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Human MMP2 ELISA Kit for Sandwich ELISA - ABIN414819
Li, Liang, Tao, Zhou, Li, Chen, Chen: Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells. in Experimental biology and medicine (Maywood, N.J.) 2012
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Mouse (Murine) MMP2 ELISA Kit for Sandwich ELISA - ABIN411329
Morgunova, Tuuttila, Bergmann, Isupov, Lindqvist, Schneider, Tryggvason: Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. in Science (New York, N.Y.) 1999
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Human MMP2 ELISA Kit for Sandwich ELISA - ABIN411328
Kim, Choi, Lee, Choi, Lee, Hong, Yang, Yoo: Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis. in Rheumatology international 2011
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Rat (Rattus) MMP2 ELISA Kit for Sandwich ELISA - ABIN411386
Huhtala, Eddy, Fan, Byers, Shows, Tryggvason: Completion of the primary structure of the human type IV collagenase preproenzyme and assignment of the gene (CLG4) to the q21 region of chromosome 16. in Genomics 1990
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Human MMP2 ELISA Kit for Sandwich ELISA - ABIN625056
Yücel, Değim, Yilmaz: Nanoparticle and liposome formulations of doxycycline: transport properties through Caco-2 cell line and effects on matrix metalloproteinase secretion. in Biomedicine & pharmacotherapy 2013
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Wieslander, Marinis, Drewes, Keller, Acevedo, Word: Regulation of elastolytic proteases in the mouse vagina during pregnancy, parturition, and puerperium. in Biology of reproduction 2008
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Rat (Rattus) MMP2 ELISA Kit for Sandwich ELISA - ABIN416347
Michalski, Pelz, Weise, Kacza, Boltze, Grosche, Kamprad, Schneider, Hobohm, Härtig: Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. in Experimental & translational stroke medicine 2011
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Rat (Rattus) MMP2 ELISA Kit for Sandwich ELISA - ABIN365561
Kim, Ryu, Lee, Kim: Bevacizumab eye drops delay corneal epithelial wound healing and increase the stromal response to epithelial injury in rats. in Clinical & experimental ophthalmology 2013
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Mouse (Murine) MMP2 ELISA Kit for Sandwich ELISA - ABIN625167
Sun, Yu, Yu, Honglin, Ni, Zhang, Guo, He, Xue, Ni, Li, Feng, Chen, Shao, Chai, Li: Inhibition of the Activation and Recruitment of Microglia-Like Cells Protects Against Neomycin-Induced Ototoxicity. in Molecular neurobiology 2014
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Mouse (Murine) MMP2 ELISA Kit for Sandwich ELISA - ABIN415490
Shukla, Kumar Shakya, Dhole, Misra: Upregulated expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in BALB/c mouse brain challenged with Japanese encephalitis virus. in Neuroimmunomodulation 2012
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study demonstrated that matrix metalloproteinase 1 (显示 MMP1 ELISA试剂盒) and 2 might be fundamental for events related to equine tissue remodeling, which occurs during follicular development
Data indicate that matrix metalloproteinases mmp1 (显示 MMP1 ELISA试剂盒) and mmp2 mutants have distinct heart phenotypes.
We also show that follicular OA-Oamb signaling induces Mmp2 enzymatic activation but not Mmp2 protein expression, likely via intracellular Ca2 (显示 CA2 ELISA试剂盒)+ as the second messenger.
Finally, matrix metalloproteinase 2 (Mmp2), a type of protease thought to facilitate mammalian ovulation, is expressed in mature follicle and corpus luteum cells.
As a Wnt (显示 WNT4 ELISA试剂盒) signaling antagonist, MMP2 cleaves the glypican (显示 GPC1 ELISA试剂盒), reducing the ability of Dlp (显示 DMD ELISA试剂盒) to interact with the Wnt (显示 WNT4 ELISA试剂盒) ligand and promote its distribution.
Matrix metalloproteinase 2 is required for fat-body remodeling in Drosophila
Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila.
Dendrite reshaping of adult Drosophila sensory neurons requires matrix metalloproteinase MMP2-mediated modification of the basement membranes
Mmp2 expression in the developing air sac (显示 ADCY10 ELISA试剂盒) is controlled by the Drosophila FGF homolog Branchless and then participates in a negative feedback and lateral inhibition mechanism that defines the precise pattern of FGF signaling.
findings demonstrate a critical role for Mmp2 in tubulogenesis post-induction, and implicate Mmp2 in regulating dynamic and essential changes to the extracellular matrix
Dexamethasone and hydrocortisone alter expression and activity of MMP-2 and MMP-9 (显示 MMP9 ELISA试剂盒) in the embryonic zebrafish.
MMP-2 and -9 expression were suppressed significantly by treatment with SB-3CT. The data demonstrated, for the first time, that SB-3CT strongly reduced corneal lymphangiogenesis and macrophage infiltration during inflammation.
animals were submitted to the evaluation of Blood-Brain Barrier permeability and MMP-2 and MMP-9 (显示 MMP9 ELISA试剂盒) in striatum, hippocampus and cerebral cortex
High MMP2 expression is associated with abdominal aortic aneurysm.
Low MMP2 expression is associated with liver fibrosis.
Cleavage of beta-DG still occurred when both MMP-2 and MMP-9 (显示 MMP9 ELISA试剂盒) were knocked out in gamma - sarcoglycan (显示 SGCG ELISA试剂盒)-deficient mice. The study found that up-regulation of MMP-14 (显示 MMP14 ELISA试剂盒) is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy.
NH2-terminal truncated MMP-2 "primes" the kidney to enhanced susceptibility to I-R injury via induction of mitochondrial dysfunction.
Study demonstrated evidence of beta-dystroglycan cleavage by matrix metalloproteinase-2/-9 in permanent middle cerebral artery occlusion mouse brains; this cleavage was implicated in aquaporin-4 (显示 AQP4 ELISA试剂盒) redistribution and brain edema in cerebral ischemia.
These results indicate that increased MMP2 and MMP9 (显示 MMP9 ELISA试剂盒) activity in the brains of mouse adenovirus type 1-infected susceptible mice may be due to MMP activity produced by endothelial cells, astrocytes, and microglia, which in turn may contribute to blood-brain barrier disruption and encephalitis in susceptible mice.
Studies define a novel HMGA1 (显示 HMGA1 ELISA试剂盒)-MMP-2 pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.
activation of astrocyte MMP2/JNK1 (显示 MAPK8 ELISA试剂盒)/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model
The A/A genotype (OR=0.120) and A allele (OR=0.442) reduce the risk of recurrent depressive disorder occurrence in the examined polymorphisms for MMP-2, MMP-7 (显示 MMP7 ELISA试剂盒) and MMP-9 (显示 MMP9 ELISA试剂盒).
Data suggest that MMP2 expression in lung neoplasms can be regulated by dietary factors; here, metabolites of quercetin (an antioxidant, anticarcinogenic dietary supplement) quercetin-3-glucuronide and quercetin 3'-sulfate down-regulates expression of MMP2 in A549 cells; the mechanism for this enzyme repression appears to involve up-regulation of PPARgamma (显示 PPARG ELISA试剂盒).
MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA (显示 VEGFA ELISA试剂盒), VEGFR1 (显示 FLT1 ELISA试剂盒), VEGFR2 (显示 KDR ELISA试剂盒), HGF (显示 HGF ELISA试剂盒) and MMP2
Expression of MMP2 is suppressed by Rubus idaeus extract by down-regulating ERK1/2 (显示 MAPK1/3 ELISA试剂盒) signaling pathway.
The rates of CD44st and MMP2 expression were higher in squamous cell carcinomas than in adenocarcinomas, were closely associated with lymph node metastasis and TNM (显示 ODZ1 ELISA试剂盒) stage, and affected patients' prognoses.
characteristics involving MMP-2 and MMP-9 (显示 MMP9 ELISA试剂盒) in Chagas' disease to clarify their participation on the inflammation/regulation and fibrosis, and the synergistic or antagonistic role between them [Review]
This study showed a significantly greater prevalence of the C/C and C/T genotypes in the patients with age-related macular degeneration (AMD (显示 AMD1 ELISA试剂盒)) younger than 65 years and those aged >/=65 years, respectively.
The results indicated that MMP-2 -1306C/T and MMP-9 (显示 MMP9 ELISA试剂盒) -1562C/T polymorphisms might be associated with an increased risk of T-Cell acute lymphoblastic leukemia in a Chinese population.
Taken together, our data suggest that eupatilin inhibits TNFalpha (显示 TNF ELISA试剂盒)-induced MMP-2/-9 expression by suppressing NF-kappaB (显示 NFKB1 ELISA试剂盒) and MAPKAP-1 (显示 MAPKAP1 ELISA试剂盒) pathways via PPARalpha (显示 PPARA ELISA试剂盒). Our findings suggest the usefulness of eupatilin for preventing skin aging.
Our current findings revealed a significant correlation between the distribution of MMP-2 (-1306C/T) variants and chronic obstructive pulmonary disease severity in a Tunisian population.
this study shows that differential FFAR1 (显示 FFAR1 ELISA试剂盒) signaling is associated with gene expression or gelatinase granule release in bovine neutrophils
NADPH oxidase (显示 NOX1 ELISA试剂盒) plays an important role in proMMP-2 expression and activation and MMP-2 mediated SMC (显示 DYM ELISA试剂盒) proliferation occurs through the involvement of Spm (显示 NPC1 ELISA试剂盒)-Cer (显示 CBLN1 ELISA试剂盒)-S1P (显示 MBTPS1 ELISA试剂盒) signaling axis under ANG II (显示 AGT ELISA试剂盒) stimulation of PASMCs
The expression patterns of MMP1 (显示 MMP1 ELISA试剂盒), MMP2, and MMP8 (显示 MMP8 ELISA试剂盒) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1 (显示 MMP1 ELISA试剂盒), MMP2, and MMP8 (显示 MMP8 ELISA试剂盒) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1 (显示 MMP1 ELISA试剂盒), MMP2, and MMP8 (显示 MMP8 ELISA试剂盒) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.
The results showed that a decrease in MMP-1 (显示 MMP1 ELISA试剂盒) and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.
Activation of cytosolic MMP-9 (显示 MMP9 ELISA试剂盒) and MMP-2 was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.
Data indicate the involvement of PKC-alpha (显示 PKCa ELISA试剂盒) in proMMP-2 activation and inhibition of TIMP-2 (显示 TIMP2 ELISA试剂盒) expression by NF-kappaB (显示 NFKB1 ELISA试剂盒)-MT1-MMP (显示 MMP14 ELISA试剂盒)-dependent and -independent pathway.
Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14 (显示 MMP14 ELISA试剂盒)) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells.
Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase (显示 CA-P60A ELISA试剂盒) activity, but the pretreatment with TIMP-2 (显示 TIMP2 ELISA试剂盒) inhibits the increase in the enzyme activity
A differential pattern of matrix metalloproteinase-2 and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.
MMP-14 (显示 MMP14 ELISA试剂盒), MMP-2 and TIMP-2 (显示 TIMP2 ELISA试剂盒) are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.
we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (显示 MMP9 ELISA试剂盒), TIMP1 (显示 TIMP1 ELISA试剂盒), and NGAL (显示 LCN2 ELISA试剂盒) (also MMP2 in 220 kDa complex) without proteolytic activity.
Data demonstrate for the first time that MMP2 and MMP9 (显示 MMP9 ELISA试剂盒) are expressed in swine ovarian follicle both in theca and granulosa layers.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (显示 MMP9 ELISA试剂盒) and MMP-2, caspase-3 (显示 CASP3 ELISA试剂盒) and BDNF (显示 BDNF ELISA试剂盒)
MMP-2 may play an important role in regulating MLC1 turnover in the heart under normal physiological conditions
Oxygen for newborn resuscitation increases MMP-2/-9 activity resulting in tissue damage and influencing remodeling processes.
PI3K-dependent regulation of MT1-MMP (显示 MMP14 ELISA试剂盒) protein synthesis and subsequent activation of latent MMP-2 as critical events in neointimal hyperplasia after vascular injury.
MMP-2 processes dental sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis
contribution of MMPs to the inflammatory breakdown of the blood-CSF (显示 CSF2 ELISA试剂盒) barrier in vitro
The levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 (显示 MMP9 ELISA试剂盒) in the corpus luteum of swine during luteolysis are reported.
Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (显示 VEGFA ELISA试剂盒), pro-MMP-9 (显示 MMP9 ELISA试剂盒), MMP-2, VEGFR-1 (显示 FLT1 ELISA试剂盒), VEGFR-2 (显示 KDR ELISA试剂盒), and TIMP-1 (显示 TIMP1 ELISA试剂盒), which may contribute to the development of venous stenosis.
Inflammatory factors such as TNF-alpha (显示 TNF ELISA试剂盒) can stimulate MMP-2/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases
Results provide evidence that MMP-2 bears the potentiality to cleave alpha-DG enriched from rabbit skeletal muscle indicating that this degradation indeed might also occur in vivo.
In conclusion, MMP-2 could be responsible for the proteolysis of dystrophin (显示 DMD ELISA试剂盒).
Castor (显示 CASZ1 ELISA试剂盒) oil polymer induces bone formation with high matrix metalloproteinase-2 expression.
MMP2 spinal cord expression is increased in cervical spondylotic myelopathy.
Ulinastatin (显示 AMBP ELISA试剂盒) effectively inhibited the increased expression of MMP-2, MMP-3 (显示 MMP3 ELISA试剂盒), and iNOS (显示 NOS2 ELISA试剂盒) in degenerated NP cells induced by IL-1beta (显示 IL1B ELISA试剂盒) in vitro.
Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2, MMP-9 (显示 MMP9 ELISA试剂盒) and TIMP-1 (显示 TIMP1 ELISA试剂盒) in rabbits with acute paraquat poisoning.
The RNA interference targeting COX-2 (显示 COX2 ELISA试剂盒) can effectively inhibit the expression of COX-2 (显示 COX2 ELISA试剂盒) and MMP-2 in IL-1alpha stimulated rabbit corneal stromal cells in vitro.
Our results strongly suggest that ischaemic postconditioning may exert part of its cardioprotective effects through the inhibition of MMP-2 activity.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
, matrix metalloprotease 2
, matrix metalloproteinase
, matrix metalloproteinase 2
, 72 kDa type IV collagenase
, Gelatinase A
, matrix metalloproteinase-2
, 72 kDa gelatinase
, gelatinase A
, 72kD gelatinase
, 72kD type IV collagenase
, 72kDa gelatinase
, 72kDa type IV collagenase
, collagenase type IV-A
, matrix metalloproteinase-II
, neutrophil gelatinase
, matrix metalloproteinase 2 (72 KDa type IV collagenase)
, matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)