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抗Human RAD1 抗体:
抗Mouse (Murine) RAD1 抗体:
抗Rat (Rattus) RAD1 抗体:
Dominant alleles of RAD51 (显示 RAD51 抗体), TP53 (显示 TP53 抗体) and XRCC1 (显示 XRCC1 抗体) combined genotypes indicated a strong protective role against hereditary breast cancer.
Intramolecular binding of the rad9 (显示 RAD9A 抗体) C-terminus in the checkpoint clamp (显示 PDZK1 抗体) Rad9 (显示 RAD9A 抗体)-Hus1 (显示 HUS1 抗体)-Rad1 (显示 ERCC4 抗体) is closely linked with its DNA binding.
Data show models for the ternary PCNA (显示 PCNA 抗体)/FEN1 (显示 FEN1 抗体)/DNA and Rad9 (显示 RAD9A 抗体)-Rad1 (显示 ERCC4 抗体)-Hus1 (显示 HUS1 抗体) (9-1-1 complex)/FEN1 (显示 FEN1 抗体)/DNA assemblies.
The RAD1 (显示 ERCC4 抗体) is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.
CK2 (显示 CSNK2A1 抗体) plays a crucial role in the ATR (显示 ANTXR1 抗体)-dependent checkpoint pathway through its ability to phosphorylate Ser (显示 SIGLEC1 抗体)-341 and Ser (显示 SIGLEC1 抗体)-387 of the Rad9 (显示 RAD9A 抗体) subunit of the Rad9 (显示 RAD9A 抗体)-Hus1 (显示 HUS1 抗体)-Rad1 (显示 ERCC4 抗体) complex
Rad9 (显示 RAD9A 抗体)-Rad1 (显示 ERCC4 抗体)-Hus1 (显示 HUS1 抗体) complex enhances in vitro activity of 8-oxoguanine DNA glycosylase (显示 OGG1 抗体).
Rad9 (显示 RAD9A 抗体), Hus1 (显示 HUS1 抗体), and Rad1 (显示 ERCC4 抗体) heterotrimeric complex chromatin binding is a proximal event in the checkpoint signaling cascade
RAD1 (显示 ERCC4 抗体) is a potential intrinsic chaperone in the stabilization of HUS1 (显示 HUS1 抗体) for the heterotrimeric (RAD9 (显示 RAD9A 抗体)-RAD1 (显示 ERCC4 抗体)-HUS1 (显示 HUS1 抗体)) checkpoint complex formation.
The human Rad9 (显示 RAD9A 抗体)/Rad1 (显示 ERCC4 抗体)/Hus1 (显示 HUS1 抗体) complex interacts with and stimulates DNA polymerase beta (显示 POLB 抗体) activity.
complex with rad9 (显示 RAD9A 抗体) and hus1 (显示 HUS1 抗体) is a damage-specific activator of flap endonuclease 1 (显示 FEN1 抗体)
HUS1 (显示 HUS1 抗体) acts as a component of the canonical 9-1-1 complex during meiotic prophase I to promote DSB repair and further propose that RAD1 and TOPBP1 (显示 TOPBP1 抗体) respond to unsynapsed chromatin through an alternative mechanism that does not require RAD9 (显示 RAD9A 抗体) or HUS1 (显示 HUS1 抗体).
The rad1 protein is required for repairing DNA lesions induced by UV-light, HU and gamma rays, and for mediating G(2)/M and S/M checkpoint controls.
data indicate that Rad1(K185) is not a functional counterpart of PCNA (显示 PCNA 抗体)(K164).
data suggest that Mrad1 is important for preventing tumor development.
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
DNA repair exonuclease REC1
, DNA repair exonuclease rad1 homolog
, cell cycle checkpoint protein Hrad1
, cell cycle checkpoint protein RAD1
, checkpoint control protein HRAD1
, exonuclease homolog RAD1
, rad1-like DNA damage checkpoint protein
, RAD1 homolog (S. pombe)
, RAD1 homolog
, Cell cycle checkpoint protein RAD1
, cell cycle checkpoint protein rad1