抗体)/ERK (显示 MAPK1 抗体) pathway.

  4. The dorsoventral patterning and EGFR signaling genes play essential roles in correct identity determination and differentiation of lateral glia in the Drosophila nervous system.

  5. Data suggest that OSCP1 (organic solute carrier partner 1 (显示 OSCP1 抗体)) plays multiple roles during eye development in D. melanogaster; OSCP1 (显示 OSCP1 抗体) regulates developmental gene expression and epidermal growth factor receptor signaling pathway in imaginal discs of eye.

  6. The vector of cell movement is regulated by localised epidermal growth factor (EGF (显示 EGF 抗体)) signalling from the distally placed tip cell lineage and the acquisition of planar polarity leads to asymmetric pulsatile Myosin II accumulation.

  7. Our findings provide in vivo evidence for the role of adult neurons in the maintenance of glia and a novel role for EGFR signaling in the autophagic flux.

  8. Gro (显示 CXCL1 抗体) inhibits rho expression in undifferentiated cells and represses the expression of both ato and rho in non-R8 precursors during initiation of photoreceptor differentiation in an E(spl (显示 SGPL1 抗体))-dependent manner.

  9. strategy for producing ordered square cell packing configurations in epithelia and reveal a molecular mechanism by which organized tissue structure is generated through spatiotemporally regulated responses to EGF receptor activation.

  10. the findings indicate that Vps4 (显示 VPS4A 抗体) can promote EGFR activity through an endocytosis-independent mechanism.

Zebrafish Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Study demonstrated that IGF-I (显示 IGF1 抗体) can stimulate egfr expression in both follicles cell culture and intact follicles promoting oocyte maturation.

  2. These results indicate that maintenance of Pgrmc1 (显示 PGRMC1 抗体) signaling is required for Egfr expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr in maintaining meiotic arrest through estrogen activation of Gper (显示 GPER 抗体).

  3. EGFR signaling in vertebrate oocytes can prevent meiotic progression.

  4. the expression of EGFR was mainly restricted to the follicle cells with little expression in the oocytes

Human Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. EGF (显示 EGF 抗体), HB-EGF (显示 HBEGF 抗体), TGF-alpha (显示 TGFA 抗体) and beta-Cellulin mediate EGFR nuclear translocation.

  2. Results from circular dichroism spectroscopy, size exclusion chromatography with multiangle light scattering, dynamic light scattering, analytical ultracentrifugation, and small angle X-ray scattering each provide evidence that the EGFR and HER3 (显示 ERBB3 抗体) C-terminal tails are intrinsically disordered with extended, non-globular structure in solution.

  3. EGF (显示 EGF 抗体) stimulation specifically increases the transport efficiency of newly synthesized EGFRs from the endoplasmic reticulum to the plasma membrane.

  4. The conformation of the EGFR transmembrane domain dimer dynamically adapts to the local membrane environment.

  5. hypoxic tumour microenvironment may have a major role in mediating resistance against anti-EGFR strategies by downregulating EGFR molecules on tumour cells

  6. Molecular dynamics simulations of WT and mutant EGFR suggest a model in which M766T activates the kinase domain by disrupting conserved autoinhibitory interactions between M766 and hydrophobic residues in the activation segment.

  7. LPA1 (显示 LPAR1 抗体) plays a critical role in EGF (显示 EGF 抗体) responses and that FFA4 agonists inhibit proliferation by suppressing positive cross-talk between LPA1 (显示 LPAR1 抗体) and the EGF receptor

  8. EGFR p.T790M mutation is associated with tumor progression.

  9. We retrospectively reviewed 183 Japanese patients with epidermal growth factor receptor (EGFR)-tyrosine kinase (显示 TXK 抗体) inhibitor-naive non-small cell lung cancer harboring EGFR mutations

  10. Biochemical and in vitro interaction studies suggest direct interference with the assembly of the wild-type ErbB-2 (显示 ERBB2 抗体)-ErbB-3 (显示 ERBB3 抗体) heterodimer as the underlying mode of action. To the best of our knowledge, this is the first agent to target the TMDs of ErbB to delay tumor growth and signaling

Mouse (Murine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. These data highlight the importance of EGFR signaling and its downstream signaling cascade in postnatal beta cell growth.

  2. aldosterone induced the phosphorylation of EGFR through generation of reactive oxygen species.

  3. IL-4 (显示 IL4 抗体)-stimulated HB-EGF (显示 HBEGF 抗体)-dependent transactivation of EGFR in macrophages may mediate inhibitory feedback for M2 polarization and HB-EGF (显示 HBEGF 抗体) production, thereby inhibiting gastrointestinal tumor growth.

  4. Inhibition of EGFR reduces p38 MAPK (显示 MAPK14 抗体), resulting in decreased expression of hypoxia-inducible factor-1alpha, metalloproteinase 1, and VEGF (显示 VEGFA 抗体), leading to suppressions of angiogenesis and tumorigenesis.

  5. Data show that oligodendrocyte transcription factor 2 (Olig2 (显示 OLIG2 抗体)) deletion causes platelet-derived growth factor receptor (PDGFR (显示 PDGFRB 抗体)) downregulation and reciprocal epidermal growth factor receptor (EGFR) upregulation.

  6. EGFR and Nestin (显示 NES 抗体) showed to have vital role during mice development, and considered to be suitable markers for the study of skin stem cells.

  7. EGFR suppression of mitotic regulators including Rcc2 (显示 RCC2 抗体) and Stathmin 1 (显示 STMN1 抗体) are a mechanism for catagen induction in mouse skin

  8. Ambient fine particulate matter-induced myocarditis is mediated by EGFR/Akt (显示 AKT1 抗体) signaling and overexpression of NLRP3 (显示 NLRP3 抗体) and NLRP12 (显示 NLRP12 抗体).

  9. These data suggest that vandetanib could suppress the progression of tumors harboring an activating EGFR mutation.

  10. These findings suggest that maintaining ADAM17 (显示 ADAM17 抗体)-EGFR epithelial signaling is necessary for the recovery from UC and would be beneficial to therapeutic strategies targeting ADAM17 (显示 ADAM17 抗体)-mediated TNF-a (显示 TNF 抗体) shedding.

Pig (Porcine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Syndecan-4 (显示 SDC4 抗体) mediates porcine respiratory and reproductive syndrome virus entry by interacting with EGFR.

  2. These results indicate that cAMP and oocyte-secreted factors cooperate to promote EGF receptor functionality in developing cumulus oocyte complexes, representing a key component of the acquisition of oocyte developmental competence.

  3. patients experiencing gefitinib dose reduction or short-term treatment interruption due to toxicities did not show inferior survival, compared to those receiving full dose of gefitinib in non-small cell lung cancer patients with EGFR mutation

  4. Report EGFR expression in the normal pancreas.

  5. Injury and activation of purinergic receptors and direct activation of EGFR via EGF (显示 EGF 抗体) induce distinct downstream pathways.

  6. Data suggest that the mechanism of hypoxia-induced increased activation of EGFR kinase is mediated by nNOS (显示 NOS1 抗体)-derived nitric oxide.

  7. EGFR, VEGFR (显示 KDR 抗体) and FGFR (显示 FGFR2 抗体) are expressed in porcine oviduct and endometrium during the time of implantation [review]

  8. the restricted presence of the functional full-size receptor to the epithelial layer indicates a specific role during early embryonic development, whereas truncated EGF-R forms may potentially regulate contractions and blood flow in the oviduct

  9. The phase-related expression of EGF (显示 EGF 抗体) and EGFR in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF (显示 EGF 抗体) and its receptor on the uterine artery and the region supplying these vessels.

  10. This result suggests that ubiquitination of the kinase-impaired receptor can mediate its internalization by the clathrin pathway.

Cow (Bovine) Epidermal Growth Factor Receptor (EGFR) interaction partners

  1. Stimulation of bovine oviduct epithelial cell EGFR with EGF (显示 EGF 抗体) (human recombinant EGF (显示 EGF 抗体)) alone or with EGF (显示 EGF 抗体) in postovulatory/follicular phases (not luteal phase) up-regulates phosphorylation of MAPKs; heat blocks effects of EGF (显示 EGF 抗体) on phosphorylation of MAPKs.

  2. Expression of the erbB/HER receptor family in the bovine uterus during the sexual cycle and the relation of this family to serum sex steroids.

  3. Regulation of the sperm EGFR by ouabain leads to initiation of the acrosome reaction.

  4. EGFR may simultaneously activate c-Src (显示 SRC 抗体) and PI3K to amplify the oxytocin signaling to increase the output of PGF (显示 PGF 抗体)(2 alpha) in endometrial epithelial cells.

  5. results indicate that arginase induction depends in part on epidermal growth factor (EGF (显示 EGF 抗体)) receptor activity, and that EGFR inhibitors may attenuate vascular remodeling without affecting nitric oxide release

  6. Data suggest that epidermal growth factor (EGF (显示 EGF 抗体)) and EGF (显示 EGF 抗体) receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.

  7. MT1-MMP (显示 MMP14 抗体) has a role in signaling events mediating EGFR transactivation

  8. possible cooperative role of the EGF (显示 EGF 抗体) and HGF (显示 HGF 抗体) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

  9. EGFR is stimulated during capacitation via PKA activation. More activation induces the acrosome reaction, which is induced by GPCR via EGFR transactivation by a signaling pathway involving PKA, SRC & metalloproteinase & effectors PI3K, PLC & PKC.

EGFR 抗原简介

Antigen Summary

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with EGFR

  • epidermal growth factor receptor (EGFR) 抗体
  • Epidermal growth factor receptor (Egfr) 抗体
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) 抗体
  • epidermal growth factor receptor (egfr1) 抗体
  • epidermal growth factor receptor (AaeL_AAEL004319) 抗体
  • epidermal growth factor receptor (Egfr) 抗体
  • epidermal growth factor receptor (LOC100008806) 抗体
  • 9030024J15Rik 抗体
  • AI552599 抗体
  • C-erb 抗体
  • c-erbB 抗体
  • CG10079 抗体
  • D-Egf 抗体
  • d-egf-r 抗体
  • D-EGFR 抗体
  • dEgfr 抗体
  • dEGFR1 抗体
  • der 抗体
  • DER/EGFR 抗体
  • DER/faint little ball 抗体
  • DER/top 抗体
  • DER/torpedo 抗体
  • DER1 抗体
  • DER flb 抗体
  • Dmel\\CG10079 抗体
  • DmHD-33 抗体
  • EFG-R 抗体
  • Egf 抗体
  • Egf-r 抗体
  • egfr 抗体
  • egfr1 抗体
  • EGFR12 抗体
  • EGFR15 抗体
  • EK2-6 抗体
  • El 抗体
  • Elp 抗体
  • Elp-1 抗体
  • Elp-B1 抗体
  • Elp-B1RB1 抗体
  • Erbb 抗体
  • ErbB-1 抗体
  • ERBB1 抗体
  • Erbb2 抗体
  • Errb1 抗体
  • Errp 抗体
  • flb 抗体
  • HD-33 抗体
  • HER1 抗体
  • l(2)05351 抗体
  • l(2)09261 抗体
  • l(2)57DEFa 抗体
  • l(2)57Ea 抗体
  • l(2)57EFa 抗体
  • mENA 抗体
  • mor1 抗体
  • PIG61 抗体
  • top 抗体
  • top/DER 抗体
  • top/flb 抗体
  • Torpedo/DER 抗体
  • torpedo/egfr 抗体
  • wa-2 抗体
  • wa2 抗体
  • Wa5 抗体

Protein level used designations for EGFR

CG10079-PA , CG10079-PB , DER-Ellipse , EGF-receptor , EGFR , Egf receptor , Egfr-PA , Egfr-PB , drosophila epidermal growth factor receptor homologue , ellipse , ellipse torpedo , epidermal growth factor receptor , faint little ball , morphological defects 1 , torpedo , torpedo/DER , erbb1a , avian erythroblastic leukemia viral (v-erb-b) oncogene homolog , cell growth inhibiting protein 40 , cell proliferation-inducing protein 61 , proto-oncogene c-ErbB-1 , receptor tyrosine-protein kinase erbB-1 , EGFR-related peptide , Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) , avian erythroblastic leukemia viral (v-erbB) oncogene homolog , epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) , waved 2 , CER , epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) , egf receptor , receptor tyrosine kinase ErbB1

GENE ID SPECIES
100067755 Equus caballus
37455 Drosophila melanogaster
378478 Danio rerio
778955 Ciona intestinalis
5564544 Aedes aegypti
1956 Homo sapiens
24329 Rattus norvegicus
13649 Mus musculus
396494 Gallus gallus
397070 Sus scrofa
404306 Canis lupus familiaris
407217 Bos taurus
100008806 Oryctolagus cuniculus
100725363 Cavia porcellus
780479 Ovis aries
613027 Macaca mulatta
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