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Rat (Rattus) BCL2 ELISA Kit for Sandwich ELISA - ABIN416111
Salama, Abdulla, AlRashdi, Ismail, Alkiyumi, Golbabapour: Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats. in BMC complementary and alternative medicine 2013
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Human BCL2 ELISA Kit for Sandwich ELISA - ABIN366834
Zhou, Zhao, Ma, Ju, Li, Li, Sun, Shi, Zhang, Lu: The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. in Biomaterials 2013
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Mouse (Murine) BCL2 ELISA Kit for Sandwich ELISA - ABIN415401
Nakano, Marui, Muranaka, Masumoto, Noma, Tabata, Ido, Tsubouchi, Ikeda, Sakata: Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin. in Interactive cardiovascular and thoracic surgery 2014
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Human BCL2 ELISA Kit for Sandwich ELISA - ABIN414423
Sasaki, Udaka, Tsunoda, Yamamoto, Tsuji, Oyamada, Oguchi, Mizutani: Analysis of p53 and miRNA expression after irradiation of glioblastoma cell lines. in Anticancer research 2012
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Cow (Bovine) BCL2 ELISA Kit for Sandwich ELISA - ABIN1118042
Mahmoud-Awny, Attia, Abd-Ellah, El-Abhar: Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-?, NF-?B and Nrf2/HO-1 Signaling Pathways. in PLoS ONE 2015
Rat (Rattus) BCL2 ELISA Kit for Sandwich ELISA - ABIN811440
Fang, Yang, Yang, Chen: Chitosan oligosaccharides attenuates oxidative-stress related retinal degeneration in rats. in PLoS ONE 2013
Th17 cells are resistant to glucocorticoid-induced apoptosis and cytokine suppression, at least in part due to high levels of BCL-2. These findings support a role of Th17 cells in glucocorticoid-resistant inflammatory conditions such as certain endotypes of asthma.
The findings are consistent with rs539846 influencing chronic lymphocytic leukemia (CLL) susceptibility through differential RELA (显示 NFkBP65 ELISA试剂盒) binding, with direct modulation of BMF (显示 BMF ELISA试剂盒) expression impacting on anti-apoptotic BCL2, a hallmark of oncogenic dependency in CLL.
DR_MOMP delivers a system-based biomarker with significant potential as a prognostic tool for stage III CRC (显示 CALR ELISA试剂盒) that significantly improves established histopathological risk factors. BCL-2-dependent signalling critically contributed to treatment responses in consensus molecular subtypes 1 and 3, linking for the first time specific molecular subtypes to apoptosis signalling.
Results show that expression level of mTOR (显示 FRAP1 ELISA试剂盒) and BCL2 are regulated by miR497 and provide evidence for their role in the development of TMZ-resistance phenotype of glioma cells.
Data show that MYC (显示 MYC ELISA试剂盒), BCL2 and BCL6 (显示 BCL6 ELISA试剂盒) translocation had no prognostic impact with respect to progression free survival (PFS) or overall survival (OS).
Interaction of the N-Terminal Tandem Domains of hnRNP (显示 HNRNPC ELISA试剂盒) LL with the BCL2 Promoter i-Motif DNA Sequence
MYC (显示 MYC ELISA试剂盒)/BCL2 co-expression is associated with a poorer prognosis and is independent of cell-of-origin classification in diffuse large B-cell lymphoma in the CNS.
These findings provide new insights into MCL-1 (显示 MCL1 ELISA试剂盒) ligands, and the interplay between DRP-1 (显示 CRMP1 ELISA试剂盒) and the anti-apoptotic BCL-2 family members in the regulation of apoptosis
Our findings suggest that the molecular machinery and mechanisms for executing Bcl-2-mediated apoptosis as observed in mammals are evolutionary ancient, with early regulation of apoptotic machineries closely resembling their modern counterparts in mammals rather than Caenorhabditis elegans or drosophila.
Clinical utility for selective inhibition of specific anti-apoptotic Bcl-2 family proteins has recently been realized with the Food and Drug Administration (FDA (显示 FDA ELISA试剂盒)) approval of venetoclax (formerly ABT-199/GDC (显示 SLC25A16 ELISA试剂盒)-0199) in relapsed chronic lymphocytic leukemia (CLL) with 17p deletion.
E2 protects skeletal myoblasts against apoptosis induced by H2 O2 modulating p53 (显示 TP53 ELISA试剂盒) and FoxO (显示 FOXO3 ELISA试剂盒) transcription factors and then their target genes Bcl-2, Bim (显示 BCL2L11 ELISA试剂盒), Puma (显示 BBC3 ELISA试剂盒), PERP, and MDM2 (显示 MDM2 ELISA试剂盒), without affecting Noxa (显示 PMAIP1 ELISA试剂盒) gene.
Bcl-2 expression has a significant impact on the mineralogical content of enamel crystals of tooth structure
The results suggest that CARP (显示 ANKRD1 ELISA试剂盒) can protect against hypoxia-reperfusion induced cardiomyocyte apoptosis, possibly through increasing anti-apoptosis Bcl2 gene expression.
This study provides evidence from transgenic mouse models that Crebbp (显示 CREBBP ELISA试剂盒) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.
an essential role for the binding of BCL2 to BIM (显示 BCL2L11 ELISA试剂盒) in the survival of noncycling NK cells.
LIGHT signalling pathway combined with IFN-gamma (显示 IFNG ELISA试剂盒) induces beta cells apoptosis via an NF-kappaB (显示 NFKB1 ELISA试剂盒)/Bcl2-dependent mitochondrial pathway.
Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.
The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes
the augmentation of endogenous MTA1 (显示 MTA1 ELISA试剂盒) expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (显示 ESR1 ELISA试剂盒) and BCL2 pathways.
These results suggest a role for mitochondrial p53 (显示 TP53 ELISA试剂盒) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (显示 BAX ELISA试剂盒) and Bcl2.
Zebrafish gene expressions of P53 (显示 TP53 ELISA试剂盒), Bcl-2, Bax (显示 BAX ELISA试剂盒) and caspase-3 (显示 CASP3 ELISA试剂盒) were elevated after exposure with microcystin-LR under different ambient temperatures.
Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (显示 S1PR1 ELISA试剂盒), and ICAM1 (显示 ICAM1 ELISA试剂盒) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.
Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (显示 COX2 ELISA试剂盒) and bcl2, but increased p53 (显示 TP53 ELISA试剂盒) expression.
Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (显示 NOTCH1 ELISA试剂盒) and fish bcl-2, indicating synergy between the Notch (显示 NOTCH1 ELISA试剂盒) pathway and the bcl2-mediated antiapoptotic pathway.
Over-expression of STC-1 (显示 STC1 ELISA试剂盒) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (显示 CASP3 ELISA试剂盒) production in the damaged cells. Findings from this study suggest that STC-1 (显示 STC1 ELISA试剂盒) plays a protective role in intestinal cells through an antioxidant mechanism.
BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (显示 BAX ELISA试剂盒) expression.
G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.
role of vascular endothelial growth factor receptor-1 (显示 FLT1 ELISA试剂盒) in Bcl-2 expression
apoptosis-inducing factor (显示 AIFM1 ELISA试剂盒) was expressed in luminal alveolar cells and, in concert with a change in bax (显示 BAX ELISA试剂盒) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax (显示 BAX ELISA试剂盒), Bcl-2, caspase-3 (显示 CASP3 ELISA试剂盒) and-7 cannot be used as a reliable apoptosis detection method.
These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.
bcl-2 and bax (显示 BAX ELISA试剂盒) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (显示 BAX ELISA试剂盒)]
excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (显示 CASP3 ELISA试剂盒) expression as well as low Bcl-2 expression.
These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (显示 BAX ELISA试剂盒) ratio through a mechanism involving protein kinase C (显示 PKC ELISA试剂盒).
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (显示 BAX ELISA试剂盒) and decreasing expression of bcl2.
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (显示 BAX ELISA试剂盒).
Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (显示 TP53 ELISA试剂盒) and decrease in the antiapoptotic BCl2 proteins.
Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (显示 CASP3 ELISA试剂盒).
Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
apoptosis regulator Bcl-2
, protein phosphatase 1, regulatory subunit 50
, B cell lymphoma 2 associated oncogene
, B-cell leukemia/lymphoma 2
, Bcl2-like protein
, BCL2B-cell CLL/lymphoma 2
, B-cell lymphoma protein 2
, B-cell CLL/lymphoma 2
, LOW QUALITY PROTEIN: apoptosis regulator Bcl-2
, Apoptosis regulator Bcl-2