PLG 蛋白 (PLG)产品概述

Full name:
Plasminogen 蛋白 (PLG)
在www.antibodies-online.cn可供69 Plasminogen (PLG) 蛋白的10不同的供货商。 再加上,我们可以发PLG 抗体 (508)PLG 试剂盒 (109)和数多这个蛋白质的别的产品。 总共699 PLG产品已列进来了。
别名:
Ab1-346, AI649309, LPA, Pg, plg, wu:fb70e09
列出全部蛋白 基因 基因ID UniProt
PLG 5340 P00747
PLG 85253 Q01177
PLG 18815 P20918

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引用最多的PLG 蛋白

  1. Human PLG Protein expressed in Human - ABIN491018 : Komissarov, Florova, Idell: Effects of extracellular DNA on plasminogen activation and fibrinolysis. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 references for 491018

  2. Cow (Bovine) PLG Protein expressed in Bovine - ABIN491395 : Coy, Jiménez-Movilla, García-Vázquez, Mondéjar, Grullón, Romar: Oocytes use the plasminogen-plasmin system to remove supernumerary spermatozoa. in Human reproduction (Oxford, England) 2012 (PubMed)

  3. Horse (Equine) PLG Protein expressed in Horse - ABIN780187 : Velineni, Timoney: Characterization and protective immunogenicity of the SzM protein of Streptococcus zooepidemicus NC78 from a clonal outbreak of equine respiratory disease. in Clinical and vaccine immunology : CVI 2013 (PubMed)

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Human Plasminogen (PLG) interaction partners

  1. Data suggest that protein aggregates interact with tissue-type plasminogen activator and plasminogen to efficiently generate plasmin; this aggregate-bound plasmin is shielded from inhibition by alpha-2-antiplasmin and degrades protein aggregates to release smaller, soluble but relatively hydrophobic peptide fragments; these fragments bind to and are cytotoxic to microglia (by not vascular endothelial cells).

  2. The mechanism for plasminogen/M protein binding uncovered here may facilitate targeting of group A Streptococcus pyogenes virulence factors for disease management

  3. t-PA (显示 PLAT 蛋白) binds to Lys91 in the MBP (显示 MBL2 蛋白) NH2-terminal region and PLG binds to Lys122 in the MBP (显示 MBL2 蛋白) COOH-terminal region. This proximity promotes the activation of PLG by t-PA (显示 PLAT 蛋白).

  4. in the presence of platelet polyphosphate and the downstream substrate fibrin, alphaFXIIa is a highly efficient and favorable plasminogen activator.

  5. Plasmin(ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer

  6. Our findings indicate a new pathway for bradykinin formation in patients with HAE, in which FXII (显示 F12 蛋白) is cleaved and activated by plasmin.

  7. VWF (显示 VWF 蛋白) susceptibility to plasmin proteolysis at K1491-R1492 is modulated by local N-linked glycan expression within A1A2A3, and specifically inhibited by heparin binding to the A1 domain.

  8. Plasminogen and P4HA2 (显示 P4HA2 蛋白) are involved in vascular remodelling and angiogenesis, suggesting a high relevance of these processes for the pathogenic mechanisms underlying this type of vasculitis

  9. Plasminogen and OxPL-PLG were lower in patients presenting with an acute MI than in those with stable CAD and also in those with atherothrombotic MI (Type 1) vs. those with non-atherothrombotic MI (Type 2).

  10. Although carriers with PLG:p.Ala620Thr show low plasminogen activity, this is not a predisposing variant for aHUS; and individuals of dysplasminogenemia are not at significantly increased risk of aHUS.

Cow (Bovine) Plasminogen (PLG) interaction partners

  1. The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte.

  2. The current study suggests the existence of an active TNF-alpha (显示 TNF 蛋白)-plasminogen-plasmin autocrine/paracrine loop on the massively infiltrated polymorphonuclear neutrophils inside udders of drying-off cows.

  3. examination of interaction with streptococcal plasminogen activator PauA

Pig (Porcine) Plasminogen (PLG) interaction partners

  1. The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte.

Mouse (Murine) Plasminogen (PLG) interaction partners

  1. confirmed the ability of Plg/Pla to both promote efferocytosis and override the prosurvival effect of LPS (显示 TLR4 蛋白) via annexin A1 (显示 ANXA1 蛋白).

  2. findings identify plasmin as a decisive checkpoint in the inflammatory response during Macrophage activation syndrome (MAS (显示 MAS1 蛋白)) and a potential novel therapeutic target for MAS (显示 MAS1 蛋白).

  3. Deficiency of plasminogen delays onset of autoimmune neuroinflammatory disease and protects from the development of paralysis.

  4. Plasminogen may regulate DPP-4 (显示 DPP4 蛋白) activity and glucose metabolism.

  5. Plasminogen-deficient mice frequently develop colon lesions and rectal prolapses.

  6. manganese transport protein (显示 SLC11A2 蛋白) C (显示 PROC 蛋白) (MntC) is an extracellular matrix- and plasminogen-binding protein (显示 ENO1 蛋白)

  7. Plg from mouse plasma contains oxPtdPC adducts that are not affected by the action of Lp-PLA(2 (显示 Lp-PLA2 蛋白)), suggesting that linkage to Plg protects oxPtdPCs from metabolism during their transport in the plasma.

  8. plg-/- and tPA (显示 PLAT 蛋白)-/- mice exhibit brain parenchymal fibrin deposits that appear to result from reduced neurovascular integrity

  9. plasminogen-dependent proteolysis has a beneficial effect during neurological recovery after stroke.

  10. Pla-induced mononuclear cell recruitment in vivo was dependent on protease-activated receptor-1 activation of the MEK/ERK/NF-kappaB pathway, which led to the release of CCL2 and activation of CCR2.

蛋白简介PLG

蛋白简介

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PLG

  • plasminogen (plg)
  • plasminogen (PLG)
  • plasminogen (Plg)
  • plasminogen-like (LOC100725098)
  • plasminogen-like (LOC100050531)
  • Ab1-346 蛋白
  • AI649309 蛋白
  • LPA 蛋白
  • Pg 蛋白
  • plg 蛋白
  • wu:fb70e09 蛋白

Protein level used designations for Plasminogen 蛋白 (PLG)

plasminogen , plasmin , lipoprotein, Lp(a) , angiostatin , plasmin heavy chain A , plasmin light chain B

GENE ID SPECIES
322691 Danio rerio
463117 Pan troglodytes
100049487 Oryzias latipes
100136085 Oncorhynchus mykiss
5340 Homo sapiens
403602 Canis lupus familiaris
101095261 Felis catus
280897 Bos taurus
85253 Rattus norvegicus
733660 Sus scrofa
18815 Mus musculus
421580 Gallus gallus
100357844 Oryctolagus cuniculus
703891 Macaca mulatta
100172984 Pongo abelii
100725098 Cavia porcellus
100050531 Equus caballus
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