You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Aurora A (AURKA) 抗体产品概述

Full name:
anti-Aurora Kinase A 抗体 (AURKA)
在www.antibodies-online.cn可供289 Aurora Kinase A (AURKA) 抗体的29不同的供货商。 再加上,我们可以发Aurora A 蛋白 (25)Aurora A 试剂盒 (2)和数多这个蛋白质的别的产品。 总共336 Aurora A产品已列进来了。
别名:
87A7-9/2, AIK, AIRK1, ARK-1, Ark1, AU019385, aur-a, AURA, aurka, aurka-a, Aurora-A, AURORA2, AW539821, Ayk1, BTAK, CG3068, ck10, ck[10], Dmel\\CG3068, Eg2, IAK, IAK1, l(3)87Ac, l(3)ck10, pEg2, PPP1R47, Stk6, STK7, STK15, wu:fb37c10, wu:fc02c02, zgc:100912
列出全部抗体 基因 基因ID UniProt
AURKA 6790 O14965
AURKA 20878 P97477
AURKA 261730  

显示所有的来源

显示所有的同义词

最受欢迎的抗anti-Aurora A (AURKA) 抗体

选择您的来源和应用

抗Human Aurora A 抗体:

抗Mouse (Murine) Aurora A 抗体:

抗Rat (Rattus) Aurora A 抗体:

所有可销售的anti-Aurora A 抗体

您会转到已过滤好的搜索

引用最多的anti-Aurora A 抗体

  1. Human Monoclonal Aurora A Primary Antibody for IF, WB - ABIN393835 : Molli, Li, Bagheri-Yarmand, Pakala, Katayama, Sen, Iyer, Chernoff, Tsai, Nair, Kumar: Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. in The Journal of cell biology 2010 (PubMed)
    Show all 5 references for ABIN393835

  2. Human Polyclonal Aurora A Primary Antibody for ICC, IF - ABIN151735 : Hontz, Li, Lingle, Negron, Bruzek, Salisbury, Li: Aurora a and B overexpression and centrosome amplification in early estrogen-induced tumor foci in the Syrian hamster kidney: implications for chromosomal instability, aneuploidy, and neoplasia. in Cancer research 2007 (PubMed)
    Show all 5 references for ABIN151735

  3. Cow (Bovine) Monoclonal Aurora A Primary Antibody for ICC, IF - ABIN151177 : Cremet, Descamps, Vérite, Martin, Prigent: Preparation and characterization of a human aurora-A kinase monoclonal antibody. in Molecular and cellular biochemistry 2003 (PubMed)
    Show all 2 references for ABIN151177

  4. Human Polyclonal Aurora A Primary Antibody for WB - ABIN374071 : Zhou, Kuang, Zhong, Kuo, Gray, Sahin, Brinkley, Sen: Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. in Nature genetics 1998 (PubMed)

  5. Human Polyclonal Aurora A Primary Antibody for EIA, IHC (p) - ABIN360272 : Kimura, Kotani, Hattori, Sumi, Yoshioka, Todokoro, Okano: Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. in The Journal of biological chemistry 1997 (PubMed)

  6. Cow (Bovine) Polyclonal Aurora A Primary Antibody for IHC, WB - ABIN2777171 : Ye, Yang, Grossman, Dinney, Wu, Gu: Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. in Cancer 2008 (PubMed)

更多抗Aurora A的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Aurora Kinase A (AURKA) interaction partners

  1. Disrupting the spindle assembly checkpoint in the aurA mutant does not prevent neuroblast amplification, tumor formation or chromosome segregation.

  2. Aurora A kinase activity contributes to phosphorylation of kinetochore substrates near poles and its inhibition results in chromosome misalignment and an increased incidence of erroneous kinetochore-MT attachments.

  3. AurA and aPKC exert the spatiotemporal control of Lgl distribution to achieve unique cell polarity roles in distinct cell types.

  4. Aurora A and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  5. Drosophila melanogaster aurora A phosphorylates the dynactin (显示 DCTN1 抗体) subunit p150(glued (显示 DCTN1 抗体)) on sites required for its association with the mitotic spindle.

  6. One of the functions of Aurora A kinase is to direct centrosomal organization such that D-TACC complexed to the MSPS/XMAP215 (显示 CKAP5 抗体) microtubule-associated protein (显示 FAM82A2 抗体) may be recruited, and thus modulate the behavior of astral microtubules.

  7. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.

  8. Deletion mapping identifies a central domain of Aurora-A as essential for its centrosomal localization that is augmented by both the amino and the carboxyl terminal ends of the protein.

  9. Results suggest that Aurora-A regulates centrosome assembly by controlling centrosomin's (CNN) ability to target and/or anchor gamma-tubulin (显示 TUBG1 抗体) to the centrosome and to organize microtubule-nucleating sites via interaction with CNN.

  10. Aurora-A is essential for many crucial events during mitosis and phosphorylation of a series of substrates by Aurora-A at different stages of mitosis may promote diverse critical events in mitosis to maintain chromosome integrity in cells

Zebrafish Aurora Kinase A (AURKA) interaction partners

  1. Zebrafish Aurora-A is critically required for embryonic proliferation during development.

Human Aurora Kinase A (AURKA) interaction partners

  1. Our study negatively correlates expression of PHLDA1 (显示 PHLDA1 抗体) and Aurora A in IMR-32 cells and sheds new light on functions of PHLDA1 (显示 PHLDA1 抗体) in the neuroblastoma (显示 ARHGEF16 抗体) tumor cells, suggesting its role as a pro-apoptotic protein

  2. Results confirmed that AURKA is highly expressed in lung adenocarcinoma tissues and human lung adenocarcinoma cell lines. Its knockdown in human lung adenocarcinoma could inhibit cell growth and proliferation in vitro providing evidence for its important roles in the proliferation of human lung adenocarcinoma cells.

  3. This study concludes that the helical region of TPX2 (显示 TPX2 抗体) folds upon binding Aurora-A, and that stabilization of this helix does not compromise Aurora-A activation.

  4. AURKA may induce EMT (显示 ITK 抗体) to promote metastasis via activation of the FAK (显示 PTK2 抗体)/PI3K (显示 PIK3CA 抗体) pathway in LSCC.

  5. a resorcinol derivative, 5-methyl-4-(2-thiazolylazo) resorcinol (PTK66), a dual inhibitor of Aurora A and Aurora B (显示 AURKB 抗体) kinases. PTK66 is a surface binding non-ATP analogue inhibitor that shows a mixed pattern of inhibition against both of Aurora A and B kinases

  6. Aurora-A overexpression upregulates MMP-2 (显示 MMP2 抗体) expression through activating AKT (显示 AKT1 抗体)/NF-kappaB (显示 NFKB1 抗体) signaling pathway in esophageal squamous cell carcinoma cells. The level of Aurora-A expression was also positively correlated with the invasion capability of the cells.

  7. several hits in 3-5 nm range of activity against Aurora A kinase with rather good selectivity and ADME properties were obtained.

  8. overexpression of PAK1 (显示 PAK1 抗体), NEK6 (显示 NEK6 抗体), AURKA, and AURKB (显示 AURKB 抗体) genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

  9. The reported findings suggest AURKA as a new tool to predict the clinical behavior of HGSOC. Particularly, these results suggest that AURKA may have a role both as predictor of platinum-resistance and prognostic factor.

  10. Upregulation of STK15 is associated with esophageal squamous cell carcinomas.

Mouse (Murine) Aurora Kinase A (AURKA) interaction partners

  1. Data show that aurora-A kinase (AURKA) supports effective spindle formation in zygote.

  2. observations revealed that the alteration of PKB-GSK-3beta axis, Plk-1, and Aurora kinase-A expressions in HSPC compartment due to DNA damage response was associated with the proliferative impairment and apoptosis during aplastic anemia.

  3. Augmented expression of Aurora kinase-A and Polo-like kinase-1 (显示 PLK1 抗体) at the lactogenic switch likely mediates the formation of binucleated cells.

  4. Aurora A inhibition causes delocalized clustering of Lck (显示 LCK 抗体) at the immunological synapses and decreases its phosphorylation levels thus indicating Aurora A is required for maintaining Lck (显示 LCK 抗体) active during T-cell activation.

  5. Ndel1 (显示 NDEL1 抗体) acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.

  6. The Aurora kinase A and c-Myc (显示 MYC 抗体) expression and histone H3 (显示 HIST3H3 抗体) phosphorylation level were comparatively higher in the cranial tumor than the caudal (显示 CAD 抗体).

  7. aurora kinase A (AURKA) represents a new therapeutic target in primary myelofibrosis.

  8. A novel function was identified for Aurora-A in controlling the polarization of macrophages and inflammation.

  9. Wdr62 (显示 WDR62 抗体) interacts with Aurora A to control mitotic progression, and loss of these interactions leads to mitotic delay and cell death of NPCs, which could be a potential cause of human microcephaly.

  10. Reduced levels of Aurora A protein immediately post-thaw may be associated with the impaired oocyte maturation manifested by the delayed progression through meiosis

Cow (Bovine) Aurora Kinase A (AURKA) interaction partners

  1. Aurora A was the most abundant form in oocytes, both at mRNA and protein levels, in bovine oocytes during meiotic maturation.

Pig (Porcine) Aurora Kinase A (AURKA) interaction partners

  1. Aurora kinase A is unlikely to be involved in CPEB1 (显示 CPEB1 抗体) activating phosphorylation and cyclin B1 (显示 CCNB1 抗体) mRNA polyadenylation during meiotic maturation of porcine oocytes.

  2. Aurora-A may be a multifunctional kinase that plays pivotal regulatory roles in microtubule assembly during porcine oocyte meiotic maturation, fertilization and early embryonic mitosis

  3. Aurora A stimulates the protein synthesis and promotes the meiotic resumption.

Xenopus laevis Aurora Kinase A (AURKA) interaction partners

  1. These results suggest a novel relationship between AurA and protein phosphatases during progression throughout the early embryonic cell cycle and shed new light on potential defects caused by AurA overexpression.

  2. MCAK (显示 KIF2C 抗体) colocalized with NuMA (显示 NUMA1 抗体) and XMAP215 (显示 CKAP5 抗体) at the center of Ran asters where its activity is regulated by Aurora A-dependent phosphorylation of S196, which contributes to proper pole focusing

  3. Plx1 (显示 PLK1 抗体) promotes activation of Aurora A, most likely through TPX2.

  4. Aurora-A kinase is required for astral microtubule polymerization and spindle microtubule flux during chromosome segregation.

  5. Data show that Aurora A is a key regulator of microtubule assembly during M phase and therefore of bipolar spindle formation.

  6. binding and elution properties of both the phosphopeptides and unphosphorylated peptides of His6-Aurora A

  7. Results suggest that phosphorylation of maskin (显示 TACC3 抗体) by Aurora-A prevents meiosis II proteins from being produced during meiosis I.

  8. The N-terminal non-catalytic domain of Aurora-A can localize to the centrosome in Xenopus egg extracts, while GFP fusions of either the N-terminal or catalytic domains are targeted to the centrosome in Xenopus XL2 cells.

  9. Here we identify G205 in Xenopus Aurora A as a key determinant of both intrinsic activity and regulation by TPX2

  10. The catalytic domain alone of Aurora-A is sufficient to restore spindle bipolarity; additional N-terminal sequences function in mitotic timing.

Aurora A (AURKA) 抗原简介

Antigen Summary

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Aurora A (AURKA)

  • aurora (aur) 抗体
  • aurora kinase A (aurka) 抗体
  • hypothetical protein (Aurora-A) 抗体
  • aurora kinase A (AURKA) 抗体
  • aurora kinase A (Aurka) 抗体
  • 87A7-9/2 抗体
  • AIK 抗体
  • AIRK1 抗体
  • ARK-1 抗体
  • Ark1 抗体
  • AU019385 抗体
  • aur-a 抗体
  • AURA 抗体
  • aurka 抗体
  • aurka-a 抗体
  • Aurora-A 抗体
  • AURORA2 抗体
  • AW539821 抗体
  • Ayk1 抗体
  • BTAK 抗体
  • CG3068 抗体
  • ck10 抗体
  • ck[10] 抗体
  • Dmel\\CG3068 抗体
  • Eg2 抗体
  • IAK 抗体
  • IAK1 抗体
  • l(3)87Ac 抗体
  • l(3)ck10 抗体
  • pEg2 抗体
  • PPP1R47 抗体
  • Stk6 抗体
  • STK7 抗体
  • STK15 抗体
  • wu:fb37c10 抗体
  • wu:fc02c02 抗体
  • zgc:100912 抗体

Protein level used designations for anti-Aurora Kinase A (AURKA) 抗体

A-type aurora kinase , AuroraA , CG3068-PA , aur-PA , aurora A , aurora A kinase , aurora kinase , aurora-A , early-A , fruhe2 , Aurora A , hypothetical protein , aurora kinase A , fb37c10 , fc02c02 , serine/threonine-protein kinase 6 , serine/threonine protein kinase 6 , aurora A kinase protein , serine/threonine-protein kinase 6-like , ARK-1 , Aurora-A kinase , IPL1-related kinase , aurora 2 , aurora-related kinase 1 , aurora/IPL1-like kinase , aurora/IPL1-related kinase 1 , breast tumor-amplified kinase , breast-tumor-amplified kinase , hARK1 , protein phosphatase 1, regulatory subunit 47 , serine/threonine kinase 6 , serine/threonine protein kinase 15 , serine/threonine-protein kinase 15 , serine/threonine-protein kinase aurora-A , aurora family kinase 1 , ipl1- and aurora-related kinase 1 , serine/threonine-protein kinase Ayk1 , ratAurA , Aurora-A , Serine/threonine-protein kinase 6 , aurora kinase A-A , p46Eg265 , pEg2 , serine/threonine-protein kinase 6-A , serine/threonine-protein kinase Eg2 , serine/threonine-protein kinase Eg2-A

GENE ID SPECIES
41446 Drosophila melanogaster
549324 Xenopus (Silurana) tropicalis
7200473 Phaeodactylum tricornutum CCAP 1055/1
428167 Gallus gallus
445246 Danio rerio
469980 Pan troglodytes
698190 Macaca mulatta
100216431 Ovis aries
100303586 Saccoglossus kowalevskii
100398107 Callithrix jacchus
100459866 Pongo abelii
100469600 Ailuropoda melanoleuca
6790 Homo sapiens
20878 Mus musculus
261730 Rattus norvegicus
504437 Bos taurus
485940 Canis lupus familiaris
574063 Sus scrofa
397925 Xenopus laevis
anti-Aurora A (AURKA) 抗体 精选生产商
您还需要查找其他产品吗?