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anti-AFT1 (AFT1) 抗体产品概述

Full name:
anti-Activating Transcription Factor 1 抗体 (AFT1)
在www.antibodies-online.cn可供148 Activating Transcription Factor 1 (AFT1) 抗体的27不同的供货商。 再加上,我们可以发AFT1 试剂盒 (28)AFT1 蛋白 (14)和数多这个蛋白质的别的产品。 总共204 AFT1产品已列进来了。
别名:
Atf-1, ATF1, EWS-ATF1, FUS/ATF-1, TREB36, wu:fc92c07, zgc:64099

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引用最多的anti-AFT1 抗体

  1. Human Polyclonal AFT1 Primary Antibody for FACS, WB - ABIN651055 : Vega, Salas, Milne, Carracedo, Ribas, Ruibal, de León, González-Hernández, Benítez, Carracedo: Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. in Gynecologic oncology 2008 (PubMed)
    Show all 2 references for ABIN651055

  2. Cow (Bovine) Polyclonal AFT1 Primary Antibody for IHC, WB - ABIN2780654 : Iwasaki, Hailemariam, Tsuji: PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element. in The Journal of biological chemistry 2007 (PubMed)

  3. Cow (Bovine) Polyclonal AFT1 Primary Antibody for WB - ABIN2780653 : Somers, Viero, Nathan, Teshima, Pereira, Zielenska: Association of the t(12;22)(q13;q12) EWS/ATF1 rearrangement with polyphenotypic round cell sarcoma of bone: a case report. in The American journal of surgical pathology 2005 (PubMed)

更多抗AFT1的相互作用对抗体

Human Activating Transcription Factor 1 (AFT1) interaction partners

  1. our results demonstrated that miR (显示 MLXIP 抗体)-30a may modulate the radiosensitivity of non-small cell lung cancer (NSCLC) through reducing the function of ATF1 in phosphorylation of ATM (显示 ATM 抗体) and have potential therapeutic value.

  2. genetic association studies in a population in China: Data suggest that an SNP in ATF1 (rs11169571) is associated with essential hypertension in the population studied; altered binding of microRNA-1283 appears to be involved.

  3. EWSR1 (显示 EWSR1 抗体)-ATF1 fusion gene was found in hyalinizing clear cell carcinoma

  4. Heme activates the ATF1 pathway in human macrophages via AMPK (显示 PRKAA1 抗体), and that a similar response occurs after treatment of cells with metformin.

  5. ATF1 protein expression was significantly lower in colorectal cancer tissues than corresponding normal tissues; patients with higher ATF1 expression levels have a significantly higher survival rate than those with lower expression

  6. Review: discuss clinicopathologic and molecular features of group of neoplasms unified by the presence of EWSR1 (显示 EWSR1 抗体)-CREB1 (显示 CREB1 抗体) and EWSR1 (显示 EWSR1 抗体)-ATF1 genetic fusions.

  7. ATF-1 mediates HO-1 (显示 HMOX1 抗体) induction by heme and drives macrophage adaptation to intraplaque hemorrhage.

  8. Hyalinizing clear-cell carcinoma is a unique low-grade salivary carcinoma that consistently harbors EWSR1 (显示 EWSR1 抗体)-ATF1 fusion.

  9. Differential expression of CREB (显示 CREB1 抗体)/ATF transcription factors could be observed on neurogenic induction, pointing to a decisive role of the cAMP-CREB (显示 CREB1 抗体)/ATF system.

  10. An increase in phosphorylation of CREB (显示 CREB1 抗体)/ATF-1 in human dental pulp cells was noted after exposure to PGF2alpha for 1-20 min,with a maximal induction at 10 min.

Mouse (Murine) Activating Transcription Factor 1 (AFT1) interaction partners

  1. the HSF1 (显示 HSF1 抗体) complex, including BRG1 (显示 SMARCA4 抗体) and lysine acetyltransferases p300 (显示 NOTCH1 抗体) and CREB-binding protein (CBP (显示 CREBBP 抗体)), is formed in a manner dependent on the phosphorylation of ATF1

  2. conclude that HO-1 (显示 HMOX1 抗体) regulates DC maturation and function by modulating the p38 MAPK (显示 MAPK14 抗体)-CREB (显示 CREB1 抗体)/ATF1 signaling axis

  3. Dehydroepiandrosterone sulfate (DHEAS (显示 SULT2A1 抗体))-induced signaling is mediated through interaction with a membrane-bound G-protein-coupled receptor (显示 GPR34 抗体), since silencing of Gnalpha11 leads to the abolition of the DHEAS (显示 SULT2A1 抗体)-induced stimulation of Erk1/2 (显示 MAPK1/3 抗体), ATF-1, and CREB (显示 CREB1 抗体).

  4. indicate that dysregulation of p38 MAPK (显示 MAPK14 抗体)-CREB (显示 CREB1 抗体)/ATF1 signaling axis underlies the altered function and phenotype in Nrf2 (显示 NFE2L2 抗体)-deficient DCs

  5. Forced expression of EWS/ATF1 resulted in the development of EWS/ATF1-dependent sarcomas. Lineage-tracing experiments indicated that neural crest-derived cells were subject to EWS/ATF1-driven transformation.

  6. miR (显示 MLXIP 抗体)-34c functions, at least partially, by targeting the ATF1 gene in germ cell apoptosis, providing a novel mechanism with involvement of miRNA in the regulation of germ cell apoptosis.

  7. ATF1 is a novel substrate of RSK2 (显示 RPS6KA3 抗体) and that RSK2 (显示 RPS6KA3 抗体)-ATF1 signaling plays an important role in EGF (显示 EGF 抗体)-induced neoplastic cell transformation.

  8. study demonstrates a role for trophic signaling and constitutive activation of activating transcription factor 1(Atf1) and cAMP response element-binding protein (CREB) at the time of zygotic genome activation

  9. MSK1 (显示 RPS6KA5 抗体) and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB (显示 CREB1 抗体) and ATF1 in fibroblasts.

  10. phosphorylation by the ERK MAPK (显示 MAPK1 抗体) pathway is required for epidermal growth factor (显示 EGF 抗体)-induced c-jun (显示 JUN 抗体) expression

Rabbit Activating Transcription Factor 1 (AFT1) interaction partners

  1. Data indicate increasing expression for CREB (显示 CREB1 抗体), ATF1, and ATF3 (显示 ATF3 抗体) during gastrulation.

AFT1 抗原简介

Antigen Summary

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

Alternative names and synonyms associated with AFT1

  • activating transcription factor 1 (atf1) 抗体
  • activating transcription factor 1 (ATF1) 抗体
  • activating transcription factor 1 (MGC85066) 抗体
  • activating transcription factor 1 (Atf1) 抗体
  • activating transcription factor 1 (LOC100340999) 抗体
  • Atf-1 抗体
  • ATF1 抗体
  • EWS-ATF1 抗体
  • FUS/ATF-1 抗体
  • TREB36 抗体
  • wu:fc92c07 抗体
  • zgc:64099 抗体

Protein level used designations for AFT1

activating transcription factor 1 , cyclic AMP-dependent transcription factor ATF-1 , cAMP-dependent transcription factor ATF-1 , TCR-ATF1

GENE ID SPECIES
448303 Xenopus (Silurana) tropicalis
452429 Pan troglodytes
693644 Macaca mulatta
779184 Xenopus laevis
466 Homo sapiens
496344 Xenopus laevis
486545 Canis lupus familiaris
506967 Bos taurus
11908 Mus musculus
315305 Rattus norvegicus
325609 Danio rerio
100340999 Oryctolagus cuniculus
100719533 Cavia porcellus
426873 Gallus gallus
101117917 Ovis aries
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