电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KRT8 抗体

KRT8 适用: 人, 大鼠, 小鼠, Hamster WB, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal Ks8-7 unconjugated
产品编号 ABIN112171
发货至: 中国
  • 抗原 See all KRT8 抗体
    KRT8 (Keratin 8 (KRT8))
    适用
    • 247
    • 80
    • 75
    • 32
    • 32
    • 30
    • 30
    • 16
    • 14
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Hamster
    宿主
    • 132
    • 124
    • 2
    • 1
    小鼠
    克隆类型
    • 129
    • 128
    单克隆
    标记
    • 137
    • 23
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    This KRT8 antibody is un-conjugated
    应用范围
    • 163
    • 96
    • 89
    • 83
    • 67
    • 49
    • 41
    • 40
    • 32
    • 29
    • 22
    • 18
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Ks 8.7 represents an excellent marker to discriminate simple epithelia from those of different origin. Polypetide Reacting: Mr 52500 polypeptide (keratin K8, formerly also designated cytokeratin 8) of human epithelia. Tumors Specifically Detected: All adeno-CA tested, undifferentiated CA, cervix CA, hepatocellular CA. Tested Reactivities on cultured cell lines: MCF-7, RT 112, PLC.
    纯化方法
    Protein A affinity chromatography
    免疫原
    Cytoskeletal proteins from cultured HeLa cells
    克隆位点
    Ks8-7
    亚型
    IgG1
    Top Product
    Discover our top product KRT8 Primary Antibody
  • 应用备注
    Western blot. Immunocytology. Immunohistochemistry (1: 10) on frozen tissues and paraffin-embedded sections aftermicrowave treatment. Incubation time: 1 h at RT.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in 1 mL distilled water.
    缓冲液
    Final solution contains 0.09 % Sodium Azide and 0.5 % BSA in PBS buffer, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    KRT8 (Keratin 8 (KRT8))
    别名
    Cytokeratin 8 (KRT8 产品)
    别名
    CARD2 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, K2C8 antibody, K8 antibody, KO antibody, AA960620 antibody, AL022697 antibody, AU019895 antibody, Card2 antibody, EndoA antibody, Krt-2.8 antibody, Krt2-8 antibody, CYKER antibody, KRT2-8 antibody, KERATIN8 antibody, ck8 antibody, cyk8 antibody, k2c8 antibody, card2 antibody, krt2-5 antibody, MGC69490 antibody, KRT8 antibody, DreK8 antibody, cb186 antibody, krt2-8 antibody, sb:cb186 antibody, wu:fa20h05 antibody, wu:fa95h10 antibody, wu:fb96c06 antibody, zf-K8 antibody, zfk8 antibody, DKFZp468F2127 antibody, keratin 8 antibody, keratin 8 S homeolog antibody, KRT8 antibody, Krt8 antibody, krt8.S antibody, krt8 antibody
    背景
    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual cytokeratin polypeptides are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
    基因ID
    3856
    NCBI登录号
    NP_002264
    UniProt
    P05787
You are here:
客服