TCEB3 抗体 (C-Term)
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Quick Overview for TCEB3 抗体 (C-Term) (ABIN184283)
抗原
See all TCEB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AYDGPSTSSA HLAPVVSSTV SYDPRKPTVK KIAPMMAKTI KAFKNRFSRR
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交叉反应
- 犬, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Dog: 100%, Guinea Pig: 91%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against TCEB3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TCEB3
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应用备注
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WB Suggested Anti-TCEB3 Antibody Titration: 7.5 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 772 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
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别名
- TCEB3
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背景
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Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Alias Symbols: EloA, SIII, TCEB3A, SIII p110
Protein Interaction Partner: KRTAP10-3, CEP57L1, SPERT, FAM9B, KRT40, CEP70, GMCL1, HOMEZ, TRIM54, MID2, PLK4, JAKMIP2, PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, MDFI, UBC, RAD54B, MED26, ECT2, BARD1, CDK12, TCEB2, TCEB1, B
Protein Size: 772 -
分子量
- 87 kDa
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基因ID
- 6924
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NCBI登录号
- NM_003198, NP_003189
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UniProt
- Q14241
抗原
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