anti-IGFBP3 (IGFBP3) 抗体产品概述

Full name:
anti-Insulin-Like Growth Factor Binding Protein 3 抗体 (IGFBP3)
在www.antibodies-online.cn可供232 Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) 抗体的28不同的供货商。 再加上,我们可以发IGFBP3 试剂盒 (113)IGFBP3 蛋白 (48)和数多这个蛋白质的别的产品。 总共403 IGFBP3产品已列进来了。
别名:
AI649005, BP-53, IBP3, IGF-BP3, IGFBP-3, igfbp3, IGgfbp3, zgc:91788
列出全部抗体 基因 基因ID UniProt
IGFBP3 3486 P17936
IGFBP3 16009  
IGFBP3 24484 P15473

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引用最多的anti-IGFBP3 抗体

  1. Human Monoclonal IGFBP3 Primary Antibody for IF, WB - ABIN968565 : Campbell, Durham, Hayes, Suwanichkul, Powell: Insulin-like growth factor-binding protein-3 binds fibrinogen and fibrin. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for 968565

  2. Human Polyclonal IGFBP3 Primary Antibody for EIA, IHC (p) - ABIN359861 : Muzumdar, Ma, Fishman, Yang, Atzmon, Vuguin, Einstein, Hwang, Cohen, Barzilai: Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action. in Diabetes 2006 (PubMed)
    Show all 2 references for 359861

  3. Human Polyclonal IGFBP3 Primary Antibody for EIA, IHC (p) - ABIN359863 : Novosyadlyy, Dargel, Scharf: Expression of insulin-like growth factor-I and insulin-like growth factor binding proteins during thioacetamide-induced liver cirrhosis in rats. in Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005 (PubMed)
    Show all 2 references for 359863

  4. Human Polyclonal IGFBP3 Primary Antibody for IHC (p), ELISA - ABIN3043859 : Pu, Zheng, Zhang, Xiao, Xu, Liu, Wang, Wen, Zhou, Wu: Higher expression of mRNA and protein of insulin-like growth factor binding protein-3 in old rat penile tissues: implications for erectile dysfunction. in The journal of sexual medicine 2011 (PubMed)
    Show all 2 references for 3043859

  5. Human Polyclonal IGFBP3 Primary Antibody for IHC (p), WB - ABIN3044421 : Pu, Wen, Liu, Zheng, Xiao, Xu, Wang, Li, Zhang: shRNA constructs targeting IGFBP-3 alleviate age related erectile dysfunction in the rat. in The Journal of urology 2014 (PubMed)
    Show all 2 references for 3044421

  6. Human Polyclonal IGFBP3 Primary Antibody for ELISA, WB - ABIN314305 : Lin, Manson, Lee, Cook, Buring, Zhang: Intakes of calcium and vitamin D and breast cancer risk in women. in Archives of internal medicine 2007 (PubMed)

  7. Human Polyclonal IGFBP3 Primary Antibody for IF (p), IHC (p) - ABIN686497 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)

更多抗IGFBP3的相互作用对抗体

Zebrafish Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. insulin-like growth factor binding protein 3 exerts its ligand-independent action by antagonizing bone morphogenetic protein 2 (显示 BMP4 抗体) in zebrafish embryos

  2. IGFBP-3 plays an important role in regulating pharyngeal cartilage and inner ear development and growth in zebrafish.

Human Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. Increased IGFBP3 level as associated with decreased risk of frailty in men.

  2. Report serum IGF1 (显示 IGF1 抗体)/IGFBP3 levels in relation to clinical/pathobiological features of squamous cell carcinomas of the head and neck.

  3. Functional IGFBP-3 was significantly lower in postmenopausal women than in premenopausal women, for both patients with rheumatoid arthritis and controls. There was a significant decrease in plasma functional IGFBP-3 levels in postmenopausal RA in comparison to healthy premenopausal subjects.

  4. study suggests high-order interactions of the IGFBP-3 rs2854744 AA genotype, BMI>/=24kg/m2, and DISI<9.85 mg/day on increased BC risk, particularly among postmenopausal women

  5. IGFBP2 (显示 IGFBP2 抗体) and IGFBP3 may serve as compensatory biomarkers for CA19-9. Early diagnosis with this marker combination may improve the prognosis of invasive ductal adenocarcinoma of pancreas patients.

  6. The stratification of individuals by gender revealed that Slovak males carrying IGFBP-3 G alleles (G32G or GG) had marginally increased risk for developing MDD as compared to CC homozygous males (p=0.09). In women, inverse association was observed between SNP rs1042522 and MDD risk (p=0.04 for recessive model).

  7. this study identified several loci associated with circulating IGF-I (显示 IGF1 抗体) and IGFBP-3 concentrations and provides clues to the potential role of the IGF axis in mediating effects of known (FOXO3 (显示 FOXO3 抗体)) and novel (ASXL2 (显示 ASXL2 抗体)) longevity-associated loci.

  8. these findings suggest that IGFBP-3 suppresses transcription of EGR1 (显示 EGR1 抗体) and its target genes bFGF (显示 FGF2 抗体) and PDGF (显示 PDGFA 抗体) through inhibiting IGF-1 (显示 IGF1 抗体)-dependent ERK (显示 EPHB2 抗体) and AKT (显示 AKT1 抗体) activation.

  9. results indicate that hypoxia suppresses the osteogenic differentiation of mesenchymal stem cells via IGFBP3 up-regulation.

  10. Data suggest that serum levels IGF-I (insulin-like growth factor I (显示 IGF1 抗体)) and IGFBP-3 (insulin-like growth factor binding protein 3) in pediatric patients with osteogenesis imperfecta (显示 COL1A2 抗体) (OI) and short statue are not different according to severity of OI or type of OI (patients with types 3 and 4 were investigated here); all patients had been treated with intravenous neridronate every 3 months for at least 2 years.

Mouse (Murine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. The study shows that the anti-tumoral effect of IGFBP-3 is due to inhibition of the Wnt (显示 WNT2 抗体) pathway and depends upon the presence of CD44 (显示 CD44 抗体), a receptor protein known to modulate Wnt (显示 WNT2 抗体) signaling.

  2. IGFBP-3 influences severity of DSS (显示 PMP22 抗体)-induced colitis.

  3. our studies found that the deletion of IGFBP3 results in behavioral impairments that are associated with abnormal synaptic function and monoaminergic neurotransmission, which helps to characterize the critical role of IGFBP3 in the brain

  4. IGFBP-3 is an aggravating factor during hepatic ischemia-repefusion injury.

  5. An increase in IGFBP-3 post-trauma may play an important role in limiting trauma-induced inflammatory and apoptotic pathways leading to retinal damage.

  6. Even though knockout of IGFBP-3 is associated with only a subtle phenotype under control conditions, our results reveal that loss of this gene has measurable effects on breast carcinogenesis and breast cancer metastasis.

  7. Igfbp3 is a marker for culture-activated hepatic stellate cells and plays a role in HSC (显示 FUT1 抗体) migration.

  8. Igfbp2 (显示 IGFBP2 抗体)-5 are expressed in distinct and complementary patterns during cochlear development.

  9. IGFBP-3 has novel protective effects on retinal and systemic vasculature and may be a therapeutic candidate for ocular complications such as diabetic retinopathy.

  10. IGFBP-3 activates inhibitory Smad (显示 SMAD1 抗体) signaling in 3T3-L1 cells and that endogenous IGFBP-3 modulates their adipogenic differentiation by regulating cell sensitivity towards the inhibitory effect of TGFbeta (显示 TGFB1 抗体).

Cow (Bovine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. These data suggest that endogenous IGFBP-3 plays a role in intrinsic apoptosis by facilitating phosphorylation and nuclear export of Nur77 (显示 NR4A1 抗体) to the cytoplasm where it exerts its apoptotic effect.

  2. The present study suggests that the insulin (显示 INS 抗体) like growth factor (IGF) system or imbalances between IGF and IGF binding (显示 HTRA1 抗体) proteins may be involved in cystic ovary disease of cattle.

  3. spatial and temporal patterns of expression of IGFBP-2 (显示 IGFBP2 抗体) and -3 were markedly altered in the placentomes of nuclear transfer pregnancies

  4. stimulation of IGFBP-3 mRNA levels by mitogens is regulated through both the PI3K and MAPK (显示 MAPK1 抗体) pathways in bovine mammary epithelial cells

  5. Preincubation of erythroid cells with thrombospondin 1 (显示 THBS1 抗体) eliminated the inhibitory activity of IGFBP-3

  6. GH, IGF-I (显示 IGF1 抗体) and IGF-IBP3 regulated the growth and development traits in different growth period.

  7. delivery of insulin-like growth factor-1 (IGF-1 (显示 IGF1 抗体), delivered at concentrations of 0, 10, 50, and 100 ng/mL) affects the endogenous expression of IGF-1 (显示 IGF1 抗体), its receptor (IGF-1R (显示 IGF1R 抗体)), and a well known IGF-1 (显示 IGF1 抗体) binding protein (IGFBP-3) by articular chondrocytes

  8. Multivariable adjusted analyses did not reveal a statistically significant linear relationship between IGF1 (显示 IGF1 抗体) or IGFBP3 concentrations or their molar ratio and risk of myocardial infarction

  9. Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.

Pig (Porcine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. IGF-I (显示 IGF1 抗体), IGF-II, and IGFBP-3 mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. Increased oxidative stress from high glucose enhances IGFBP-3 expression, inducing apoptosis

  3. Even though LRP-1 (显示 LRP1 抗体) mRNA and protein levels were dramatically reduced in LRP-1 (显示 LRP1 抗体)-silenced L6 cells compared with mock-silenced controls, rpIGFPB-3 suppressed proliferation rate to the same extent in both LRP-1 (显示 LRP1 抗体)-silenced and mock-silenced cultures.

  4. cloning and sequencing; regulation of IGFBP-3 transcription by FSH (显示 BRD2 抗体) suggests a role for IGFBP-3 in follicular development that may be independent of IGF-I (显示 IGF1 抗体)

  5. Follicle-stimulating hormone stimulation of IGFBP-3 transcription is mediated by cAMP via the PKA pathway and requires the P1-3 kinase and likely the MAPK (显示 MAPK1 抗体) pathways.

  6. TAF4b may thus be the TFIID (显示 TBP 抗体) component that binds to the TBP (显示 TBP 抗体) site on the IGFBP-3 promoter and is essential for FSH (显示 BRD2 抗体) induction of IGFBP-3.

  7. The results suggest that the expression of IGF2 and IGFBP3 mRNA in the adipose tissue of pigs exhibits specific developmental changes and different patterns between the two pig breeds.

  8. allelic frequency of TAT (显示 C6orf134 抗体) in Chinese breeds was over 50%; allelic frequency of GGC (显示 GGCT 抗体) was over 50% in all European breeds. TAT/TAT (显示 C6orf134 抗体) pigs scored higher in meat color than GGC/GGC (显示 GGCT 抗体) pigs. results implied that IGFBP-3 may affect meat quality & carcass traits.

Horse (Equine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. Data suggest that metabolism of IGFBP3, IGF1 (insulin-like growth factor I), and IGF2 (insulin-like growth factor II) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).

IGFBP3 抗原简介

Antigen Summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with IGFBP3

  • insulin-like growth factor binding protein 3 (igfbp3) 抗体
  • insulin-like growth factor binding protein 3 (IGFBP-3) 抗体
  • insulin-like growth factor binding protein 3 (IGFBP3) 抗体
  • insulin-like growth factor binding protein 3 (LOC100220315) 抗体
  • insulin-like growth factor binding protein 3 (LOC100305016) 抗体
  • insulin-like growth factor binding protein 3 (Igfbp3) 抗体
  • insulin-like growth factor binding protein-3 (IGFBP-3) 抗体
  • AI649005 抗体
  • BP-53 抗体
  • IBP3 抗体
  • IGF-BP3 抗体
  • IGFBP-3 抗体
  • igfbp3 抗体
  • IGgfbp3 抗体
  • zgc:91788 抗体

Protein level used designations for IGFBP3

insulin-like growth factor-binding protein 3 , insulin-like growth factor binding protein 3 , IBP-3 , IGF-binding protein 3 , IGFBP-3 , acid stable subunit of the 140 K IGF complex , binding protein 29 , binding protein 53 , growth hormone-dependent binding protein , insulin-like growth factor binding protein-3 , insulin-like growth factor-binding protein (IGF-BP3)

GENE ID SPECIES
403079 Danio rerio
443497 Ovis aries
463396 Pan troglodytes
696868 Macaca mulatta
100136304 Oncorhynchus mykiss
100173070 Pongo abelii
100220315 Taeniopygia guttata
100305016 Ictalurus punctatus
3486 Homo sapiens
491618 Canis lupus familiaris
16009 Mus musculus
282261 Bos taurus
24484 Rattus norvegicus
420790 Gallus gallus
448812 Sus scrofa
100714097 Cavia porcellus
100286737 Ovis aries
100034155 Equus caballus
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