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anti-RPS6KA3 (RPS6KA3) 抗体产品概述

Full name:
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 抗体 (RPS6KA3)
在www.antibodies-online.cn可供149 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) 抗体的18不同的供货商。 再加上,我们可以发RPS6KA3 蛋白 (13)RPS6KA3 试剂盒 (1)和数多这个蛋白质的别的产品。 总共174 RPS6KA3产品已列进来了。
别名:
CLS, HU-3, ISPK-1, MAPKAPK1B, MPK-9, MRX19, p90-RSK2, pp90RSK2, RSK, RSK2, S6K-alpha3
列出全部抗体 基因 基因ID UniProt
RPS6KA3 110651 P18654
RPS6KA3 6197 P51812
RPS6KA3    

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引用最多的anti-RPS6KA3 抗体

  1. Human Polyclonal RPS6KA3 Primary Antibody for EIA - ABIN358394 : Yang, Matsuda, Bialek, Jacquot, Masuoka, Schinke, Li, Brancorsini, Sassone-Corsi, Townes, Hanauer, Karsenty: ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. in Cell 2004 (PubMed)
    Show all 5 references for ABIN358394

  2. Human Polyclonal RPS6KA3 Primary Antibody for EIA, WB - ABIN360345 : Guimiot, Delezoide, Hanauer, Simonneau: Expression of the RSK2 gene during early human development. in Gene expression patterns : GEP 2003 (PubMed)
    Show all 5 references for ABIN360345

  3. Human Monoclonal RPS6KA3 Primary Antibody for ICC, FACS - ABIN969386 : Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. in Molecular cell 2009 (PubMed)
    Show all 2 references for ABIN969386

  4. Cow (Bovine) Polyclonal RPS6KA3 Primary Antibody for WB - ABIN372713 : Sheffler, Kroeze, Garcia, Deutch, Hufeisen, Leahy, Brüning, Roth: p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 2 references for ABIN372713

  5. Human Monoclonal RPS6KA3 Primary Antibody for EIA, IF - ABIN1108903 : Koutsilieris, Mitsiades, Bogdanos, Dimopoulos, Karamanolakis, Milathianakis, Tsintavis: Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D3 prostate cancer patients with bone metastases. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)

更多抗RPS6KA3的相互作用对抗体

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. The purified protein can be fully activated in vitro by phosphorylation with protein kinases ERK2 (显示 MAPK1 抗体) and PDK1 (显示 PDPK1 抗体).

  2. Downregulation of Rps6ka3 is a promising strategy for the treatment of multiple sclerosis.

  3. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (显示 PDPK1 抗体))-p90 (显示 GPAM 抗体) kDa ribosomal S6 kinases (Rsks) Rsk1 (显示 RPS6KA1 抗体)/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  4. RSK2 regulates craniofacial development including tooth development and patterning via novel transcriptional targets

  5. The results of this study show that RSK2 loss-of-function is associated in the dentate gyrus with multi-level alterations that encompass modifications of glutamate (显示 GRIN1 抗体) receptor channel properties, synaptic transmission.

  6. We propose that loss of function mutations in RSK2 that lead to Coffin-Lowry syndrome are related to defects in neuronal growth due to impaired RSK2-dependent PLD1 activity resulting in a reduced vesicle fusion rate and membrane supply.

  7. RSK2 interacted and phosphorylated GSK-3beta (显示 GSK3b 抗体) at Ser9. Notably, GSK-3beta (显示 GSK3b 抗体) phosphorylation at Ser9 was suppressed in RSK2(-/-) mouse embryonic fibroblasts.

  8. Pin1 (显示 PIN1 抗体) plays a critical role in tumorigenesis plausibly via physical interaction with RSK2 and reciprocal phosphorylation

  9. This study showed that RSK2 signaling contributes to morphine analgesia in the tail withdrawal response.

  10. Results show increased protein levels of Rsk1 (显示 RPS6KA1 抗体) and Rsk2 in the striatum of Huntington disease (显示 HTT 抗体) mice and and striatal cells transfected with full-length mutant Huntingtin (显示 HTT 抗体).

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. we discuss the function of the RSK2 signaling axis by interactions with binding partners in cancer development--{REVIEW}

  2. Results showed that RSK2 gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  3. Upregulated expression of RSK2 is associated with breast cancer.

  4. Data show that the 90 kDa ribosomal protein S6 (显示 RPS6 抗体) kinases RSK1 (显示 RPS6KA1 抗体) and RSK2 play a key role in the homing of ovarian cancer cells in metastatic sites by regulating cell adhesion and invasion.

  5. RSK1 (显示 RPS6KA1 抗体) and 3 but not RSK2 are down-regulated in breast tumour and are associated with disease progression. RSK (显示 RPS6KA1 抗体) may be a key component in the progression and metastasis of breast cancer.

  6. This case is one of the few examples where RPS6KA3 mutations are associated with a non-specific X-linked mental retardation.

  7. Results indicate that the phosphorylation of EphA2 (显示 EPHA2 抗体) at Ser (显示 SIGLEC1 抗体)-897 is controlled by RSK (显示 RPS6KA1 抗体) and the RSK (显示 RPS6KA1 抗体)-EphA2 (显示 EPHA2 抗体) axis might contribute to cell motility and promote tumour malignant progression.

  8. miR (显示 MLXIP 抗体)-191 represses proliferation in primary human fibroblasts via targeting multiple proto-oncogenes, including CDK9 (显示 CDK9 抗体), NOTCH2 (显示 NOTCH2 抗体), and RPS6KA3.

  9. This is the first report of exon skipping from an exonic mutation of RPS6KA3, demonstrating that a missense mutation and concomitant disruption of normal splicing contribute to the manifestation of CLS (显示 CLS 抗体)

  10. SL0101 and BI-D1870 induce distinct off-target effects in mTORC1-p70S6K (显示 RPS6KB1 抗体) signaling, and thus, the functions previously ascribed to RSK1 (显示 RPS6KA1 抗体)/2 based on these inhibitors should be reassessed.

RPS6KA3 抗原简介

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA3

  • ribosomal protein S6 kinase polypeptide 3 (Rps6ka3) 抗体
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) 抗体
  • CLS 抗体
  • HU-3 抗体
  • ISPK-1 抗体
  • MAPKAPK1B 抗体
  • MPK-9 抗体
  • MRX19 抗体
  • p90-RSK2 抗体
  • pp90RSK2 抗体
  • RSK 抗体
  • RSK2 抗体
  • S6K-alpha3 抗体

Protein level used designations for RPS6KA3

90 kDa ribosomal protein S6 kinase 3 , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , p90-RSK 3 , p90RSK3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase 2 , ribosomal protein S6 kinase alpha-3 , insulin-stimulated protein kinase 1

GENE ID SPECIES
110651 Mus musculus
6197 Homo sapiens
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