Spleen tyrosine Kinase (SYK) ELISA试剂盒产品概述

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Spleen tyrosine Kinase ELISA试剂盒 (SYK)
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别名:
p72-Syk, p72syk, Sykb

适于 Spleen tyrosine Kinase 相互作用对的更多 ELISA 试剂盒

Human Spleen tyrosine Kinase (SYK) interaction partners

  1. study demonstrates that high SYK expression is a common feature of CD21 (显示 CR2 ELISA试剂盒)(low) B cells independent of the underlying disorder, and that this high expression is sufficient to drive constitutive phosphorylation of SYK and its immediate targets Bruton's tyrosine kinase (显示 BTK ELISA试剂盒) and phospholipase Cgamma2

  2. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (显示 IL1B ELISA试剂盒) responses in a TLR2 (显示 TLR2 ELISA试剂盒)- and FcgammaR-dependent fashion. FcgammaR-mediated Syk activation leads to NLRP3 (显示 NLRP3 ELISA试剂盒) inflammasome-dependent IL-1beta (显示 IL1B ELISA试剂盒) production in macrophages.

  3. High SYK expression is associated with lymphangioleiomyomatosis.

  4. NKp65 utilizes a hemi-immunoreceptor tyrosine-based activation motif -like motif for cellular activation that requires Syk, although Syk appears not to be recruited to NKp65.

  5. Syk is a key regulator of Hoxa9 (显示 HOXA9 ELISA试剂盒)/Meis1 (显示 MEIS1 ELISA试剂盒)-driven acute myeloid leukemia (显示 BCL11A ELISA试剂盒).

  6. Data show that spleen tyrosine kinase (SYK) and proto-oncogene (显示 RAB1A ELISA试剂盒) protein c (显示 PROC ELISA试剂盒)-akt (AKT1 (显示 AKT1 ELISA试剂盒)) proteins were increased in the cytoplasm of the cells forming Mallory-Denk bodies.

  7. B cell receptor signaling component, SYK, caused PAX5 (显示 PAX5 ELISA试剂盒) tyrosine phosphorylation in vitro and in cells. Transcriptional repression on the BLIMP1 (显示 PRDM1 ELISA试剂盒) promoter by PAX5 (显示 PAX5 ELISA试剂盒) was attenuated by this phosphorylation.

  8. Pharmacological inhibitors of SYK activity significantly reduced the engulfment of oxLDL microbeads in the presence of serum factors, but had little effect on IgG phagocytosis.

  9. our data strongly suggest that AQCA-mediated suppression of inflammatory responses could be managed by a direct interference of signaling cascades including IRAK (显示 IRAK1 ELISA试剂盒) and Syk, linked to the activation of NF-kappaB (显示 NFKB1 ELISA试剂盒) and AP-1 (显示 FOSB ELISA试剂盒).

  10. a potential link between the upregulation of Syk and VEGF-C (显示 VEGFC ELISA试剂盒) expression and lung adenocarcinoma.

Mouse (Murine) Spleen tyrosine Kinase (SYK) interaction partners

  1. ephrin B3 (显示 EFNB3 ELISA试剂盒)/EphB2 (显示 EPHB2 ELISA试剂盒) are obvious candidates for driving the Syk-dependent repulsive response.

  2. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (显示 IL1B ELISA试剂盒) responses in a TLR2 (显示 TLR2 ELISA试剂盒)- and FcgammaR-dependent fashion. FcgammaR-mediated Syk activation leads to NLRP3 (显示 NLRP3 ELISA试剂盒) inflammasome-dependent IL-1beta (显示 IL1B ELISA试剂盒) production in macrophages.

  3. The effect of Smad4 (显示 SMAD4 ELISA试剂盒) was at least partially mediated by the downstream effectors Syk and ROCK2 (显示 ROCK2 ELISA试剂盒) transcription in megakaryocytes.

  4. Gene expression analysis of lung tissues revealed that HDM (显示 HDAC3 ELISA试剂盒)-induced expression of IL-17 (显示 IL17A ELISA试剂盒) and CXCL-1 (显示 CXCL1 ELISA试剂盒) was significantly attenuated in both Sykdel/del and GSK143-treated mice. CONCLUSION: Syk inhibitors may play a role in the management of neutrophilic asthma

  5. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI (显示 GP6 ELISA试剂盒).

  6. Pharmacological Syk inhibition might provide a safe therapeutic strategy to prevent arterial thrombosis and to limit infarct progression in acute stroke.

  7. Studies indicate that SHP1 (显示 PTPN6 ELISA试剂盒) and SYK crosstalk as a critical regulator of MyD88 (显示 MYD88 ELISA试剂盒) post-translational modifications and IL-1 (显示 IL1A ELISA试剂盒)-driven inflammation.

  8. dephosphorylation of Tyr (显示 TYR ELISA试剂盒)(P)(346) may be considered an important "checkpoint" in the regulation of Syk activation process. Putative biological functions of TULA-2 (显示 STS1 ELISA试剂盒)-mediated dephosphorylation of Tyr (显示 TYR ELISA试剂盒)(P)(346) may include deactivation of receptor-activated Syk or suppression of Syk activation by suboptimal stimulation.

  9. These studies define a pathologic role for myeloid Syk signaling in renal ischemia/reperfusion injury

  10. Torreya nucifera butanol fraction exhibits anti-inflammatory activities by direct inhibition of macrophage Src (显示 SRC ELISA试剂盒)/Syk/NF-kappaB (显示 NFKB1 ELISA试剂盒) and IRAK1 (显示 IRAK1 ELISA试剂盒)/AP-1 (显示 JUN ELISA试剂盒) signaling.

Cow (Bovine) Spleen tyrosine Kinase (SYK) interaction partners

  1. These data suggest that Syk mRNA expression dynamics is closely related to bovine leukemia virus-induced disease.

Spleen tyrosine Kinase (SYK) 抗原简介

Antigen Summary

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen tyrosine Kinase (SYK)

  • Tyrosine-protein kinase SYK (ksyk) Elisa Kit
  • spleen tyrosine kinase (SYK) Elisa Kit
  • spleen tyrosine kinase (Syk) Elisa Kit
  • p72-Syk Elisa Kit
  • p72syk Elisa Kit
  • Sykb Elisa Kit

Protein level used designations for SYK

Tyrosine-protein kinase SYK , tyrosine-protein kinase SYK , protein-tyrosine kinase

GENE ID SPECIES
100380388 Salmo salar
6850 Homo sapiens
20963 Mus musculus
25155 Rattus norvegicus
484196 Canis lupus familiaris
100125540 Sus scrofa
515515 Bos taurus
427272 Gallus gallus
100716985 Cavia porcellus
100345556 Oryctolagus cuniculus
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