gamma 1 Adaptin 抗体 (AA 642-821)
(5 references)Quick Overview for gamma 1 Adaptin 抗体 (AA 642-821) (ABIN967934)
抗原
See all gamma 1 Adaptin (AP1G1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 642-821
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交叉反应
- 大鼠, 人, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Mouse Adaptin gamma aa. 642-821
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亚型
- IgG1
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anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 721-822) antibody
AP1G1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 592-686) antibodyAP1G1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibodyAP1G1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (C-Term) antibodyAP1G1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 574-623) antibodyAP1G1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 1-240) antibodyAP1G1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibodyKD Validated AP1G1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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说明
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Related Products: ABIN968539, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).
: "Role of LAMP-2 in lysosome biogenesis and autophagy." in: Molecular biology of the cell, Vol. 13, Issue 9, pp. 3355-68, (2002) (PubMed).
: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).
: "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics." in: The Journal of cell biology, Vol. 158, Issue 5, pp. 855-62, (2002) (PubMed).
: "Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2319-26, (1991) (PubMed).
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: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).
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- gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))
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别名
- Adaptin gamma
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背景
- Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins (gamma, alpha, delta, or epsilon and beta1, beta2, beta3, or beta4, respectively) that are noncovalently linked to one medium chain (µ1, µ2, µ3, or µ4) and one small chain ( sigma1, sigma2, sigma3, or sigma4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. Adaptin gamma shows more homology with Adaptin alpha than with Adaptin beta. The conserved regions between Adaptins gamma and alpha could be important for binding to other components of the AP-1 and AP-2 complexes, respectively.
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分子量
- 104 kDa
抗原
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