anti-BCL2 (BCL2) 抗体产品概述

Full name:
anti-B-Cell CLL/lymphoma 2 抗体 (BCL2)
在www.antibodies-online.cn可供1076 B-Cell CLL/lymphoma 2 (BCL2) 抗体的37不同的供货商。 再加上,我们可以发BCL2 试剂盒 (50)BCL2 蛋白 (18)和数多这个蛋白质的别的产品。 总共1177 BCL2产品已列进来了。
别名:
AW986256, bcl-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50

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引用最多的anti-BCL2 抗体

  1. Human Polyclonal BCL2 Primary Antibody for IF, IHC (p) - ABIN388095 : Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010 (PubMed)
    Show all 19 references for 388095

  2. Human Monoclonal BCL2 Primary Antibody for FACS, IHC (fro) - ABIN118990 : Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991 (PubMed)
    Show all 4 references for 118990

  3. Human Monoclonal BCL2 Primary Antibody for FACS, WB - ABIN1105506 : Gallatin, Weissman, Butcher: A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for 1105506

  4. Human Monoclonal BCL2 Primary Antibody for IHC (fro), IF - ABIN1105504 : Ngan, Chen-Levy, Weiss, Warnke, Cleary: Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. in The New England journal of medicine 1988 (PubMed)
    Show all 2 references for 1105504

  5. Human Monoclonal BCL2 Primary Antibody for FACS - ABIN1105508 : Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: Resistance to Fas-mediated apoptosis in human lung fibroblast. in The European respiratory journal 2002 (PubMed)
    Show all 2 references for 1105508

  6. Human Polyclonal BCL2 Primary Antibody for IHC, ELISA - ABIN1531302 : Cleary, Smith, Sklar: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. in Cell 1986 (PubMed)

  7. Human Polyclonal BCL2 Primary Antibody for WB - ABIN657744 : Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. in Cancer cell 2010 (PubMed)

  8. Human Polyclonal BCL2 Primary Antibody for EIA, IHC (p) - ABIN356812 : Liu, Zhou, Li, Sun, Lin, Lang, He, Cao, Yan, Wang, Lu, Han, Cao, Zhang, Zeng: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. in Cancer research 2008 (PubMed)

  9. Human Polyclonal BCL2 Primary Antibody for IHC, WB - ABIN2792106 : Chen, Valencia, Zhong, McColl, Roderick, Bootman, Berridge, Conway, Holmes, Mignery, Velez, Distelhorst: Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. in The Journal of cell biology 2004 (PubMed)

更多抗BCL2的相互作用对抗体

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. an essential role for the binding of BCL2 to BIM (显示 BCL2L11 抗体) in the survival of noncycling NK cells.

  2. LIGHT signalling pathway combined with IFN-gamma (显示 IFNG 抗体) induces beta cells apoptosis via an NF-kappaB (显示 NFKB1 抗体)/Bcl2-dependent mitochondrial pathway.

  3. Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.

  4. The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes

  5. the augmentation of endogenous MTA1 (显示 MTA1 抗体) expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (显示 ESR1 抗体) and BCL2 pathways.

  6. Interestingly, SKPs showed higher protein levels of Bcl-2, Nrf2 (显示 NFE2L2 抗体), and HO-1 (显示 HMOX1 抗体) than FBs (显示 FBS 抗体). SKPs exert a beneficial effect on resisting UVB-induced apoptosis, which may be associated with Bcl-2 and Nrf2 (显示 NFE2L2 抗体) upregulation.

  7. Bcl-2 is an essential regulator in the survival of doublecortin (显示 DCX 抗体)-expressing immature neurons.

  8. Results show that the deletion of BCL-2, on its own or in concert with MCL-1 (显示 MCL1 抗体), does not affect platelet production or platelet lifespan.

  9. the expression changes observed within the BCL2 family did not depend on STAT3 (显示 STAT3 抗体) signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (显示 STAT5A 抗体).

  10. Bcl-2-caspase-9 (显示 CASP9 抗体) apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related proteins.

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. bcl-2 and bax (显示 BAX 抗体) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (显示 BAX 抗体)]

Human B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Overview of the pleiotropic functions of BCL2 mediated by its physical binding interaction with other proteins and the various ways BCL2 mutations would affect the normal function of the cell leading to the development of diffuse large B-cell lymphomas (review).

  2. Diffuse large B-cell lymphoma with concurrent high MYC (显示 MYC 抗体) and BCL2 expression shows evidence of active B-cell receptor signaling

  3. Case Reports: BCL2 gene translocations are a recurrent feature of a distinct subset of histiocytic sarcomas that are associated with follicular lymphoma.

  4. This study provides evidence that the homozygous BCL2-938 CC genotype is associated with OS and C in prostate cancer patients.

  5. In Diffuse large B-cell lymphoma (DLBCL) evaluation from Taiwan, the relative frequency of germinal center B-cell tumors among DLBCL was low in most East Asian countries. There is a wide range of BCL2 rearrangement rates, higher in the West and lower in East Asia.

  6. Two Distinct BCL2 Rearrangements, Each Observed in 2 Independent Subclones, Evolving from a Founder Clone with Trisomy 12 in a Unique Case of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

  7. BCL2 scoring system could readily be used by pathologists to evaluate patients with diffuse large B-cell lymphoma who might benefit from BCL2-targeted therapies.

  8. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (显示 BCL2L1 抗体) on the priming of Bax (显示 BAX 抗体). As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (显示 BCL2L1 抗体), and of Bcl-2, is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  9. In the current report, we extend the understanding of the role of BCL2 in HIV infection by demonstrating that BCL2 is necessary for maintaining HIV in the settings of homeostatic proliferation of infected cell lines and acute spreading infection of primary CD4 (显示 CD4 抗体) T cells.

  10. we indicated that miR (显示 MLXIP 抗体)-34a can inhibit tumor invasion and metastasis in osteosarcoma, and its mechanism may be partly related to downregulating the expression of C-IAP2 (显示 BIRC3 抗体) and Bcl-2 protein directly or indirectly.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Over-expression of STC-1 (显示 STC1 抗体) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (显示 CASP3 抗体) production in the damaged cells. Findings from this study suggest that STC-1 (显示 STC1 抗体) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (显示 BAX 抗体) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (显示 FLT1 抗体) in Bcl-2 expression

  5. apoptosis-inducing factor (显示 AIFM1 抗体) was expressed in luminal alveolar cells and, in concert with a change in bax (显示 BAX 抗体) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (显示 BAX 抗体), Bcl-2, caspase-3 (显示 CASP3 抗体) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (显示 CASP3 抗体) expression as well as low Bcl-2 expression.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (显示 BAX 抗体) ratio through a mechanism involving protein kinase C (显示 PKC 抗体).

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (显示 BAX 抗体) and decreasing expression of bcl2.

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (显示 BAX 抗体).

  5. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (显示 TP53 抗体) and decrease in the antiapoptotic BCl2 proteins.

  6. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (显示 CASP3 抗体).

  7. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. These results suggest a role for mitochondrial p53 (显示 TP53 抗体) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (显示 BAX 抗体) and Bcl2.

  2. Zebrafish gene expressions of P53 (显示 TP53 抗体), Bcl-2, Bax (显示 BAX 抗体) and caspase-3 (显示 CASP3 抗体) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (显示 S1PR1 抗体), and ICAM1 (显示 ICAM1 抗体) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (显示 COX2 抗体) and bcl2, but increased p53 (显示 TP53 抗体) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (显示 NOTCH1 抗体) and fish bcl-2, indicating synergy between the Notch (显示 NOTCH1 抗体) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 抗原简介

Antigen Summary

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) 抗体
  • B-cell CLL/lymphoma 2 (LOC100224888) 抗体
  • B cell leukemia/lymphoma 2 (Bcl2) 抗体
  • B-cell CLL/lymphoma 2 (Bcl2) 抗体
  • B-cell CLL/lymphoma 2 protein (BCL-2) 抗体
  • B-cell leukemia/lymphoma 2 (bcl2) 抗体
  • AW986256 抗体
  • bcl-2 抗体
  • Bcl2 抗体
  • C430015F12Rik 抗体
  • D630044D05Rik 抗体
  • D830018M01Rik 抗体
  • PPP1R50 抗体

Protein level used designations for BCL2

B-cell lymphoma protein 2 , B-cell leukemia/lymphoma 2 , apoptosis regulator Bcl-2 , B-cell CLL/lymphoma 2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , Bcl2-like protein , BCL2B-cell CLL/lymphoma 2 , PCKBCL2 , Bcl2 , zBlp2

GENE ID SPECIES
738409 Pan troglodytes
100224888 Taeniopygia guttata
12043 Mus musculus
100733337 Cavia porcellus
596 Homo sapiens
24224 Rattus norvegicus
403416 Canis lupus familiaris
493934 Felis catus
100049703 Sus scrofa
281020 Bos taurus
396282 Gallus gallus
100009447 Oryctolagus cuniculus
570772 Danio rerio
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