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抗Mouse (Murine) Interleukin 6 抗体:
抗Rat (Rattus) Interleukin 6 抗体:
抗Human Interleukin 6 抗体:
Human Monoclonal Interleukin 6 Primary Antibody for FACS - ABIN1383944
Lu, Brochier, Wijdenes, Brailly, Bataille, Klein: High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo. in European journal of immunology 1992
Show all 60 Pubmed References
Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042620
Xu, Feng, Wang, Zhu, Lin, Lou, Xiang, He, Zheng, Tang, Zuo: Phytoestrogen calycosin-7-O-?-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. in Journal of cellular biochemistry 2011
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Rat (Rattus) Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042526
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 17 Pubmed References
Human Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3043090
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for ELISA, WB - ABIN3043248
Shi, Song, Zhang, Li, Li: Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients. in Experimental and therapeutic medicine 2013
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Human Polyclonal Interleukin 6 Primary Antibody for WB - ABIN3042806
Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. in International journal of clinical and experimental pathology 2015
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Human Polyclonal Interleukin 6 Primary Antibody for ICC, IF - ABIN269335
Bottino, Balamurugan, Tse, Thirunavukkarasu, Ge, Profozich, Milton, Ziegenfuss, Trucco, Piganelli: Response of human islets to isolation stress and the effect of antioxidant treatment. in Diabetes 2004
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Human Monoclonal Interleukin 6 Primary Antibody for CyTOF, FACS - ABIN4900155
Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. in The Journal of allergy and clinical immunology 2009
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Human Monoclonal Interleukin 6 Primary Antibody for CyTOF, FACS - ABIN4900156
Rodier, Coppé, Patil, Hoeijmakers, Muñoz, Raza, Freund, Campeau, Davalos, Campisi: Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. in Nature cell biology 2009
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody for IF (p), IHC (p) - ABIN739385
Li, Dan, Nie, Hu, Gesang, Bianba, Ze, Ciren: CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts. in Molecular medicine reports 2015
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HDAC3 (显示 HDAC3 抗体)-deficient chondrocytes exhibited increased expression of cytokine and matrix-degrading genes (Il-6, Mmp3 (显示 MMP3 抗体), Mmp13 (显示 MMP13 抗体), and Saa3) and a reduced abundance of genes related to extracellular matrix production, bone development, and ossification (Acan (显示 ACAN 抗体), Col2a1 (显示 COL2A1 抗体), Ihh (显示 IHH 抗体), and Col10a1 (显示 COL10A1 抗体)).
Our study is the first to show the important role of IL-6 in regulating cardiac pathogenesis via inflammation and apoptosis during AngII-induced hypertension. We also provide a novel link between IL-6/STAT3 (显示 STAT3 抗体) and EndoG (显示 ENDOG 抗体)/MEF2A (显示 MEF2A 抗体) pathway that affects cardiac hypertrophy during AngII stimulation.
It enhances hepatic ketogenesis via 3-hydroxy-3-methylglutary-CoA synthase 2 signaling activation by p38 (显示 CRK 抗体)/nuclear factor kappaB p65 (显示 NFkBP65 抗体).
found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27 (显示 IL27 抗体)
results suggest that IL-6 plays an important but limited role in AAA (显示 AAAS 抗体) pathogenesis, and primarily regulates cell migration and infiltration
The analysis points to a critical role for Hoxa9 (显示 HOXA9 抗体) and PU.1 in distal regulation of c-myb (显示 MYB 抗体) expression in murine myeloid cells during iL-6-induced cell differentiation.
these findings suggested that IL6 gene deficiency antagonized HFD-induced bone loss.
Long-term exposure to atmospheric particulates, PM2.5 up-regulated H3K4 and H3K9 methylation in IL-6 and IFN-beta (显示 IFNB1 抗体) promoter regions through down-regulating Kdm6a (显示 KDM6A 抗体) expression. The results suggest that short-term exposure to PM2.5 significantly enhances the survival rate of influenza A-contaminated mice, while long-term PM2.5 inhalation lowers the capacity of pulmonary macrophages to secrete IL-6 and IFN-beta (显示 IFNB1 抗体).
This study suggests direct stimulation of autophagy as a novel mechanism for IL-6-mediated protection of beta cells from stress-induced apoptosis.
Internalized CpG oligodeoxynucleotide (ODN)-conjugated PPMs (PPM-CpG) greatly enhance the induction of selected cytokines (TNF-alpha (显示 TNF 抗体) and IL-6) in RAW 264.7 cells compared to that by the soluble CpG ODN and ionic complexes.
Interleukin-6 is a potential biomarker for the differential diagnosis of bacterial meningitis.
IL-6 and TIE2 (显示 TEK 抗体) polymorphisms are associated with baseline peritoneal transport property.
IL6 and PRG4 (显示 PRG4 抗体) represent potential novel tissue biomarkers of disease severity and prognosis in conjunctival fibrosis after glaucoma surgery.
Results showed that IL-6 promoter regulates the transcription of RelA (显示 NFkBP65 抗体) with phosphosites pSer42 and pSer45 seems to play a role in this regulation.
The levels of IL-1 (显示 IL1A 抗体), IL-6 and TNF-alpha (显示 TNF 抗体) in GCF (显示 GUCY2F 抗体) were higher in patients with ischemic stroke but the difference was not significant. In conclusion, ischemic stroke was found to be associated with higher levels of IL-1beta (显示 IL1B 抗体) and IL-6 in serum
These results support the emerging potential of CaSR (显示 CASR 抗体) as a therapeutic target in metastatic breast cancer whose pharmacological modulation would reduce IL-6.
IL6 expression was significantly higher in the cortex of asphyctic suicide subjects than in non-suicidal asphyxia and controls.
The gene polymorphism of Interleukin-6 -174 C and G allele are an risk factor for diabetes, but gene polymorphism of Interleukin-6 -174 G > C is not an independent risk factor for diabetic foot.
The expression of IL-1beta (显示 IL1B 抗体) and IL-6 during leprosy reactions did not differ significantly between tissues obtained from leprosy patients with and without HIV coinfection.
Elevated levels of systemic IFNgamma and IL-6 implied that the CEACAM5 (显示 CEACAM5 抗体)-specific T cells had undergone immune activation in vivo but only in patients receiving high-intensity pre-conditioning.
STA3 (显示 ARHGEF3 抗体) facilitates TLR4 (显示 TLR4 抗体)-dependent IL-6 and IL-8 (显示 IL8 抗体) production via IL-6 receptor-positive feedback in endometrial cells.
when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.
The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 抗体) and PTGS2 (显示 PTGS2 抗体), and decreased the expression of SOD2 (显示 SOD2 抗体), GPX3 (显示 GPX3 抗体), DAB2 (显示 DAB2 抗体), and NR3C1 (显示 NR3C1 抗体). TNF (显示 TNF 抗体) and IL6 levels were also decreased while those of NAMPT (显示 NAMPT 抗体) were unaffected.
Testicular IL-1 alpha (显示 IL1A 抗体) and IL-1 beta (显示 IL1B 抗体) concentrations were highest in the early post-natal period; however, IL-1 (显示 IL1A 抗体) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.
The results showed that the expression of TNF-alpha (显示 TNF 抗体), iNOS (显示 NOS2 抗体), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (显示 IL12A 抗体) was unaffected.[IL-6, IL-12 (显示 IL12A 抗体)]
results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (显示 IFNAR1 抗体) (sIL (显示 STIL 抗体)-6R), induces activation of JAK1 (显示 JAK1 抗体), JAK2 (显示 JAK2 抗体), and STAT1 (显示 STAT1 抗体)/STAT3 (显示 STAT3 抗体) proteins in bovine articular chondrocytes.
Mechanical injury potentiates the catabolic effects of TNFalpha (显示 TNF 抗体) and IL-6/sIL (显示 STIL 抗体)-6R in causing proteoglycan (显示 Vcan 抗体) degradation in human and bovine cartilage.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta (显示 IL1B 抗体) and IL-6 in rabbit cornea cells.
we showed that IL-6 did not directly promote the proliferation of theca interna cells.
Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (显示 HIF1A 抗体)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (显示 TGFB1 抗体), IL-10 (显示 IL10 抗体), and IL-6 in ovarian follicles are reported.
Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (显示 STAT3 抗体) (signal transducer/activator of transcription (显示 STAT1 抗体) 3) signaling pathway (including up-regulation of STAT3 (显示 STAT3 抗体) expression/phosphorylation).
LIF (显示 LIF 抗体) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.
INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.
interleukin-6, endothelin ET-1 (显示 EDN1 抗体), and apoptotic Bak (显示 BAK1 抗体) and Bcl-XL (显示 BCL2L1 抗体) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Data show that all five molecules, BNP (显示 BNC2 抗体), ICAM-1 (显示 ICAM1 抗体), TNF-alpha (显示 TNF 抗体), VCAM-1 (显示 VCAM1 抗体) and IL-6, quickly and reliably signaled adverse interactions.
IL-6 level from frozen peripheral blood mononuclear cells was significantly lower than that from fresh ones.
These results suggest that TNF-alpha (显示 TNF 抗体) and IL-10 (显示 IL10 抗体), but not IL-6, are involved in the late reparatory phases of the experimental disk lesion.
Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.
These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.
IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (显示 WNT2 抗体) signaling pathway transactivator beta-catenin (显示 CTNNB1 抗体), induced expression of inhibitors of the Wnt (显示 WNT2 抗体) pathway, and increased expression of GDF-5 (显示 GDF5 抗体).
study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (显示 ADORA2B 抗体) activation and that this effect can be modulated by A2AAR (显示 ADORA2A 抗体)
Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.
Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.
Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (显示 IL10 抗体) alone, were useful diagnostic indices of sepsis in equine neonates.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (显示 IL10 抗体) and TNF-alpha (显示 TNF 抗体), in horses with recurrent airway obstruction during exacerbation and in remission is reported.
IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.
in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout
found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (显示 KRT12 抗体)), are potent inducers of IL-1beta (显示 IL1B 抗体) and IL-6 gene expression and were equal to, or more potent than, crude LPS (显示 IRF6 抗体).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
B-cell hybridoma growth factor
, interleukin HP-1
, Interleukin 6 (interferon, beta 2)
, B-cell differentiation factor
, B-cell stimulatory factor 2
, CTL differentiation factor
, hybridoma growth factor
, interferon beta-2
, interleukin BSF-2
, interleukin-6 protein