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anti-Caspase 4 (CASP4) 抗体产品概述

Full name:
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase 抗体 (CASP4)
在www.antibodies-online.cn可供260 Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) 抗体的29不同的供货商。 再加上,我们可以发Caspase 4 试剂盒 (54)Caspase 4 蛋白 (24)和数多这个蛋白质的别的产品。 总共354 Caspase 4产品已列进来了。
别名:
CASP1, CASP4, Casp11, CASP13, Caspl, ICE(rel)II, ICEREL-II, ICH-2, ich-3, Mih1/TX, TX
列出全部抗体 基因 基因ID UniProt
CASP4 837 P49662
CASP4 12363 P70343
CASP4 114555  

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抗Human Caspase 4 抗体:

抗Mouse (Murine) Caspase 4 抗体:

抗Rat (Rattus) Caspase 4 抗体:

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引用最多的anti-Caspase 4 抗体

  1. Human Monoclonal Caspase 4 Primary Antibody for ELISA, ICC - ABIN265762 : Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. in The Biochemical journal 2012 (PubMed)
    Show all 21 references for ABIN265762

  2. Human Polyclonal Caspase 4 Primary Antibody for EIA, IF - ABIN499561 : Kamens, Paskind, Hugunin, Talanian, Allen, Banach, Bump, Hackett, Johnston, Li: Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. in The Journal of biological chemistry 1995 (PubMed)
    Show all 4 references for ABIN499561

  3. Human Polyclonal Caspase 4 Primary Antibody for EIA, IHC (p) - ABIN499563 : Gracie, Robertson, McInnes: Interleukin-18. in Journal of leukocyte biology 2003 (PubMed)
    Show all 4 references for ABIN499563

  4. Human Monoclonal Caspase 4 Primary Antibody for WB - ABIN967534 : Faucheu, Diu, Chan, Blanchet, Miossec, Hervé, Collard-Dutilleul, Gu, Aldape, Lippke: A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. in The EMBO journal 1995 (PubMed)
    Show all 2 references for ABIN967534

  5. Human Polyclonal Caspase 4 Primary Antibody for ELISA, WB - ABIN185284 : Munday, Vaillancourt, Ali, Casano, Miller, Molineaux, Yamin, Yu, Nicholson: Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. in The Journal of biological chemistry 1995 (PubMed)

  6. Human Monoclonal Caspase 4 Primary Antibody for WB - ABIN223055 : Kim, Zhang, Hitomi, Lee, Mukherjee: Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. in Human molecular genetics 2006 (PubMed)

  7. Mouse (Murine) Polyclonal Caspase 4 Primary Antibody for WB - ABIN222879 : Huang, Xie, Qiao, Qiu, Huang, Li, Chen, Liu, Wang, Lin, Wang: Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. in Toxicological sciences : an official journal of the Society of Toxicology 2015 (PubMed)

更多抗Caspase 4的相互作用对抗体

Human Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. We propose that microglial caspase-4 expression contributes to the cognitive impairments in Alzheimer's disease (AD), and that further study of caspase-4 will enhance our understanding of AD pathogenesis and may lead to novel therapeutic targets in AD.

  2. this study shows that activation of caspase-4 is mediated by interactions with endotoxin-rich membrane interfaces rather than by endotoxin monomers

  3. Specific activation of caspase-3 (显示 CASP3 抗体) and caspase-4 was found in proplatelets. Consistent with previous observations of caspase-4 autoactivation in response to endoplasmic reticulum (ER) stress, several ER stress marker proteins were expressed during proplatelet formation.

  4. apoptosis is induced by rhein traditional Chinese medicine via induction of endoplasmic reticulum stress, caspase-4 and intracellular calcium in primary human hepatic HL-7702 cells

  5. Caspase-4 and caspase-5 (显示 CASP5 抗体) mediate IL-1alpha and IL-1beta (显示 IL1B 抗体) release from human monocytes after lipopolysaccharides stimulation.

  6. both caspase-4 and caspase-5 (显示 CASP5 抗体) are functionally important for appropriate responses to intracellular Gram-negative bacteria.

  7. caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 (显示 NLRP3 抗体) inflammasome activation to drive IL-1beta (显示 IL1B 抗体) maturation.

  8. This study reveled that CASP4 having a central role in the bipolar disease and schizophrenia manifestation.

  9. NF-kappaB (显示 NFKB1 抗体) can mediate Fas (显示 FAS 抗体)-induced apoptosis through caspase-4 protease

  10. implicate caspase-4 as a critical regulator of noncanonical inflammasome activation that initiates defense against bacterial pathogens in primary macrophages

Mouse (Murine) Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Caspase-11 targets cofilin (显示 CFL1 抗体) via the RhoA GTPase, whereas caspase-1 (显示 CASP1 抗体) engages the Slingshot phosphatase

  2. Hyperactive dendritic cells induce potent adaptive immune responses and are elicited by caspase-11, an enzyme that binds oxidized phospholipids and bacterial lipopolysaccharide.

  3. Caspase-1 (显示 CASP1 抗体)-activated IL-18 (显示 IL18 抗体) induces IFN-gamma (显示 IFNG 抗体) to prime caspase-11 and rapidly clear Burkholderia thailandensis infection.

  4. These results argue that caspase-1 (显示 CASP1 抗体), -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  5. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  6. But not in Casp11(-/-), Panx1 (显示 PANX1 抗体)(-/-), or P2x7 (显示 P2RX7 抗体)(-/-) mice.

  7. active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3 (显示 NLRP3 抗体).

  8. Data show that caspase-1 (显示 CASP1 抗体) but not caspase-11 was essential for the functional activities of the NLRC4 (显示 NLRC4 抗体) inflammasome.

  9. Data indicate that genetic ablation of caspase-1 (显示 CASP1 抗体) and -11 from cpdm (显示 SHARPIN 抗体) mice significantly reduced skin inflammation in sharpin (显示 SHARPIN 抗体)-deficient mice.

  10. These results suggest a role for other caspase-11 effector mechanisms such as pyroptosis in protection against intestinal inflammation.

Caspase 4 (CASP4) 抗原简介

Antigen Summary

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 4 (CASP4)

  • caspase 4 (CASP4) 抗体
  • caspase 11 (LOC100101589) 抗体
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) 抗体
  • caspase 4, apoptosis-related cysteine peptidase (Casp4) 抗体
  • caspase-4-like (LOC100359184) 抗体
  • CASP1 抗体
  • CASP4 抗体
  • Casp11 抗体
  • CASP13 抗体
  • Caspl 抗体
  • ICE(rel)II 抗体
  • ICEREL-II 抗体
  • ICH-2 抗体
  • ich-3 抗体
  • Mih1/TX 抗体
  • TX 抗体

Protein level used designations for CASP4

caspase 4 , CASP-4 , ICE(rel)-II , apoptotic cysteine protease Mih1/TX , caspase 4, apoptosis-related cysteine protease , caspase-4 , protease ICH-2 , protease TX , CASP-11 , caspase 11, apoptosis-related cysteine peptidase , caspase 11, apoptosis-related cysteine protease , caspase-11 short form splicing , protease ICH-3 , caspase 11 , CASP-1 , ICE , IL-1 beta-converting enzyme , IL-1BC , caspase-1 , caspase-1/caspase-4 hybrid , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , CASP-13 , ERICE , caspase 13 , caspase-13 , evolutionary related interleukin-1-beta-converting enzyme

GENE ID SPECIES
704864 Macaca mulatta
100101589 Oryctolagus cuniculus
837 Homo sapiens
12363 Mus musculus
114555 Rattus norvegicus
403724 Canis lupus familiaris
338039 Bos taurus
100359184 Oryctolagus cuniculus
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