AIF1 抗体 (Allograft Inflammatory Factor 1) (Biotin)

Details for Product anti-AIF1 Antibody No. ABIN112010, 供应商: Log in to see
抗原
  • fa04b11
  • wu:fa04b11
  • AIF1
  • aif1
  • AIF-1
  • IBA1
  • IRT-1
  • IRT1
  • Bart1
  • iba1
  • mrf-1
  • AI607846
  • D17H6S50E
  • G1
  • Iba1
  • AIF
  • AIF1L
  • allograft inflammatory factor 1
  • Allograft inflammatory factor 1
  • allograft inflammatory factor 1-like
  • aif1
  • AIF1
  • Aif1
  • LOC100350092
  • C9ORF58
适用
人, 大鼠
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107
97
8
7
2
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1
1
宿主
小鼠
142
56
36
2
1
克隆类型 (克隆位点)
单克隆 ()
标记
This AIF1 antibody is conjugated to Biotin
22
22
11
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
184
123
106
67
28
27
19
13
11
10
7
4
2
2
2
2
1
选项
Supplier
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Supplier Product No.
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免疫原 Purified Human recombinant AIF-1 Epitope is not further characterized.
克隆位点 1022-5
亚型 IgG2b
特异性 Recognizes AIF-1. This antibody BM4114B reacts with activated Macrophages / Microglial cells.
纯化方法 Affinity Chromatography.
别名 AIF1 (AIF1 Antibody 摘要)
背景 Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
基因ID 199
NCBI登录号 NP_001614
UniProt P55008
研究领域 Inflammation
途径 Smooth Muscle Cell Migration
应用备注 Immunohistochemistry on Paraffin Sections: 5 μg/mL (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
溶解方式 Restore by adding 0.5 mL distilled water.
浓度 0.2 mg/mL
缓冲液 PBS containing 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 This product is photosensitive and should be protected from light
储存条件 4 °C
储存方法 Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE!
背景 Schluesener, Seid, Meyermann: "Effects of autoantigen and dexamethasone treatment on expression of endothelial-monocyte activating polypeptide II and allograft-inflammatory factor-1 by activated macrophages and microglial cells in lesions of experimental autoimmune encephalomyelitis, n" in: Acta neuropathologica, Vol. 97, Issue 2, pp. 119-26, 1999 (PubMed).

Schluesener, Seid, Kretzschmar, Meyermann: "Allograft-inflammatory factor-1 in rat experimental autoimmune encephalomyelitis, neuritis, and uveitis: expression by activated macrophages and microglial cells." in: Glia, Vol. 24, Issue 2, pp. 244-51, 1998 (PubMed).

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