PARP1 (PARP1) ELISA试剂盒产品概述

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Poly (ADP-Ribose) Polymerase 1 ELISA试剂盒 (PARP1)
在www.antibodies-online.cn可供39 Poly (ADP-Ribose) Polymerase 1 (PARP1) ELISA试剂盒的12不同的供货商。 再加上,我们可以发PARP1 抗体 (424)PARP1 蛋白 (31)和数多这个蛋白质的别的产品。 总共522 PARP1产品已列进来了。
别名:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1
list all ELISA KIts 基因 基因ID UniProt
PARP1 142 P09874
PARP1 25591 P27008
PARP1 11545  

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适于 PARP1 相互作用对的更多 ELISA 试剂盒

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The results demonstrate that PARylation process in Drosophila is tightly regulated in the context of strands-breaks repair; PARP is essential during the maintenance of DNA integrity, but dispensable in the DNA repair process.

  2. A mutation of Parp also increases NAD+ levels; although, this was only observed in parkin (显示 PARK2 ELISA试剂盒) mutant flies and not in the heterozygous Parp mutants, possibly owing to an increased PARP activity in the parkin (显示 PARK2 ELISA试剂盒) mutants.

  3. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (显示 H2AFV ELISA试剂盒) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  4. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  5. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  6. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  7. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  8. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  9. PARP-e autoregulates Parp transcription

  10. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The NF90 (显示 MMP4 ELISA试剂盒) regulates PARP1 mRNA stability in hepatocellular carcinoma cells, and NF90 (显示 MMP4 ELISA试剂盒) is a potential target to inhibit PARP1 activity.

  2. In response to UV irradiation, DICER (显示 DICER1 ELISA试剂盒) is recruited to chromatin in a ZRF1 (显示 DNAJC2 ELISA试剂盒)-mediated manner. The H2A-ubiquitin binding protein ZRF1 (显示 DNAJC2 ELISA试剂盒) and DICER (显示 DICER1 ELISA试剂盒) together impact on the chromatin conformation via PARP1.

  3. This paper summarises the most significant current literature on the involvement of PARP-1 in gastrointestinal cancer, focusing in particular on its role in the development and occurrence of tumours, providing information about clinical trials and exploring therapeutic possibilities. [review]

  4. PARP-1 stabilizes Sox2 (显示 SOX2 ELISA试剂盒) binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 (显示 SOX2 ELISA试剂盒) pioneer activity at intractable genomic loci.

  5. PARP1 can modulate the tumor-suppressing function of HIPK2 (显示 HIPK2 ELISA试剂盒) by regulating the protein stability of HIPK2 (显示 HIPK2 ELISA试剂盒).

  6. HBx increased signs of DNA damage such as accumulation of 8-hydroxy-2'-deoxyguanosine and comet formation, which were reversed by overexpression of PARP1 and/or Sirt6 (显示 SIRT6 ELISA试剂盒)..physical interaction of HBx and PARP1 accelerates DNA damage by inhibiting recruitment of the DNA repair complex to the damaged DNA sites, which may lead to the onset of hepatocarcinogenesis

  7. these findings provide a foundation for the potential use of PARP1 inhibitors as a new treatment option for lung adenocarcinoma patients with elevated PARP1 expression.

  8. Elevated PARP (显示 COL11A2 ELISA试剂盒) expression correlated with worse prognosis in early stage breast cancer. [meta-analysis]

  9. study demonstrates that the individual and combined expression patterns of the DDR (显示 DDR1 ELISA试剂盒) molecules PARP1, gammaH2AX (显示 H2AFX ELISA试剂盒), BRCA1, and BRCA2 (显示 BRCA2 ELISA试剂盒) could be predictive of the prognosis of STS (显示 STS ELISA试剂盒) patients and suggests that controlling the activity of these DDR (显示 DDR1 ELISA试剂盒) molecules could be employed in new therapeutic stratagems for the treatment of STS (显示 STS ELISA试剂盒)

  10. PARP1/2 inhibitor simmiparib causes growth inhibition in cancer cell- or tissue-derived xenografts in nude mice.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. no difference was found in the level of SBDP145 between muscles, while SBDP120 and PARP-1 cleavage products were not detected

  2. ADPRT Val762Ala and APE1 (显示 APEX1 ELISA试剂盒) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  3. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  4. FGF2 (显示 FGF2 ELISA试剂盒) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (显示 MAPK1 ELISA试剂盒))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The findings suggest that PARP1 inhibition protects against long-term ethanol-induced liver injury, as indicated by limited hepatocytes steatosis, apoptosis, inflammation levels, and neutrophil infiltration, mainly by limiting KC activation during the initiation of ALD.

  2. PARP-1 knockout resulted in lowered arginase II (显示 ARG2 ELISA试剂盒) expression in macrophages and aortic endothelial cells.

  3. PARP-1 stabilizes Sox2 (显示 SOX2 ELISA试剂盒) binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 (显示 SOX2 ELISA试剂盒) pioneer activity at intractable genomic loci.

  4. Delayed healing in ischemic and diabetic wounds is caused by PARP hyperactivity, and PARP inhibition significantly enhanced ischemic and diabetic wound healing by promoting angiogenesis.

  5. The findings highlight specific non-overlapping functions of PARP1 and PARP2 (显示 PARP2 ELISA试剂盒) at H2AX (显示 H2AFX ELISA试剂盒)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 in nonhomologous end-joining-deficient cells.

  6. data establish the importance of XRCC1 (显示 XRCC1 ELISA试剂盒) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  7. this study shows that PARP-1 inhibition plays role in puerarin-mediated protection from liver fibrosis

  8. might be involved in streptomycin ototoxicity by regulating AIF (显示 AIFM1 ELISA试剂盒) translocation in cochlear hair cells

  9. Nonionizing radiofrequency exposure is capable of inducing PARP-1.

  10. our data suggest that Parp1 is involved in the plastic remodeling of chromatin structure after NT by supporting DNA repair and specific histone code modifications.

PARP1 抗原简介

Antigen Summary

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (PARP1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (Parp1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (parp1) Elisa Kit
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) Elisa Kit
  • poly ADP-ribose polymerase (Parp) Elisa Kit
  • 5830444G22Rik Elisa Kit
  • Adprp Elisa Kit
  • Adprt Elisa Kit
  • ADPRT 1 Elisa Kit
  • Adprt1 Elisa Kit
  • AI893648 Elisa Kit
  • ARTD1 Elisa Kit
  • BEST:LD21673 Elisa Kit
  • C80510 Elisa Kit
  • CG17685 Elisa Kit
  • CG17696 Elisa Kit
  • CG17718 Elisa Kit
  • CG40411 Elisa Kit
  • D.PARP Elisa Kit
  • Dm.pARTa Elisa Kit
  • Dmel\\CG40411 Elisa Kit
  • dPARP Elisa Kit
  • LD21673.3prime Elisa Kit
  • padprt-1 Elisa Kit
  • parp Elisa Kit
  • parp-1 Elisa Kit
  • PARP1 Elisa Kit
  • ppol Elisa Kit
  • sPARP-1 Elisa Kit

Protein level used designations for PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPECIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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