CPSF1 抗体 (Middle Region)
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北京 101111
Quick Overview for CPSF1 抗体 (Middle Region) (ABIN310073)
抗原
See all CPSF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GCYDMWTVIA PVRKEEEDNP KGEGTEQEPS TTPEADDDGR RHGFLILSRE
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预测反应
- Horse: 79%, Human: 100%, Rat: 77%
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产品特性
- This is a rabbit polyclonal antibody against CPSF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CPSF1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1443 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))
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别名
- CPSF1
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背景
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CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Alias Symbols: CPSF160, HSU37012, P/cl.18
Protein Interaction Partner: REL, RBBP6, UBC, STAU1, LGR4, WWOX, RPA3, RPA2, RPA1, EED, EZH2, NEDD4, TARDBP, ICK, CLK2, HDAC6, NPM1, IL7R, HMOX1, TUT1, FIP1L1, RNPC3, WDR33, CPSF2, MED8, CPSF3, GTF3C3, POLR2A, COPS6, CUL3, SIRT7, SMARCAD1, CSTF2T, PAPOLA, CSTF3, GLIS2, RRAGA, TBP, TA
Protein Size: 1443 -
分子量
- 161 kDa
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基因ID
- 29894
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NCBI登录号
- NM_013291, NP_037423
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UniProt
- Q10570
抗原
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