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VDAC1 抗体 (C-Term)

There are 3+ publications for this product available. The 兔多克隆 anti-VDAC1 antibody is suitable to detect VDAC1 in samples from 人, 大鼠, 小鼠, 兔, Cow, 犬, 绵羊, 马, 豚鼠和斑马鱼. It has been validated for WB 和 IHC.

Rabbit Anti-VDAC1 Antibody Paraffin Embedded Tissue: Human Liver Cellular Data: Hepatocytes Antibody Concentration: 4. (VDAC1 抗体 (C-Term))

IHC

Lanes: Lane 1: 50ug HeLa lysate Lane 2: 50ug 293T lysate Lane 3: 50ug K562 lysate Lane 4: 50ug MDA-MB-231 lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Gene Name: VDAC1 Submitted by: David Colecchia, Ph. (VDAC1 抗体 (C-Term))

4 images

(3 references)

产品编号 ABIN183134

发货至: 中国

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Quick Overview for VDAC1 抗体 (C-Term) (ABIN183134)

抗原

See all VDAC1 抗体

VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

适用

人, 大鼠, 小鼠, 兔, Cow, 犬, 绵羊, 马, 豚鼠, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This VDAC1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product VDAC1 Primary Antibody

抗原表位
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15

6

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4

2

2

2

2

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2

2

1

1

1

1

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1

1

1
C-Term

序列

SAKVNNSSLI GLGYTQTLKP GIKLTLSALL DGKNVNAGGH KLGLGLEFQA

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

产品特性

This is a rabbit polyclonal antibody against VDAC1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human VDAC1
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-30), (N-Term) antibody
VDAC1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19920 unconjugated

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 154-181), (Middle Region) antibody
VDAC1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 488)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 Atto 488

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 390)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 Atto 390

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Biotin)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 Biotin

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (APC)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 APC

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PerCP)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 PerCP

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PE)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 PE

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 594)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 Atto 594

anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (FITC)
VDAC1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S152B-23 FITC

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 283 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Rousset, Nguyen, Grange, Morel, Lardy: "Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes." in: PLoS ONE, Vol. 8, Issue 6, pp. e66478, (2013) (PubMed).

Arduíno, Esteves, Cortes, Silva, Patel, Grazina, Swerdlow, Oliveira, Cardoso: "Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic." in: Human molecular genetics, Vol. 21, Issue 21, pp. 4680-702, (2012) (PubMed).

Chen, Martin, Maya-Mendoza, Tang, Lovri?, Sims, Jackson: "Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins." in: Journal of proteome research, Vol. 8, Issue 11, pp. 5196-211, (2009) (PubMed).
抗原

VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

别名

VDAC1

背景

The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
Alias Symbols: PORIN, VDAC-1
Protein Interaction Partner: UBC, KLHL40, SPRTN, MDM2, ADRB2, ASB14, ASB17, PARK2, BAG3, env, VCAM1, HK1, ATF2, FMNL1, TUBA1B, MDC1, CAV1, Htt, SFXN3, SUGP1, UBAP2, UFM1, ACAD9, MGAT4B, ACAA2, ZMPSTE24, VAPA, ALDH5A1, SF1, VDAC3, VDAC2, UBA52, TIAL1, FLOT2, CDK2, SIRT7, SUMO4, MAPK3,
Protein Size: 283

分子量

31 kDa

基因ID

7416

NCBI登录号

NM_003374, NP_003365

UniProt

Q5FVE7