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抗Human MAPK6 抗体:
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抗Mouse (Murine) MAPK6 抗体:
Rat (Rattus) Monoclonal MAPK6 Primary Antibody for BI, IF - ABIN967749
Clark, Hynes: Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization. in The Journal of biological chemistry 1996
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Human Monoclonal MAPK6 Primary Antibody for FACS, ELISA - ABIN969115
Déléris, Rousseau, Coulombe, Rodier, Tanguay, Meloche: Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. in Journal of cellular physiology 2008
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Human Monoclonal MAPK6 Primary Antibody for FACS, ELISA - ABIN966092
Klinger, Turgeon, Lévesque, Wood, Aagaard-Tillery, Meloche: Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality. in Proceedings of the National Academy of Sciences of the United States of America 2009
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MPK6-mediated regulation of MYB15 plays an important role in cold stress signaling in Arabidopsis.
Data report that MPK3/MPK6 and their substrate ERF6 promote the biosynthesis of IGSs and the conversion of I3G to 4MI3G, a target of PEN2/PEN3-dependent chemical defenses in plant immunity.
Data show that the protein kinases MPK3 (显示 MAPK3 抗体) and MPK6 can both interact with SPOROCYTELESS/NOZZLE (SPL (显示 SGPL1 抗体)) in vitro and in vivo and can phosphorylate the SPL (显示 SGPL1 抗体) protein in vitro.
AIK1-MKK5 (显示 MAP2K5 抗体)-MPK6 cascade functions in the abscisic acid regulation of primary root growth and stomatal response.
A novel mechanism for PIN1 phosphorylation involving MKK7 (显示 MAP2K7 抗体) and MPK6 in shoot branching regulation in Arabidopsis.
MKK4 (显示 MAP2K4 抗体), MKK5 (显示 MAP2K5 抗体), MKK7 (显示 MAP2K7 抗体), and MKK9, are responsible for the activation of MPK3 (显示 MAPK3 抗体) and MPK6 by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (显示 MAPK1 抗体) signaling through MKK4 (显示 MAP2K4 抗体)/5/7/9-MPK3 (显示 MAPK3 抗体)/6 cascades.
Phosphatase AP2C1, as well as AP2C1-targeted MPK3 (显示 MAPK3 抗体) and MPK6, are important regulators of plant-nematode interaction, where the co-ordinated action of these signalling components ensures the timely activation of plant defence.
Mitogen-activated protein kinase 6 (MPK6) promoted C-terminal end of ORE3/EIN2 (CEND cleavage and nuclear translocation. Nuclear CEND accumulated ETHYLENE INSENSITIVE3 (EIN3), a transcription factor that accelerates MeJA-induced leaf senescence.
Results demonstrated the contribution of MPK3 (显示 MAPK3 抗体) and MPK6 to riboflavin-induced resistance.
MPK6 phosphorylates EB1c, but not EB1a, and has a role in maintaining regular planes of cell division under stress conditions.
There was significant association between p38gamma (显示 MAPK12 抗体) expression and esophageal squamous cell carcinoma clinical stage, lymph nodes metastases, and tumor volume. p38delta (显示 MAPK1/3 抗体) overexpression can promote tumorigenesis in nude mice model xenografted with Eca109 cells whose basal level of p38delta (显示 MAPK1/3 抗体) was stably over-expressed and p38gamma (显示 MAPK12 抗体) was stably knocked down.
Study revealed a post-translational regulation of TDP2 (显示 TDP2 抗体) activity and discovered a new role of ERK3 (显示 MAPK4 抗体) in increasing cancer cells' DNA damage response and chemoresistance to Top2 (显示 TOP2A 抗体) inhibitors.
This study reveals a novel pathway that directly links ErbB4 (显示 ERBB4 抗体) and p38gamma (显示 MAPK12 抗体) to the transcriptional machinery of NKx2.5 (显示 NKX2-5 抗体)-GATA4 (显示 GATA4 抗体) complex which is critical for cardiomyocyte formation during mammalian heart development.
during interphase ERK3 (显示 MAPK4 抗体) is mainly resident in the nucleoplasm in association with ribonuclear proteins involved in early pre-mRNA splicing, it undergoes cell cycle-dependent redistribution and, during apoptosis
Taken together our data suggest that as cells initiate adhesion to matrix increasing levels of ERK3 (显示 MAPK4 抗体) at the cell periphery are required to orchestrate cell morphology changes which can then drive migratory behavior.
p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD (显示 TSC2 抗体) therapy
MAPK6 could rescue the cell growth induced by miR499a and HBV
analysis of how allosteric regulation of p38gamma (显示 MAPK12 抗体) and PTPN3 (显示 PTPN3 抗体) involves a PDZ domain (显示 INADL 抗体)-modulated complex formation
ERK3 (显示 MAPK4 抗体) regulates endothelial cell migration, proliferation and tube formation by upregulating SRC-3 (显示 NCOA3 抗体)/SP-1 (显示 PSG1 抗体)-mediated VEGFR2 (显示 KDR 抗体) expression.
These findings further expand distinct roles of cyclin D3 (显示 CCND3 抗体) and suggest the potential activity of ERK3 (显示 MAPK4 抗体) in cell proliferation.
ERK3 (显示 RYK 抗体) biological activity is regulated by its cellular abundance through the control of protein stability
Data show that extracellular-regulated kinase 3 (ERK3 (显示 RYK 抗体)) specifically interacts with the MAPK-activated protein kinase 5 (MK5 (显示 MAPKAPK5 抗体) or PRAK (显示 MAPKAPK5 抗体)) in vitro and in vivo.
Results demonstrate a specific interaction between extracellular signal-regulated kinase 3 (ERK3) and mitogen-activated protein kinase-activated protein kinase-5 (MK5 (显示 MAPKAPK5 抗体)).
p38gamma (显示 MAPK12 抗体) MAP kinase (显示 MAPK1 抗体) (SAPK3/p38gamma (显示 MAPK12 抗体)) was shown to catalyse phosphorylation of SAP97 (显示 DLG1 抗体).
Results show that Cdo (显示 CDO1 抗体) is important for full Abl kinase activity, and Abl (显示 ABL1 抗体) is necessary for full activation of p38 MAPK (显示 MAPK14 抗体), during myogenic differentiation.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
, MAP kinase 6
, MAP kinase isoform p97
, MAPK 6
, extracellular signal-regulated kinase 3
, extracellular signal-regulated kinase, p97
, protein kinase, mitogen-activated 5
, protein kinase, mitogen-activated 6
, Erk-3 related
, mitogen activated protein kinase 4
, mitogen activated protein kinase 6
, protein kinase, mitogen activated kinase 4
, extracellular related kinase 3
, mitogen-activated protein kinase 6