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SIRT6 抗体 (C-Term)

This anti-SIRT6 antibody is a 兔 多克隆 antibody detecting SIRT6 in IHC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN967032
发货至: 中国

Quick Overview for SIRT6 抗体 (C-Term) (ABIN967032)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

  • 94
  • 34
  • 19
  • 5
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  • 3
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  • 1
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宿主

  • 94
  • 14
  • 2

克隆类型

  • 88
  • 22
多克隆

标记

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  • 1
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This SIRT6 antibody is un-conjugated

应用范围

  • 90
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  • 14
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  • 9
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Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 12
    • 6
    • 6
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    • 1
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    C-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6)
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Kawahara, Michishita, Adler, Damian, Berber, Lin, McCord, Ongaigui, Boxer, Chang, Chua: "SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span." in: Cell, Vol. 136, Issue 1, pp. 62-74, (2009) (PubMed).

    Michishita, McCord, Berber, Kioi, Padilla-Nash, Damian, Cheung, Kusumoto, Kawahara, Barrett, Chang, Bohr, Ried, Gozani, Chua: "SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin." in: Nature, Vol. 452, Issue 7186, pp. 492-6, (2008) (PubMed).

    Kanfi, Shalman, Peshti, Pilosof, Gozlan, Pearson, Lerrer, Moazed, Marine, de Cabo, Cohen: "Regulation of SIRT6 protein levels by nutrient availability." in: FEBS letters, Vol. 582, Issue 5, pp. 543-8, (2008) (PubMed).

  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6) is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT6 (Mono-ADPribosyltransferase sirtuin-6) is included in class IV of the sirtuin family. SIRT6 (Mono-ADPribosyltransferase sirtuin-6) contains 1 deacetylase sirtuin-type domain.
    Synonyms: SIR2L6(SIR2-like protein 6)
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