Caspase 2 (CASP2) ELISA试剂盒产品概述

Full name:
Caspase 2, Apoptosis-Related Cysteine Peptidase ELISA试剂盒 (CASP2)
在www.antibodies-online.cn可供29 Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) ELISA试剂盒的13不同的供货商。 再加上,我们可以发Caspase 2 抗体 (220)Caspase 2 蛋白 (25)和数多这个蛋白质的别的产品。 总共283 Caspase 2产品已列进来了。
CASP-2, Caspase-2, ICH-1, ICH-1L/1S, ICH1, ICH1L1S, NEDD-2, NEDD2, PPP1R57, xCaspase-2

引用最多的Caspase 2 ELISA试剂盒

  1. ABIN411819 : Ark, Ozdemir, Polat: Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2. in Apoptosis : an international journal on programmed cell death 2010 (PubMed)
    Show all 4 references for 411819

  2. ABIN412025 : Espín, Roca, Candel, Sepulcre, González-Rosa, Alcaraz-Pérez, Meseguer, Cayuela, Mercader, Mulero: TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. in Disease models & mechanisms 2013 (PubMed)
    Show all 4 references for 412025

  3. ABIN411815 : Sapet, Simoncini, Loriod, Puthier, Sampol, Nguyen, Dignat-George, Anfosso: Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2. in Blood 2006 (PubMed)
    Show all 3 references for 411815

适于 Caspase 2 相互作用对的更多 ELISA 试剂盒

Xenopus laevis Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) interaction partners

  1. caspase-2 has a role as an initiator caspase (显示 CASP3 ELISA试剂盒) in lipoapoptosis

  2. tail regression at metamorphosis implicates an apoptotic pathway inducible by T(3) hormone in an organ autonomous manner and involving the cell death executioners BH3 interacting domain death agonist (显示 BID ELISA试剂盒) and Caspases-2 and -8

  3. Caspase-2 phosphorylated at S135 binds 14-3-3zeta (显示 YWHAZ ELISA试剂盒), thus preventing C2 dephosphorylation.

  4. The data demonstrate that cell death is prevented during mitosis through the inhibitory phosphorylation of caspase-2 and suggest that under conditions of mitotic arrest, cdk1 (显示 CDK1 ELISA试剂盒)-cyclin B1 (显示 CCNB1 ELISA试剂盒) activity must be overcome for apoptosis to occur.

Mouse (Murine) Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) interaction partners

  1. We further generated Casp2(C320S) mutant mice to demonstrate that caspase-2 catalytic activity is essential for its function in limiting aneuploidy. Our results provide direct evidence that the apoptotic activity of caspase-2 is necessary for deleting cells with mitotic aberrations to limit aneuploidy

  2. These results provide the first evidence of caspase-2 in regulating haematopoietic stem cell and progenitor differentiation, as well as aneuploidy, in vivo.

  3. Study describes a novel pathological process in which caspase-2 cleavage of tau at Asp314 impairs cognitive and synaptic function in animal and cellular models of tauopathies by promoting the missorting of tau to dendritic spines.

  4. Caspase-2 deficiency protected mice from diet-induced obesity, metabolic syndrome and nonalcoholic fatty liver disease.

  5. The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein (显示 HOMER1 ELISA试剂盒) Raidd (显示 CRADD ELISA试剂盒)

  6. Data show that indoles can effectively suppress acute hepatic inflammation caused by staphylococcal enterotoxin B (SEB) maybe mediated by decreased expression of miR-31 and caspase-2-dependent apoptosis in T cells.

  7. Data indicate that the nucleotide-binding domain and leucine-rich repeat containing (显示 NLRX1 ELISA试剂盒) (NLRP3 (显示 NLRP3 ELISA试剂盒))-caspase-2 axis drives general endoplasmic reticulum (ER) stress-induced inflammasome activation.

  8. these studies elucidate a Caspase-2-p53 (显示 TP53 ELISA试剂盒) signaling network that impacts lung tumorigenesis and chemotherapy response in vivo.

  9. data strongly suggest that caspase-2 deficiency leads to increased cellular stress largely because these mice fail to respond to oxidative stress by upregulating their antioxidant defense mechanism

  10. These results demonstrate an important role for caspase-2 in regulating proteome and metabolome remodelling during ageing.

Human Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) interaction partners

  1. NPM1 (显示 NPM1 ELISA试剂盒)-dependent nucleolar PIDDosome is a key initiator of the caspase-2 activation cascade.

  2. Sensitization of colon carcinoma cells to radiation-induced cell death and DNA-damage by HuR (显示 ELAVL1 ELISA试剂盒) knockdown critically depends on caspase-2.

  3. BCL9L (显示 BCL9L ELISA试剂盒) dysfunction contributes to aneuploidy tolerance in both TP53 (显示 TP53 ELISA试剂盒)-WT and mutant cells by reducing basal caspase-2 levels and preventing cleavage of MDM2 (显示 MDM2 ELISA试剂盒) and BID (显示 BID ELISA试剂盒).

  4. CASP2 down-regulation had a reverse relationship with miR (显示 MLXIP ELISA试剂盒)-383 down-regulation in regulating epithelial ovarian cancer development.

  5. Results suggest that mutations at all three cleavage sites of caspase-2 protein neither affect the macromolecular core complex assembly, nor modify caspase-2 activity upon DNA damage. Consequently, caspase-2 activation occurs in the macromolecular complex without its dissociation.

  6. These findings indicate that miR (显示 MLXIP ELISA试剂盒)-125a-5p decreases after HOTAIR knockdown to promote cancer cell apoptosis by releasing caspase 2.

  7. these studies elucidate a Caspase-2-p53 (显示 TP53 ELISA试剂盒) signaling network that impacts lung tumorigenesis and chemotherapy response in vivo.

  8. We have also demonstrated that these correlations are tissue specific being reduced (CASP9 (显示 CASP9 ELISA试剂盒) and CASP10 (显示 CASP10 ELISA试剂盒)) or different (CASP2) in the liver

  9. the initiator caspase-2 is required for robust death of ovarian cancer cells induced by FASN (显示 FASN ELISA试剂盒) inhibitors

  10. HuR (显示 ELAVL1 ELISA试剂盒) sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by upregulating the translation of caspase-2.

Cow (Bovine) Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) interaction partners

  1. EtOH-induced mitochondria-mediated apoptosis is initiated by caspase-2 activation, which is regulated by CoQ10

  2. the capacity for blastocysts to undergo further development is related to degree of group II caspase (显示 CASP3 ELISA试剂盒) activity

Pig (Porcine) Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) interaction partners

  1. hypoxia/re-oxygenation injury in cultured proximal tubule cells induced apoptosis by activation of caspase-2, which is required for the mitochondrial translocation of Bax (显示 BAX ELISA试剂盒).

Caspase 2 (CASP2) 抗原简介

Antigen Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Caspase 2 (CASP2)

  • caspase-2-like (LOC100050611) Elisa Kit
  • caspase-2 (xCaspase-2) Elisa Kit
  • caspase-2 (CpipJ_CPIJ008254) Elisa Kit
  • caspase 2 (Casp2) Elisa Kit
  • caspase 2 (LOC100101590) Elisa Kit
  • caspase 2, apoptosis-related cysteine peptidase (CASP2) Elisa Kit
  • caspase 2, apoptosis-related cysteine peptidase (Casp2) Elisa Kit
  • caspase-2-like (LOC100521118) Elisa Kit
  • CASP-2 Elisa Kit
  • Caspase-2 Elisa Kit
  • ICH-1 Elisa Kit
  • ICH-1L/1S Elisa Kit
  • ICH1 Elisa Kit
  • ICH1L1S Elisa Kit
  • NEDD-2 Elisa Kit
  • NEDD2 Elisa Kit
  • PPP1R57 Elisa Kit
  • xCaspase-2 Elisa Kit

Protein level used designations for CASP2

caspase-2 , CASP-2 , ICH-1 protease , protease ICH-1 , NEDD-2 , neural precursor cell expressed developmentally down-regulated protein 2 , protein phosphatase 1, regulatory subunit 57 , caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) , ICH1 protease , caspase 2, apoptosis-related cysteine protease , cysteine protease caspase-2

100050611 Equus caballus
397817 Xenopus laevis
6040179 Culex quinquefasciatus
64314 Rattus norvegicus
12366 Mus musculus
100101590 Oryctolagus cuniculus
835 Homo sapiens
482737 Canis lupus familiaris
531419 Bos taurus
395857 Gallus gallus
100735399 Cavia porcellus
100521118 Sus scrofa
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