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anti-FLASH (CASP8AP2) 抗体产品概述

Full name:
anti-CASP8 Associated Protein 2 抗体 (CASP8AP2)
在www.antibodies-online.cn可供50 CASP8 Associated Protein 2 (CASP8AP2) 抗体的14不同的供货商。 再加上,我们可以发FLASH 试剂盒 (7)和数多这个蛋白质的别的产品。 总共60 FLASH产品已列进来了。
别名:
AA387232, CASP8AP2, CED-4, D4Ertd659e, fc74h10, FLASH, mKIAA1315, RIP25, wu:fc74h10, zgc:113449
列出全部抗体 基因 基因ID UniProt
CASP8AP2 9994 Q9UKL3
CASP8AP2 26885 Q9WUF3
CASP8AP2 313128  

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抗Human FLASH 抗体:

抗Mouse (Murine) FLASH 抗体:

抗Rat (Rattus) FLASH 抗体:

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引用最多的anti-FLASH 抗体

  1. Cow (Bovine) Polyclonal FLASH Primary Antibody for WB - ABIN2784233 : Lee, Pi, Lee: Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis. in Biotechnology letters 2008 (PubMed)
    Show all 2 references for ABIN2784233

  2. Human Polyclonal FLASH Primary Antibody for ICC, IF - ABIN4312087 : Chen, Evans, Evans: FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal FLASH Primary Antibody for EIA, IF - ABIN499842 : Imai, Kimura, Murakami, Yajima, Sakamaki, Yonehara: The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. in Nature 1999 (PubMed)

更多抗FLASH的相互作用对抗体

Human CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. Our results indicate that the APAF1 (显示 APAF1 抗体), BAX (显示 BAX 抗体), and FLASH genes not only harbor frameshift mutations but also demonstrate mutational ITH, which together might play a role in the tumorigenesis of CRC (显示 CALR 抗体) with MSI (显示 MSI1 抗体)-H by affecting the apoptosis of cancer cells.

  2. High-quality solution NMR structures of three homeodomains from human proteins ALX4 (显示 ALX4 抗体), ZHX1 (显示 ZHX1 抗体) and CASP8AP2 were solved.

  3. the predictive values regarding low expressions of H2AFZ (显示 H2AFZ 抗体) and CASP8AP2 and high white blood cell count suggest that these features could help to identify more accurately patients at greater risk of relapse.

  4. ARS2 (显示 SRRT 抗体) and CASP8AP2 expressions can precisely predict high-risk of relapse and ALL prognosis.

  5. The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT (显示 NPAT 抗体) orthologues, thus acting as a signal targeting proteins to histone locus bodies.

  6. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (显示 PML 抗体) bodies.

  7. Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.

  8. FLASH/Lsm11 (显示 LSM11 抗体) complex bind a unique combination of polyadenylation factors

  9. These data demonstrate that methylation within the Casp8AP2 promoter correlates with the development of drug resistance and might serve as a biomarker and treatment target for drug resistance in cancer cells.

  10. FLASH knockdown in HT1080 (显示 CDC123 抗体) mutant cells defective in p53 (显示 TP53 抗体) did not significantly accelerate Fas (显示 FAS 抗体) mediated apoptosis indicating that the effect was dependent on functional p53 (显示 TP53 抗体).

Mouse (Murine) CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. the functional interaction of E2A (显示 TCF3 抗体) and FLASH play an important role in cell proliferation and cellular senescence via regulation of p21 (显示 D4S234E 抗体) expression in experimental glomerulonephritis.

  2. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (显示 PML 抗体) bodies.

FLASH (CASP8AP2) 抗原简介

Antigen Summary

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with FLASH (CASP8AP2)

  • caspase 8 associated protein 2 (CASP8AP2) 抗体
  • CASP8 associated protein 2 (casp8ap2) 抗体
  • CASP8 associated protein 2 (CASP8AP2) 抗体
  • CASP8 associated protein 2 (LOC100232114) 抗体
  • caspase 8 associated protein 2 (Casp8ap2) 抗体
  • AA387232 抗体
  • CASP8AP2 抗体
  • CED-4 抗体
  • D4Ertd659e 抗体
  • fc74h10 抗体
  • FLASH 抗体
  • mKIAA1315 抗体
  • RIP25 抗体
  • wu:fc74h10 抗体
  • zgc:113449 抗体

Protein level used designations for CASP8AP2

CASP8 associated protein 2 , caspase 8 associated protein 2 , CASP8-associated protein 2-like , CASP8-associated protein 2 , FLASH homolog RIP25 , FLICE associated huge , FLICE-associated huge protein , human FLASH

GENE ID SPECIES
421810 Gallus gallus
472070 Pan troglodytes
541521 Danio rerio
100065766 Equus caballus
100232114 Taeniopygia guttata
702294 Macaca mulatta
100342805 Oryctolagus cuniculus
100401726 Callithrix jacchus
100445558 Pongo abelii
100523759 Sus scrofa
9994 Homo sapiens
26885 Mus musculus
481921 Canis lupus familiaris
505138 Bos taurus
313128 Rattus norvegicus
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