电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MYOD1 抗体

MYOD1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC (fro) 宿主: 小鼠 Monoclonal 5-8A unconjugated
产品编号 ABIN967403
发货至: 中国
  • 抗原 See all MYOD1 抗体
    MYOD1 (Myogenic Differentiation 1 (MYOD1))
    适用
    • 129
    • 86
    • 75
    • 26
    • 2
    人, 小鼠, 大鼠, 小鸡
    宿主
    • 88
    • 47
    • 1
    小鼠
    克隆类型
    • 76
    • 60
    单克隆
    标记
    • 75
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYOD1 antibody is un-conjugated
    应用范围
    • 73
    • 44
    • 44
    • 38
    • 22
    • 18
    • 17
    • 16
    • 13
    • 11
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    交叉反应
    人, 大鼠, 小鸡
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Recombinant Mouse MyoD
    克隆位点
    5-8A
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MYOD1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4° C.
  • Rawls, Valdez, Zhang, Richardson, Klein, Olson: "Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice." in: Development (Cambridge, England), Vol. 125, Issue 13, pp. 2349-58, (1998) (PubMed).

    Gredinger, Gerber, Tamir, Tapscott, Bengal: "Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10436-44, (1998) (PubMed).

    Dias, Dilling, Houghton: "The molecular basis of skeletal muscle differentiation." in: Seminars in diagnostic pathology, Vol. 11, Issue 1, pp. 3-14, (1994) (PubMed).

    Dias, Parham, Shapiro, Tapscott, Houghton: "Monoclonal antibodies to the myogenic regulatory protein MyoD1: epitope mapping and diagnostic utility." in: Cancer research, Vol. 52, Issue 23, pp. 6431-9, (1992) (PubMed).

    Davis, Weintraub, Lassar: "Expression of a single transfected cDNA converts fibroblasts to myoblasts." in: Cell, Vol. 51, Issue 6, pp. 987-1000, (1988) (PubMed).

  • 抗原
    MYOD1 (Myogenic Differentiation 1 (MYOD1))
    别名
    MyoD (MYOD1 产品)
    别名
    MYF3 antibody, MYOD antibody, PUM antibody, bHLHc1 antibody, MyoD antibody, XMyoD antibody, XtmyoD antibody, mf25 antibody, myf3 antibody, pum antibody, MUF3 antibody, AI503393 antibody, Myod-1 antibody, etID309723.25 antibody, myod antibody, wu:fb57a01 antibody, zgc:136744 antibody, MYOD1 antibody, myod1 antibody, mf1 antibody, myod1-a antibody, myod1-b antibody, myogenic differentiation 1 antibody, MYOD protein antibody, myogenic factor MyoD1 antibody, myogenic differentiation 1 S homeolog antibody, myogenic differentiation 1 L homeolog antibody, MYOD1 antibody, myod1 antibody, Myod1 antibody, myod antibody, myod1.S antibody, myod1.L antibody
    背景
    MyoD is a member of a family of myogenic basic helix-loop-helix (bHLH) transcription factors that includes Myf-5, myogenin, and MRF4 (also known as herculin or Myf-6). Members of this family, expressed exclusively in skeletal muscle, play a key role in myogenesis by activating muscle-specific genes in response to extracellular growth factors. Transfection of MyoD and other family members into non-muscle cells has been shown to either convert these cells to myogenic cells or to transcriptionally activate a set of otherwise unexpressed muscle-specific genes. Members of this family have distinct roles in muscle development, for example, MyoD and Myf-5 act early during myeloid development, whereas myogenin acts at a later point during myoblast differentiation. The expression and activity of MyoD has been shown to involve the mitogen-activated protein kinase (MAPK) cascade. This antibody is routinely tested by western blot analysis. The epitope for MoAb 5.8A has been mapped to amino acids 180-189nof mouse MyoD.
    分子量
    45/48 kDa
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
You are here:
客服