ATP6V1A 抗体 (AA 441-468)
Our Local Distributor
北京 101111
Quick Overview for ATP6V1A 抗体 (AA 441-468) (ABIN653735)
抗原
See all ATP6V1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 441-468
-
预测反应
- B, M, Pig
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This ATP6V1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-468 amino acids from the Central region of human ATP6V1A.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. IHC-P: 1:50~100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "Hypoxia inducible NOD2 interacts with 3-O-sulfogalactoceramide and regulates vesicular homeostasis." in: Biochimica et biophysica acta, Vol. 1830, Issue 11, pp. 5277-86, (2013) (PubMed).
-
-
- ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))
-
别名
- ATP6V1A
-
背景
- This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.
-
分子量
- 68304
-
基因ID
- 523
-
NCBI登录号
- NP_001681
-
UniProt
- P38606
-
途径
- Transition Metal Ion Homeostasis, Proton Transport, SARS-CoV-2 Protein Interactome
抗原
-