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FES 抗体

FES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A11G5 unconjugated
产品编号 ABIN966135
发货至: 中国
  • 抗原 See all FES 抗体
    FES (Feline Sarcoma Oncogene (FES))
    适用
    • 38
    • 21
    • 14
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 35
    • 4
    • 1
    小鼠
    克隆类型
    • 37
    • 3
    单克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FES antibody is un-conjugated
    应用范围
    • 25
    • 11
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of FES expressed in E. Coli.
    克隆位点
    5A11G5
    亚型
    IgG1
    Top Product
    Discover our top product FES Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Vitenzon, Mironov, Petrushanskaya: "Functional electrostimulation of muscles as a method for restoring motor functions." in: Neuroscience and behavioral physiology, Vol. 35, Issue 7, pp. 709-14, (2006) (PubMed).

  • 抗原
    FES (Feline Sarcoma Oncogene (FES))
    别名
    FES (FES 产品)
    别名
    FPS antibody, RGD1564385 antibody, AI586313 antibody, BB137047 antibody, c-fes antibody, FES antibody, c-fps antibody, FES proto-oncogene, tyrosine kinase antibody, feline sarcoma oncogene antibody, FES antibody, Fes antibody, fes antibody
    背景
    FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosinespecific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
    Synonyms: FPS
    基因ID
    2242
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2
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